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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Auditory stimulation during sleep Clear all
Recruiting Not applicable Interventional

Sleep Architecture & Cognition in Focal Epilepsy

NCT05794295
View directory record Official record
Conditions
Focal Epilepsy
Interventions
Acoustic Stimulation (AS), SHAM Stimulation
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 6, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Auditory Stimulation of Slow Wave Sleep and Memory in Mild Cognitive Impairment and Older Adults

NCT02608840
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Auditory stimulation during sleep, Sham Intervention
Other
Lead sponsor
Northwestern University
Other
Eligibility
60 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Sep 6, 2026, 5:58 AM EDT
Enrolling by invitation Not applicable Interventional

Auditory Stimulation Effects on Sleep and Memory in Patients With Epilepsy

NCT04788628
View directory record Official record
Conditions
Epilepsy
Interventions
Baseline, Motor procedural memory task, Motor procedural memory task plus auditory stimulation
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Sep 6, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Behavioral and Neural Characteristics of Adaptive Speech Motor Control

NCT06164717
View directory record Official record
Conditions
Speech
Interventions
Auditory feedback perturbation during speech, Visual feedback perturbation during reaching, DBS stimulation ON/OFF
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
4 Years and older
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 10, 2023 · Synced Sep 6, 2026, 5:58 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Sleep Spindles and Memory in Rolandic Epilepsy

NCT04569708
View directory record Official record
Conditions
Rolandic Epilepsy, Rolandic Epilepsy, Benign, Centrotemporal Epilepsy, Centrotemporal; EEG Spikes, Epilepsy of Childhood, Epilepsy; Seizure, Epilepsy
Interventions
Closed loop auditory stimulation
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
4 Years to 18 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 6, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults

NCT03911154
View directory record Official record
Conditions
Sleep
Interventions
Philips SmartSleep Technology--Continuous Fixed Interval modality, Philips SmartSleep Technology--Block modality, Philips SmartSleep Technology--In-Phase Adjustable modality
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 6, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Slow-wave Enhancement in Adults Aged 30-49

NCT04611828
View directory record Official record
Conditions
Sleep
Interventions
Philips SmartSleep
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
30 Years to 49 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Sep 6, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Restoring Spindle and Thalamocortical Efficiency in Early-Course Schizophrenia Patients Using Auditory Stimulation

NCT05956951
View directory record Official record
Conditions
Schizophrenia
Interventions
Closed-loop auditory stimulation, Sham auditory stimulation
Device
Lead sponsor
Fabio Ferrarelli
Other
Eligibility
18 Years to 40 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 6, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Pilot Study Comparing the Effectiveness of Two Different Methods of Acoustic Stimulation

NCT03600194
View directory record Official record
Conditions
Sleep Deprivation, Insufficient Sleep Syndrome, Healthy
Interventions
PowerSleep Stim, Northwestern Stim, PowerSleep Sham, NorthWestern Sham
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 50 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 13, 2021 · Synced Sep 6, 2026, 5:58 AM EDT
Terminated Not applicable Interventional

The Nightmare Augmented Protocol for Treatment of Nightmares in Veterans With PTSD

NCT05120674
View directory record Official record
Conditions
PTSD
Interventions
NAP, CPT, ERRT, Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
VA Eastern Kansas
Federal
Eligibility
18 Years to 99 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Leavenworth, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2021 · Synced Sep 6, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity

NCT04818112
View directory record Official record
Conditions
Parent-Child Relations, Maternal Behavior, Infant Behavior
Interventions
ATVV, Attention control
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Sep 6, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine

NCT04206059
View directory record Official record
Conditions
Sleep, Sedation Complication
Interventions
MRI, Quantitative Sensory Testing (QST), Home sleep study, Acoustic stimulation (65 decibels or db) up-slope of EEG with QST, Acoustic stimulation (65db) down-slope of EEG with QST, 0 db with QST, Dexmedetomidine, Breathe-Squeeze Task
Radiation · Diagnostic Test · Other + 1 more
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 6, 2026, 5:58 AM EDT
Completed Not applicable Interventional

Physiological Investigations of Movement Disorders

NCT01019343
View directory record Official record
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 6, 2026, 5:58 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Auditory Stimulation Effect on Brain Oscillations and Sleep Dependent Learning

NCT06688526
View directory record Official record
Conditions
Healthy Control
Interventions
Quiet Sounds, Sham Sounds
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 6, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional

Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles

NCT05452122
View directory record Official record
Conditions
Memory, Delayed
Interventions
Auditory and Electrical Stimulation
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 6, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia

NCT06386588
View directory record Official record
Conditions
Schizophrenia
Interventions
Closed loop auditory stimulation during sleep
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Sep 6, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Wrist-worn Device That Produces a Small Vibration on Sleep and Performance That Can Occur During and After Night Shift Work

NCT06665672
View directory record Official record
Conditions
Sleep Duration, Psychomotor Performance
Interventions
Wrist worn vibro-acoustic device
Device
Lead sponsor
Daniel Patterson, PhD, NRP
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 6, 2026, 5:58 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia

NCT04783571
View directory record Official record
Conditions
Schizophrenia
Interventions
Placebo, Auditory Stimulation
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 6, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional

Acoustic Stimulation, Sleep, and Cognitive-Emotional Processes in Young Adults With Anxiety and Depression Symptoms

NCT05802004
View directory record Official record
Conditions
Acoustic Stimulation
Interventions
Acoustic Stimulation (STIM), No Acoustic Stimulation (SHAM), Daily acoustic stimulation (STIM2), No daily acoustic stimulation (SHAM2)
Device
Lead sponsor
Michelle Stepan
Other
Eligibility
18 Years to 25 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 6, 2026, 5:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sounds Locked to ElectroEncephalogram Phase For the Acceleration of Sleep Onset Time

NCT05743114
View directory record Official record
Conditions
Sleep, Sleep Disturbance
Interventions
Elemind Neuromodulation (ENMod)
Device
Lead sponsor
Elemind Technologies, Inc.
Industry
Eligibility
21 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Sep 6, 2026, 5:58 AM EDT
Active, not recruiting Not applicable Interventional

Acoustic Stimulation for Seizure Suppression

NCT03198494
View directory record Official record
Conditions
Epilepsy
Interventions
Acoustic 1Hz Stimulation, Sham Background Noise
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 60 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 6, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurophysiologic Correlates of Hypersomnia

NCT01719315
View directory record Official record
Conditions
Major Depressive Disorder, Primary Hypersomnia, Bipolar Disorder, Narcolepsy, Primary Insomnia
Interventions
Acoustical slow wave induction
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 60 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 23, 2018 · Synced Sep 6, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

NCT05309473
View directory record Official record
Conditions
Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance, Alertness
Interventions
Philips SmartSleep Acoustic Stimulation Device, Sham (no Acoustic Stimulation)
Device
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 39 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 6, 2026, 5:58 AM EDT