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Showing 145–168 of 213 matching trials from the live ClinicalTrials.gov search.
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Mechanisms Underlying Metabolic Syndrome in Obesity

NCT00579813
Conditions
Metabolic Syndrome, Insulin Resistance, Prediabetes
Interventions
Pioglitazone
Drug
Lead sponsor
Philip Kern
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
2
States / cities
Little Rock, Arkansas • Lexington, Kentucky
Conditions
Trauma-related PTSD
Interventions
Trauma Focused CBT (TF-CBT), Trauma Systems therapy (TST)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
5 Years to 17 Years
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Wearable Neural Interfacing System for REM Sleep Restoration and Enhancement

NCT07190287
Conditions
Sleep Disturbance, Stress, Psychological, REM Sleep Measurement
Interventions
NEUSleeP system (FUS-EEG wearable device), BrainSonix Pulsar 1002
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Austin, Texas
Conditions
Aphasia
Interventions
Semantic Feature Analysis (SFA)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
San Francisco, California • Boston, Massachusetts • Austin, Texas
Conditions
Down Syndrome
Interventions
Enhanced Milieu teaching
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Months to 36 Months
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Intensive Care Unit Acquired Weakness (ICUAW)
Interventions
FES-Cycling, Standard Care
Device · Other
Lead sponsor
Associate Professor Sue Berney PhD, BPT
Other
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Baltimore, Maryland • Durham, North Carolina
Conditions
Opioid-use Disorder, Mental Health Conditions
Interventions
Collaborative Care for Opioid Use Disorders and Mental Health Conditions, Augmented Usual Care, Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
567 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Optimal TTM Tailoring for Population Cessation

NCT01544010
Conditions
Smoking Cessation
Interventions
Stage-Tailored Manual, Stage Tailored Feedback Report, Moderate TTM-Tailored Feedback Report, Full TTM-Tailored Feedback Report, Enhanced TTM+Addiction Tailored Feedback Report
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
3,006 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Kingston, Rhode Island
Enrolling by invitation Not applicable Interventional

Reducing Overuse of Antibiotics at Discharge Home

NCT06106204
Conditions
Pneumonia, Urinary Tract Infection, Antibiotic Stewardship, Care Transition
Interventions
ROAD Home Intervention
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Hepatitis C
Interventions
Integrated care model, Usual Care Model
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 75 Years
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
3
States / cities
Palo Alto, California • San Diego, California • The Bronx, New York
Enrolling by invitation Not applicable Interventional

Core Competency Model for Corrections

NCT06359574
Conditions
Knowledge, Attitudes, Practice
Interventions
Core Competency Model for Corrections (CCM-C) Self-Directed Violence Prevention Training
Other
Lead sponsor
University of North Carolina, Charlotte
Other
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Conditions
Diabetes Mellitus, Type 1
Interventions
EMR-based BPA model, Placebo (EMR-based without BPA model)
Other · Behavioral
Lead sponsor
T1D Exchange, United States
Other
Eligibility
2 Years to 95 Years
Enrollment
1,178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD), Metabolic Associated-dysfunction Steatohepatitis (MASH)
Interventions
Standard of care acceptance-based behavioral weight loss program, Occupational therapy dietary and lifestyle modifications
Behavioral
Lead sponsor
Grand Valley State University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Wyoming, Michigan
Conditions
Suicide Risk
Interventions
TIPS Program, TIPS Program + ED-SAFE
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
32,406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Worcester, Massachusetts
Completed Not applicable Interventional Results available

Implementation of Women's Health Patient Aligned Care Teams

NCT02039856
Conditions
Patient-centered Medical Home Implementation
Interventions
Multilevel stakeholder engagement, Quality improvement (QI) education/training, Technical support, Formative feedback, External practice facilitation, National policy guidance
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
3,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
13
States / cities
Sepulveda, California • West Haven, Connecticut • Chicago, Illinois + 10 more
Conditions
Adolescent Behavior, Mental Health Issue
Interventions
Navigation Arm, Control Arm
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
4 Years to 12 Years
Enrollment
358 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Oakland, California • Seattle, Washington
Conditions
Advanced Breast Carcinoma, Locally Advanced Breast Carcinoma, Metastatic Breast Carcinoma, Recurrent Breast Carcinoma, Stage III Breast Cancer AJCC v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7
Interventions
Biopsy, Biospecimen Collection, Laboratory Biomarker Analysis
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Conditions
Nicotine Dependence, Transcranial Magnetic Stimulation, Vaping, Smoking Cessation, Smoking (Tobacco) Addiction
Interventions
Varenicline, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham, Nicotine Cessation Counseling, D-cycloserine
Drug · Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Brain Tumor
Interventions
Magnetic Resonance Imaging, Diffusion Tensor Imaging, Magnetic Resonance Spectroscopic Imaging, Dynamic Contract-Enhanced magnetic resonance imaging, Diffusion-weighted magnetic resonance imaging
Procedure
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Otitis Media With Effusion (OME), Eustachian Tube Dysfunction, Otitis Media With Effusion
Interventions
EarFlo Device
Device
Lead sponsor
Philip Perez
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
4
States / cities
Pittsburgh, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers

Development of a Model of Shoulder Pain Following Spinal Cord Injury

NCT03137394
Conditions
Spinal Cord Injury
Interventions
Observation
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Gwynn Oak, Maryland • Philadelphia, Pennsylvania
Conditions
HIV, Heart Failure
Interventions
Exercise Intervention, Tailored Education sessions, Behavioral coaching, Mobile health support, General education
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Heart Failure
Interventions
Provider-Based Care Model Arm, mHealth Model Arm
Other · Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
55 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Little Rock, Arkansas
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Development of Adaptive Deep Brain Stimulation for OCD

NCT04281134
Conditions
Obsessive-Compulsive Disorder
Interventions
Summit RC+S System, One Month Blinded Discontinuation Period:
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas