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ClinicalTrials.gov public records Last synced Oct 16, 2026, 4:12 PM EDT

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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: BIG + Treatment As Usual Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Esthetics of Dental Composite and Adhesive System

NCT03716349
View directory record Official record
Conditions
Cavities of Teeth
Interventions
Pulp vitality testing, Photos, local and/or topical anesthetic, rubber dam, tooth surface cleaned, enamel margins, Adhesive Systems, cavity preparation, Shade selection using Easy Shade 5, Light Curing, Contoured and polished, Consent, Health Questionnaire, xray, Release of medical information signed, Oral Exam, Teeth Assessment, Clinical Assessment, Tokuyama Universal Bond, ScotchBond
Diagnostic Test · Other · Drug + 3 more
Lead sponsor
Erica Teixeira
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 16, 2026, 4:12 PM EDT
Recruiting Not applicable Interventional

Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.

NCT04730700
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Radiofrequency Ablation with MEE, Conventional Medical Management
Procedure · Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional Results available

Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project

NCT03799341
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Prize-Based Contingency Management, Treatment As Usual Outpatient Substance Use Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 16, 2026, 4:12 PM EDT
Active, not recruiting Not applicable Interventional

The T1D Parent Check-In: A Preventative Intervention

NCT06160934
View directory record Official record
Conditions
Type 1 Diabetes, Diabetes in Children
Interventions
T1D Parent Check-in
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 16, 2026, 4:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Clinic-wide Intervention (Primary Care-GI Connect) for Improving Rates of Colonoscopy After Abnormal Fecal Immunochemical Test Result in Patients at Federally Qualified Health Centers

NCT06568016
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Best Practice, Communication Intervention, Coordination, Educational Intervention, Electronic Health Record Review, Informational Intervention, Interview, Patient Navigation, Referral, Text Message-Based Navigation Intervention
Other · Behavioral
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
Not listed
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional Results available

Robotic Walking Device to Improve Mobility in Parkinson's Disease

NCT03751371
View directory record Official record
Conditions
Parkinson Disease
Interventions
Training with HWA device, Usual Care
Device · Other
Lead sponsor
Ohio State University
Other
Eligibility
50 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional

Implementing Digital Health in a Learning Health System

NCT03713333
View directory record Official record
Conditions
Cardiovascular Diseases, Hypertension, Heart Failure, Atrial Fibrillation, Metabolic Syndrome, Genetic Disease
Interventions
Digital Health Device Diagnostics
Diagnostic Test
Lead sponsor
Scripps Health
Other
Eligibility
18 Years and older
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 16, 2026, 4:12 PM EDT
Terminated Not applicable Interventional Results available

Trial Comparing PLA to HIGRT (PROVE-HCC)

NCT03402607
View directory record Official record
Conditions
Hepatocellular Carcinoma
Interventions
Percutaneous Local Ablation, Hypofractionated Image Guided Radiation Therapy
Procedure · Radiation
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 16, 2026, 4:12 PM EDT
Recruiting Not applicable Interventional

BIG Chicago: A Trial of Basic Income Guarantee for Young People Living With HIV

NCT07502365
View directory record Official record
Conditions
HIV, Financial Stress
Interventions
Treatment As Usual, BIG + Treatment As Usual
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 35 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 16, 2026, 4:12 PM EDT
Terminated Phase 2 Interventional Results available

Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer

NCT00281879
View directory record Official record
Conditions
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Unusual Cancers of Childhood
Interventions
anti-thymocyte globulin, filgrastim, busulfan, carmustine, cyclophosphamide, cyclosporine, cytarabine, etoposide, fludarabine phosphate, melphalan, methotrexate, methylprednisolone, mycophenolate mofetil, tacrolimus, peripheral blood stem cell transplantation, umbilical cord blood transplantation, radiation therapy
Biological · Drug · Procedure + 1 more
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
Up to 60 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 27, 2017 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Collaborative Efforts to Increase Flu Vaccination

NCT01403649
View directory record Official record
Conditions
Influenza, Collaboration
Interventions
Private/public collaboration to increase flu vaccination, Usual care
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
6 Months to 18 Years
Enrollment
117,175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
27
States / cities
Aurora, Colorado • Brighton, Colorado • Broomfield, Colorado + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Tool for Preventing Prenatal Drinking

