- Conditions
- Dry Eye Syndrome
- Interventions
- BRM421, Placebo
- Drug
- Lead sponsor
- BRIM Biotechnology Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 220 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 4
- States / cities
- Newport Beach, California • Indianapolis, Indiana • Andover, Massachusetts + 1 more
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- Conditions
- Dry Eye Syndrome
- Interventions
- BRM421, Placebo
- Drug
- Lead sponsor
- BRIM Biotechnology Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 157 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 2
- States / cities
- Lewiston, Maine • Andover, Massachusetts
- Conditions
- Dry Eye Disease
- Interventions
- BRM421 Ophthalmic Solution, Vehicle
- Drug
- Lead sponsor
- BRIM Biotechnology Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 740 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Warwick, Rhode Island
- Conditions
- Limbal Stem Cell Deficiency (LSCD)
- Interventions
- BRM421 Ophthalmic Solution, 0.06%
- Drug
- Lead sponsor
- BRIM Biotechnology Inc.
- Industry
- Eligibility
- 18 Years and older
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania