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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:05 AM EDT

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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Barbed suture Clear all
Completed Not applicable Interventional Results available

Barbed Suture Versus Non-Barbed Suture for Posterior Colporrhaphy

NCT04658784
View directory record Official record
Conditions
Rectocele
Interventions
2-0 dioxanone, glycolide and trimethylene carbonate, 2-0 polydioxanone
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Dermal Closure With an Absorbable Barbed Suture as Compared to a Conventional Absorbable Suture

NCT00959374
View directory record Official record
Conditions
Breast Ptosis, Obesity
Interventions
V-Loc 180/90 Wound Closure Device, 3-0 Monocryl Absorbable Sutures
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
6
States / cities
Chicago, Illinois • Worcester, Massachusetts • Albany, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2013 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Barbed Suture for Hysterotomy Closure During Cesarean Section

NCT04622267
View directory record Official record
Conditions
Hysterotomy
Interventions
Barbed suture, Standard antimicrobial suture
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Oct 22, 2026, 2:05 AM EDT
Not yet recruiting Not applicable Interventional

Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT

NCT06043414
View directory record Official record
Conditions
Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen, Emergency General Surgery
Interventions
triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 100 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Robotic Versus Laparoscopic Ventral Hernia Repair

NCT03490266
View directory record Official record
Conditions
Hernia, Ventral
Interventions
Robotic Repair, Laparoscopic Repair
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Oct 22, 2026, 2:05 AM EDT
Terminated Not applicable Interventional

Pelvic Floor Support After Laparoscopic Hysterectomy for Benign Conditions: A Randomized Controlled Trial Comparing Vaginal Cuff Closure Techniques

NCT03753516
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Laparoscopic - Vaginal Cuff Closure, Vaginal- Vaginal Cuff Closure
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 22, 2026, 2:05 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

a Study to Evaluate Adhesion Risk in Fertility Patients' Status Post Laparoscopic Myomectomy.

NCT01971060
View directory record Official record
Conditions
Uterine Fibroids, Infertility
Interventions
surgery utilizing V-Loc suture
Device
Lead sponsor
The Advanced Gynecologic Surgery Institute
Other
Eligibility
18 Years to 42 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Naperville, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Oct 22, 2026, 2:05 AM EDT
Not yet recruiting Not applicable Interventional

Knotless Versus Conventional Sutures for Wound Closure in Cerebral Palsy Multilevel Surgery

NCT07880197
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Knotless barbed suture, Conventional suture
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Active, not recruiting Not applicable Interventional

Barbed-suture Efficiency Study for Sacrocolpopexy

NCT05760794
View directory record Official record
Conditions
Prolapse; Female
Interventions
Non-barbed delayed absorbable suture, Barbed delayed absorbable suture
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Postoperative Bleeding After Hysterectomy Via Independent Closure of Vaginal Cuff Angles

NCT05174988
View directory record Official record
Conditions
Postoperative Bleeding, Patient Satisfaction, Complications, Operative Time
Interventions
Angle stitch
Procedure
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 22, 2026, 2:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Analysis of Standard Versus Barbed Sutures in Primary Total Knee Arthroplasty.

NCT01320371
View directory record Official record
Conditions
Arthropathy of Knee
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
363 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
4
States / cities
Durham, North Carolina • New Albany, Ohio • Temple, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2014 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

Knotless Suture in Revision Total Joint Arthroplasty

NCT04403919
View directory record Official record
Conditions
Arthroplasty
Interventions
Conventional Closure: Knee, Barbed suture closure: Knee, Conventional Closure: Hip, Barbed suture closure: Hip
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Show the Safety and Effectiveness of the Demetech Barbed Polydioxanone (PDO) Suture

NCT06404372
View directory record Official record
Conditions
Wrinkle
Interventions
Demetech Barbed PDO Suture
Device
Lead sponsor
Sutura Medical Technology LLC
Industry
Eligibility
22 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
4
States / cities
Los Angeles, California • Sherman Oaks, California • The Woodlands, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 22, 2026, 2:05 AM EDT
Recruiting Phase 4 Interventional

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

NCT07225101
View directory record Official record
Conditions
Wound Closure, Brain Tumor Adult, Spine, Neurovascular, Hemorrhagic Stroke, Intracerebral, Traumatic Brain Injury
Interventions
STRATAFIX PDS and Monocryl suture
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 22, 2026, 2:05 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Affixing Polypropylene Mesh Using Barbed Suture (Quill™ SRS) During Robotic Assisted Laparoscopic Sacrocolpopexy

NCT01608568
View directory record Official record
Conditions
Prolapse
Interventions
Device is the type of suture used: Quill suture vs. Interrupted suture
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2012 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

The Use of STRATAFIX Suture Device Compared to Standard-of-care for Deep Tissue Closure in Total Knee Arthroplasty

NCT03285529
View directory record Official record
Conditions
Wound; Knee
Interventions
STRATIFIX, VICRYL
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Affixing Polypropylene Mesh Using Barbed Suture (Quill™ Srs) During Laparoscopic Sacrocolpopexy Randomized Controlled Trial (Quill Lsc)

NCT01551992
View directory record Official record
Conditions
Prolapse
Interventions
Quill suture vs. Interrupted suture
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2014 · Synced Oct 22, 2026, 2:05 AM EDT
Not listed Not applicable Interventional

Vaginal Cuff Closure Time Using Unidirectional Barbed Suture in Robotic Hysterectomy

NCT01814579
View directory record Official record
Conditions
Disease (or Disorder); Gynecological
Interventions
Unidirectional Barbed Suture (V-Loc), polyglactin 910 (Vicryl)
Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 26, 2013 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study to Compare Suture Material in Closure of Uterine Incision in Cesarian Section

NCT02517710
View directory record Official record
Conditions
Hysterotomy Closure
Interventions
Stratafix synthetic barbed suture
Procedure
Lead sponsor
Evangelical Community Hospital, Lewisburg, PA
Other
Eligibility
16 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Lewisburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2018 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

Prospective Randomized Trial of Stratafix vs. Vicryl in Total Hip Arthroplasty.

NCT03285555
View directory record Official record
Conditions
Wound; Hip
Interventions
STRATIFIX, VICRYL
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 22, 2026, 2:05 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Zip-Stitch™ for Vaginal Cuff Closure in Laparoscopic Hysterectomy - Safety & Efficacy Study

NCT04081727
View directory record Official record
Conditions
Laparoscopic Hysterectomy
Interventions
Zip-stitch(TM)
Device
Lead sponsor
ZSX Medical LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 7, 2022 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Comparative Analysis of Sutures for Fascial Closure in Spinal Surgery

NCT03533595
View directory record Official record
Conditions
Fusion of Spine
Interventions
Barbed
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 22, 2026, 2:05 AM EDT
Completed Phase 4 Interventional Results available

Barbed Suture vs Smooth Suture for Vaginal Cuff Closure

NCT01262573
View directory record Official record
Conditions
Closure of Vaginal Cuff at Laparoscopic Hysterectomy
Interventions
Closure of vaginal cuff
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 16, 2017 · Synced Oct 22, 2026, 2:05 AM EDT
Terminated Not applicable Interventional

Investigating a Novel Modifiable Factor Affecting Renal Function After Partial Nephrectomy: Cortical Renorrhaphy

NCT02131376
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
Non-renorrhaphy, Renorrhaphy
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Oct 22, 2026, 2:05 AM EDT