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ClinicalTrials.gov public records Last synced Oct 8, 2026, 4:46 PM EDT

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Showing 169–192 of 350 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Atrial Fibrillation Ablation Clear all
Completed Phase 2 Interventional Results available

Clinical Study of the CardioFocus Endoscopic Ablation System - Adaptive Contact (EAS-AC) for the Treatment of Symptomatic Atrial Fibrillation

NCT00971204
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
CardioFocus HeartLight Endoscopic Ablation System
Device
Lead sponsor
CardioFocus
Industry
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
10
States / cities
Birmingham, Alabama • Santa Monica, California • Royal Oak, Michigan + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2016 · Synced Oct 8, 2026, 4:46 PM EDT
Completed No phase listed Observational

Novel Cardiac Signal Processing System

NCT04112433
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
PURE EP 2
Device
Lead sponsor
BioSig Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Jacksonville, Florida • Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2022 · Synced Oct 8, 2026, 4:46 PM EDT
Terminated Phase 4 Interventional Results available

Effect of Dronedarone on Atrial Fibrosis Progression and Atrial Fibrillation Recurrence

NCT04704050
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation Recurrent
Interventions
dronedarone 400 mg Oral Tablet, Placebo
Drug
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Colorado Springs, Colorado • Atlanta, Georgia • New Orleans, Louisiana + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional

Reduction of Radiation Dose and Contrast Use During Cryoballoon Pulmonary Vein Isolation

NCT03786822
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Cryoballoon Pulmonary Vein Isolation - PVI
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 26, 2018 · Synced Oct 8, 2026, 4:46 PM EDT
Recruiting No phase listed Observational

Machine Learning in Atrial Fibrillation

NCT05371405
View directory record Official record
Conditions
Atrial Fibrillation, Arrhythmias, Cardiac
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 8, 2026, 4:46 PM EDT
Terminated Not applicable Interventional

Safety and Efficacy Study of the Combined Ablation Procedure to Treat Paroxysmal Atrial Fibrillation

NCT01103674
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Numeris®-AF Guided Coagulation System with VisiTrax®
Device
Lead sponsor
nContact Surgical Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Memphis, Tennessee • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 3, 2014 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Results available

ABLATE Post Approval Study - Synergy Ablation Lesions for Non-Paroxysmal Atrial Fibrillation

NCT01694563
View directory record Official record
Conditions
Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation
Interventions
Synergy Ablation System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
49
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 41 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Results available

Continued Access Protocol

NCT00889681
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Arctic Front Cardiac Cryoablation System
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years to 75 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
10
States / cities
Phoenix, Arizona • Los Angeles, California • Stanford, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Phase 3 Interventional

Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation

NCT01006876
View directory record Official record
Conditions
Thromboembolism
Interventions
Coumadin
Drug
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
1,584 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2015 · Synced Oct 8, 2026, 4:46 PM EDT
Completed No phase listed Observational

Ten-year Outcomes After AF Ablation

NCT01867099
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Valley Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
445 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional

Radiofrequency Ablation of Atrial Fibrillation Under Apnea

NCT04170894
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Periods of Apnea, Control Arm - No Periods of Apnea
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 80 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
6
States / cities
Bay Shore, New York • Manhasset, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 8, 2026, 4:46 PM EDT
Recruiting No phase listed Observational

Repeatable Evaluation of Functional Intra-procedural Signals for Effect in Pulsed Field Ablation REFINE-PFA

NCT07275151
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary vein isolation ablation
Device
Lead sponsor
CathVision ApS
Industry
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Ypsilanti, Michigan • Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Phase 4 Interventional Results available

Oral Steroids Before Pulmonary Vein Isolation to Improve Outcomes

NCT01206452
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Prednisone, Placebo, Ablation Procedure
Drug · Other · Procedure
Lead sponsor
Dhanunjaya Lakkireddy, MD, FACC
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 8, 2026, 4:46 PM EDT
Recruiting Not applicable Interventional

Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

NCT07298473
View directory record Official record
Conditions
Atrial Fibrillation (AF), Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation (PAF)
Interventions
Sphere-9 Catheter Ablation
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
22
States / cities
Birmingham, Alabama • La Jolla, California • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional

Efficacy of Different Ablation Strategies for Controlling Atrial Fibrillation

NCT00379301
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Radiofrequency ablation
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Phase 2 Interventional Results available

Vitamin C in Atrial Fibrillation Ablation

NCT03148236
View directory record Official record
Conditions
Atrial Fibrillation Ablation
Interventions
Vitamin C, Placebo
Drug · Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 8, 2026, 4:46 PM EDT
Completed No phase listed Observational

Prospective Study to Validate Ablation Parameters with MRI Based Scar for Left Atrial Ablation

NCT04363307
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
AF Ablation, MRI
Device
Lead sponsor
Ravi Ranjan
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 1, 2024 · Synced Oct 8, 2026, 4:46 PM EDT
Active, not recruiting Not applicable Interventional

STrategies for Catheter Ablation of peRsistent Atrial Fibrlllation

NCT04428944
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Wide Circumferential Pulmonary Vein Antrum Isolation (PVAI), Pulmonary Vein Antrum Isolation Plus Driver Ablation (PVAI+drivers), Pulmonary Vein Antrum Isolation Plus Box Isolation of Posterior Wall (PVAI+box)
Procedure
Lead sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Other
Eligibility
18 Years and older
Enrollment
617 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional

A Study of Strategies for Electrical Isolation of Pulmonic Veins for Curative Treatment of Atrial Fibrillation

NCT00434694
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary Vein Isolation (Radiofrequency Catheter Ablation)
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 25, 2015 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Results available

A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation

NCT05443594
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
669 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
40
States / cities
Birmingham, Alabama • Phoenix, Arizona • Jonesboro, Arkansas + 32 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 8, 2026, 4:46 PM EDT
Withdrawn No phase listed Observational

Dabigatran Versus Warfarin Anticoagulation Before and After Catheter Ablation for the Treatment of Atrial Fibrillation

NCT01607359
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Results available

Treatment of Persistent Atrial Fibrillation With Sphere-9 Catheter and Affera Mapping and Ablation System

NCT05120193
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Mapping and Ablation
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years to 80 Years
Enrollment
477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
19
States / cities
Birmingham, Alabama • Phoenix, Arizona • Jonesboro, Arkansas + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Phase 3 Interventional

Concomitant Treatment of Permanent Atrial Fibrillation

NCT00566787
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Surgical bipolar radiofrequency ablation using the AtriCure Bipolar System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
10
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • Grand Rapids, Michigan + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2012 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Phase 3 Interventional

Renal Artery Denervation In Addition to Catheter Ablation To Eliminate Atrial Fibrillation

NCT01873352
View directory record Official record
Conditions
Atrial Fibrillation, Hypertension
Interventions
catheter ablation, renal sympathetic denervation
Procedure
Lead sponsor
Meshalkin Research Institute of Pathology of Circulation
Network
Eligibility
18 Years to 75 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Short Hills, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 8, 2026, 4:46 PM EDT