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Conditions: Healthy Volunteers
Interventions: SKY0402; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: San Diego, California

Conditions: Kidney Transplantation
Interventions: Belatacept; Drug
Lead sponsor: East Carolina University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Greenville, North Carolina

Conditions: SCI - Spinal Cord Injury
Interventions: Dalfampridine, Placebo, STDP stimulation, Exercise training; Drug · Other · Behavioral
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 85 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Depression, Anxiety
Interventions: Initial Coaching Call, Email Support, Text Messages; Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: HIV
Interventions: Condom choices, Condom-compatible lubricant choices, Couples HIV counseling and testing (CVCT), Pre-exposure prophylaxis with FTC/TDF, Staff and provider MSM and LGBT sensitization training, HIV Testing and Risk-reduction counseling, Linkage to care; Behavioral · Drug · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Atlanta, Georgia • Baltimore, Maryland

Conditions: Type 2 Diabetes, Obesity
Interventions: Portion-controlled diet, Usual Diet; Other · Dietary Supplement
Lead sponsor: Nutrisystem, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Maternal Depression
Interventions: Project Solve Education; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: Female only
Enrollment: 188 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 4
States / cities: Boston, Massachusetts • Natick, Massachusetts • Quincy, Massachusetts + 1 more

Conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Nonmalignant Neoplasm
Interventions: trivalent influenza vaccine, Immunoenzyme technique, Laboratory biomarker analysis; Biological · Other
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 18 Years to 120 Years
Enrollment: 459 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2013
U.S. locations: 2
States / cities: Duarte, California • Pasadena, California

Conditions: Relapsed Ewing Sarcoma, Refractory Ewing Sarcoma, Relapsed Osteosarcoma, Refractory Osteosarcoma
Interventions: Cabozantinib, Topotecan, Cyclophosphamide, Myeloid growth factor; Drug
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 6 Years to 30 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Chronic Pain, Hemiplegic Shoulder Pain
Interventions: StimRouter Neuromodulation System; Device
Lead sponsor: Bioness Inc; Industry
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 2
States / cities: Miami, Florida • Salt Lake City, Utah

Conditions: GBAT+Individual, GBAT+Engagement Booster, GBAT+Both
Interventions: GBAT+I, GBAT+E - Phase I, Watchful Waiting and Groups - Phase 2, GBAT+IE; Other
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 40 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Piscataway, New Jersey

Conditions: Depression, Postpartum
Interventions: NeuroStar Transcranial Magnetic Stimulation (TMS); Device
Lead sponsor: Neuronetics; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 8
States / cities: Hartford, Connecticut • Gainesville, Florida • Pensacola, Florida + 5 more

Conditions: Chronic Pelvic Pain Syndrome (CPPS), Chronic Pelvic Pain Syndrome, Chronic Pelvic Pain
Interventions: Pelvic floor yoga, Physical conditioning; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Female only
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Pregnancy Related
Interventions: Standard Care with Well-Mama Intervention; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 15 Years to 49 Years · Female only
Enrollment: 576 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Baton Rouge, Louisiana • Newark, New Jersey

Conditions: Type 1 Diabetes
Interventions: Diabetes behavior change skills training, Physical activity promotion program; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 13 Years to 17 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Bladder Cancer
Interventions: P3BC; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: New York, New York • Seattle, Washington

Conditions: Lung Cancer, Melanoma, Head and Neck Carcinoma, Gastroesophageal Cancer, Breast Cancer, Pancreatic Adenocarcinoma, Colorectal Cancer, Biliary Tract Cancer
Interventions: Selumetinib, MEDI4736, Tremelimumab; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 6
States / cities: Chicago, Illinois • Boston, Massachusetts • Las Vegas, Nevada + 3 more

Conditions: Macular Edema, Central Retinal Vein Occlusion, Hemiretinal Vein Occlusion
Interventions: Faricimab, Aflibercept, Sham Procedure; Drug · Procedure
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 18 Years and older
Enrollment: 729 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 57
States / cities: Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 52 more

Conditions: Quality of Life, Breast Cancer
Interventions: Nueva Vida Intervention; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: Up to 85 Years
Enrollment: 272 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 4
States / cities: San Jose, California • Washington D.C., District of Columbia • New York, New York

Conditions: Ulcerative Colitis
Interventions: RO7837195, RO7837195 Matched Placebo; Drug
Lead sponsor: Genentech, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 8
States / cities: Lancaster, California • San Diego, California • Colorado Springs, Colorado + 5 more

Conditions: Aphasia
Interventions: Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 90 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Crohn's Disease, Active, Crohn's Disease (CD), Diet Interventions
Interventions: Catered Anti-Inflammatory Diet, Diet Guidance for Usual Diet; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 16 Years to 75 Years
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Miami, Florida

Conditions: End Stage Renal Disease
Interventions: Group 1: GranuFlo, Group 2: NaturaLyte; Device
Lead sponsor: Fresenius Medical Care North America; Industry
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: TBI (Traumatic Brain Injury), PTSD
Interventions: V-TRACTS Assessment/Feedback, OPTIONAL Brief Assessment of Thinking, OPTIONAL STEP-Home-Brief, OPTIONAL At-home Exercise Program, OPTIONAL Referral to 12-week STEP-Home, OPTIONAL Clinical Referral; Behavioral
Lead sponsor: VA Boston Healthcare System; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

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EXPAREL Dose-Response for Single-Injection Femoral Nerve Blocks

Efficacy of Belatacept in Reducing DSA

Double Dose 4-AP on Functional Recovery After Spinal Cord Injury

Human and Digital Support Study

Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project)

Blood Glucose Stability and Variability on Two Diets

Reducing Risk After an Adverse Pregnancy Outcome

Flu Vaccine in Preventing Influenza Infection in Healthy Volunteers and in Patients Who Have Undergone Stem Cell Transplant

Cabozantinib With Topotecan-Cyclophosphamide

StimRouter™ for Pain Management in Post-stroke Shoulder Pain

Transdiagnostic Group Therapy (GBAT) for Autistic Adults With Personalized Therapeutics

Efficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum Onset

National Program to Overcome Pelvic Pain studY (POPPY)

Well-Mama Community Doula Navigator Study

Technology-delivered Physical Activity Program for Adolescents With Type 1 Diabetes

The Personal Patient Profile Decision Support for Patients With Bladder Cancer

A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid Tumours

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Central Retinal or Hemiretinal Vein Occlusion

Nueva Vida Intervention for Latina Breast Cancer Survivors and Caregivers

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia

Tailored Anti-Inflammatory American Diet for Patients With Crohn's Disease

Acid-Base Composition With Use of hemoDialysates

Translational Research Center for TBI and Stress Disorders: Virtual Assessment of Deployment Trauma and Rehabilitation