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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: BNI Clear all
Active, not recruiting Not applicable Interventional

Promoting Alcohol Treatment Engagement Post-hospitalization

NCT05338151
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Brief Negotiated Interview (BNI), BNI+facilitated provision of MAUD, Brief Negotiated Interview BNI+facilitated provision of MAUD+CBT4CBT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 2, 2026, 2:14 AM EDT
Not yet recruiting Not applicable Interventional

Substance Use in Assault-Injured Young Adults

NCT07070414
View directory record Official record
Conditions
Alcohol Misuse, Cannabis Misuse
Interventions
Brief Negotiation Interview intervention (BNI) (adapted)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 25 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 2, 2026, 2:14 AM EDT
Recruiting Phase 3 Interventional

Emergency Department-Initiated Medications for Alcohol Use Disorder

NCT05827159
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Naltrexone Pill, Naltrexone Injection, Brief Negotiation Interview, Gabapentin Pill
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Not applicable Interventional

Integrated Stepped Care for Unhealthy Alcohol Use in HIV

NCT01410123
View directory record Official record
Conditions
Liver Diseases, Alcoholic, Alcoholism, HIV, Hepatitis C
Interventions
Integrated Stepped Care (ISC), Treatment as Usual
Other
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
319 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2022 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Phase 2Phase 3 Interventional

Enhancing Emergency Practitioner (EP)-Performed Alcohol Interventions in the Emergency Department (ED)

NCT00261859
View directory record Official record
Conditions
Harmful Drinking
Interventions
BNI
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Brief Negotiation Interview Chatbot to Improve Buprenorphine Engagement Among Justice-Involved Individuals

NCT04982627
View directory record Official record
Conditions
Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe, Criminal Behavior
Interventions
BNI Chatbot, OUD Education & Treatment Resources
Behavioral
Lead sponsor
Center for Progressive Recovery, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Not applicable Interventional

Automated Bilingual Computerized Alcohol Screening and Intervention in Latinos (AB-CASI)

NCT02247388
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Computerized Alcohol Screening, Brief Negotiated Interview
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Bridgeport, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Phase 3 Interventional

Brief Intervention to Reduce STDs in ER Drug Users

NCT01379599
View directory record Official record
Conditions
Sexually Transmitted Infection
Interventions
brief motivation intervention
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 54 Years
Enrollment
1,030 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2016 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Combination SBIRT for Emergency Department Patients Who Drink and Smoke

NCT01595178
View directory record Official record
Conditions
Smoking, Drinking
Interventions
Combined BNI
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Intervention Study To Improve Human PapillomaVirus ( HPV) Immunization in Haitian and African American Girls

NCT01254669
View directory record Official record
Conditions
Cervical Cancer
Interventions
BNI-brief Negotiated Interview
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
11 Years to 15 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Not applicable Interventional

Emergency Physician Brief Interventions for Alcohol

NCT00443183
View directory record Official record
Conditions
Harmful Drinking, Hazardous Drinking
Interventions
Brief Negotiation Interview (BNI), Discharge Instructions
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Phase 3 Interventional Results available

Optimizing Tobacco Dependence Treatment in the Emergency Department

NCT02896400
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Brief Negotiated Interview (BNI), Nicotine replacement therapy (NRT), CT Smokers Quitline (QL), SmokefreeText (Text)
Behavioral · Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
1,056 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrating Primary & Secondary Interventions for Cervical Cancer Prevention in Primary Care Settings

NCT03033550
View directory record Official record
Conditions
HPV-Related Carcinoma
Interventions
brief negotiated mobile application
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
9 Years to 17 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2018 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Not applicable Interventional

Study of an Emergency Department-based Intervention to Reduce Alcohol Misuse in Older Adults

NCT02236494
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Brief Negotiated Interview, General Health Information
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years and older
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Sep 2, 2026, 2:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Primary Connections for Youth and Families

NCT05964010
View directory record Official record
Conditions
Substance Use
Interventions
Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI), Standard Referral to Treatment (RT), Family Screening, Family Psychoeducation, Family Brief Negotiated Interview (BNI), Family Facilitated Conversation (FC) & Referral to Treatment (RT)
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
12 Years to 17 Years
Enrollment
2,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrating a Health Information Technology System for Primary and Secondary Cervical Cancer Prevention

NCT03346915
View directory record Official record
Conditions
Human Papilloma Virus, Cervical Cancer, Human Papillomavirus Infection, Oropharyngeal Cancer, Vaginal Cancer, Vulvar Cancer, Anal Cancer, Penile Cancer
Interventions
WoW and BNI
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
9 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Sep 2, 2026, 2:14 AM EDT
Completed Not applicable Interventional Results available

Models of Screening, Brief Intervention With a Facilitated Referral to Treatment (SBIRT) for Opioid Patients in the Emergency Department

NCT00913770
View directory record Official record
Conditions
Opiate Addiction
Interventions
Brief Negotiation Interview (BNI), Buprenorphine Initiation
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Sep 2, 2026, 2:14 AM EDT