NCT02337361
View directory record Official record
Conditions
Foetal Exposure During Pregnancy
Interventions
Electronic SBI
Behavioral
Lead sponsor
Public Health Institute, California
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
2
States / cities
Oakland, California • Santa Rosa, California
Source: ClinicalTrials.gov public record
Updated Jan 25, 2019 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional Results available

Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Techniques for the Treatment of Large Long Bone Defects

NCT02015390
View directory record Official record
Conditions
Segmental Long Bone Defects
Interventions
Autogenous RIA bone grafting, Allogeneic bone grafting
Procedure
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 99 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional

Adaptive Symptom Care Using Fish-Based Nutritional Directives Post Breast Cancer

NCT04293874
View directory record Official record
Conditions
Fatigue, Depression, Pain, Sleep Disturbance, Stress, Survivorship, Breast Cancer, Dietary Habits
Interventions
Personalized Meal Plan, Dietary Omega-3LC intervention
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
35 Years to 70 Years · Female only
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 16, 2026, 4:12 PM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional Results available

Nueva Vida Intervention for Latina Breast Cancer Survivors and Caregivers

NCT02222337
View directory record Official record
Conditions
Quality of Life, Breast Cancer
Interventions
Nueva Vida Intervention
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
Up to 85 Years
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
San Jose, California • Washington D.C., District of Columbia • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Oct 16, 2026, 4:12 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing the Care Transitions Intervention With Peer Support to Reduce Disparities

NCT04981977
View directory record Official record
Conditions
Hospital Readmissions
Interventions
Care Transitions Intervention, Care Transitions Intervention and Peer Support, Usual Care
Behavioral · Other
Lead sponsor
University of South Florida
Other
Eligibility
60 Years and older
Enrollment
483 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

ElderTree Smart System for Older Adults

NCT04798196
View directory record Official record
Conditions
Chronic Pain
Interventions
ElderTree on laptop (ET- LT), ElderTree on smart system (ET- SS), Treatment as usual (TAU)
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
60 Years and older
Enrollment
268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Phase 2 Interventional

Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS

NCT04046991
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
high-definition transcranial direct current stimulation, modified constraint-induced language therapy
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 80 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Phase 4 Interventional Results available

Improved Induction and Maintenance Immunosuppression in Kidney Transplantation

NCT00556933
View directory record Official record
Conditions
End-stage Renal Disease
Interventions
rabbit anti-thymocyte globulin - single dose, mycophenolate mofetil, rabbit anti-thymocyte globulin - 4 doses, sirolimus, tacrolimus
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 18, 2023 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Title: Comparative Effectiveness of Asthma Interventions Within an AHRQ PBRN

NCT01280500
View directory record Official record
Conditions
Asthma
Interventions
electronic medical record, Integrated Approach to Care, usual care, Shared Decision Making, school based care
Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
1,040 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
2
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Phase 2 Interventional

PCT for Speech, Language, and Cognitive Intervention in Stroke Patients

NCT04488029
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
PCT, Workbooks
Other
Lead sponsor
The Learning Corp
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Oct 16, 2026, 4:12 PM EDT
Completed Not applicable Interventional

Mental Health Resources for Frontline Healthcare Workers

NCT05113316
View directory record Official record
Conditions
Mental Health
Interventions
Messy Memories App
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 89 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Oct 16, 2026, 4:12 PM EDT
Not yet recruiting Not applicable Interventional

Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities

NCT06915428
View directory record Official record
Conditions
Preterm Birth Complication, Preterm Birth, Preterm Birth Recurrence, Preeclampsia, Preeclampsia (PE), Hypertensive Disorders of Pregnancy, Support Program, Stress, Resilience, Psychological, Empowerment, Patient, Emotional Stress, Pregnancy, Pregnancy Complications, Pregnancy Induced Hypertension, Neonates and Preterm Infants, Cervical Insufficiency, Social Determinants of Health (SDOH), Cervical Shortening, Disparities in Pregnancy Complications, Disparities, Prenatal Care, Care Coordination
Interventions
Care coordination, Electronic massage, support gift #1, Support gift #2, Support gift #3, Support gift #4, Additional PTBCARE+ support, Stress reduction toolkit - Visit 1 (V1), PTBCARE+ mobile application (app) and website, Sleep, meditation, and Wellness app, Emergency low blood sugar kit, Low dose aspirin (LDA), Visit #2 Stress Reduction Toolkit
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
1,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 16, 2026, 4:12 PM EDT