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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers

Efficacy Long-term Dietary Nitrate Consumption to Plasma Nitrite Conversion

NCT05380167
Conditions
Cardiovascular Diseases in Old Age
Interventions
BRJ Nitrate, BRJ Placebo
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
40 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Terminated Early Phase 1 Interventional Accepts healthy volunteers Results available

Vascular Dysfunction in Black Individuals: Roles of Nitric Oxide and Endothelin-1

NCT04770155
Conditions
Vascular Function, Racial Disparity
Interventions
Dietary Nitrates 400 mg, L-citrulline 3 g, Sildenafil 100 mg, Bosentan 125 mg
Dietary Supplement · Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Jackson, Mississippi
Conditions
Post Traumatic Stress Disorder, Trauma
Interventions
Beetroot Juice, Placebo Juice
Dietary Supplement
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Nutraceuticals
Interventions
Betalain-rich concentrate (AltRed), Placebo
Dietary Supplement · Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Phase 2 Interventional Results available

Nitrite Supplementation in Long COVID Patients

NCT05618574
Conditions
Long COVID, Cardiorespiratory Fitness
Interventions
140 ml per day of Beet-It nitrate beverage (James White Drinks Ltd., Ipswich, UK), 210 ml of nitrate-depleted placebo
Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Not listed Phase 2 Interventional Accepts healthy volunteers

Beetroot Juice NO Cold Study

NCT06416228
Conditions
Respiratory Tract Infections, Cold Symptoms, Exhaled Nitric Oxide
Interventions
Beetroot juice
Dietary Supplement
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 30 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Dallas, Texas • Waco, Texas
Conditions
Cancer Survivor With History of Anthracycline Chemotherapy
Interventions
Beetroot juice, Black currant juice
Dietary Supplement
Lead sponsor
Kansas State University
Other
Eligibility
21 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Manhattan, Kansas
Conditions
Stroke, Ischemic Stroke, Cerebrovascular Accident
Interventions
Beet it Beetroot juice, Beet It Placebo Beetroot juice
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Metabolic Syndrome
Interventions
Beetroot Juice - Active, beetroot juice - Placebo
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
Metabolic Disease, Obesity, Exercise
Interventions
Sodium Nitrate, Beetroot Juice no Nitrate, Beetroot Juice
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 40 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Exercise Performance of Fit Athletes, Exercise Performance, Cycling Performance
Interventions
Dietary Nitrate, Caffeine, Placebo
Dietary Supplement · Other
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Saint Charles, Missouri
Completed Not applicable Interventional Accepts healthy volunteers

Inorganic Nitrate and OSA

NCT03930563
Conditions
Obstructive Sleep Apnea
Interventions
Pre-beetroot juice supplementation, Post-beetroot juice supplementation
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
30 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Stroke, CVA
Interventions
Beetroot Juice supplement, Placebo supplement
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 89 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Beetroot Supplementation in Women Enjoying Exercise Together

NCT04370756
Conditions
Aging, Postmenopause, Obesity
Interventions
Beetroot Juice, Exercise Training
Dietary Supplement · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Healthy
Interventions
concentrated beet root juice, Placebo beet root juice
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 34 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Beet Juice and Diet in Female Rowers

NCT06045845
Conditions
Dietary Habits, Nitrates, Exercise
Interventions
Beet Juice, Placebo
Dietary Supplement
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Lawrence, Kansas
Completed Not applicable Interventional Accepts healthy volunteers

The Influence of Beetroot Juice on Racial Disparities in Vascular Health

NCT05132556
Conditions
Blood Pressure, Racial Disparities, Cardiovascular Risk Factor
Interventions
Acute Beetroot Juice
Other
Lead sponsor
Georgia Southern University
Other
Eligibility
18 Years to 39 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Savannah, Georgia
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults

NCT07572266
Conditions
Aging, Aging Well, Healthy Aging
Interventions
Nitrate enriched beetroot juice, Nitrate depleted beetroot juice, 12 week of combined exercise training
Dietary Supplement · Other
Lead sponsor
Florida Institute for Human and Machine Cognition
Other
Eligibility
60 Years and older
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Pensacola, Florida
Conditions
Chronic Kidney Disease
Interventions
Nitrate-rich beetroot juice, Nitrate-depleted beetroot juice
Dietary Supplement
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
30 Years to 80 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boulder, Colorado
Conditions
Aging
Interventions
Beetroot Juice, Placebo Beetroot Juice
Dietary Supplement · Other
Lead sponsor
Marquette University
Other
Eligibility
60 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Prehypertension
Interventions
Nitric Oxide supplement, Placebo
Dietary Supplement
Lead sponsor
Neogenis Laboratories
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Beverly Hills, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dietary Nitrate and Physiological Aging

NCT02593305
Conditions
Aging
Interventions
Super Beets, Super Beets Placebo
Dietary Supplement
Lead sponsor
Darren P Casey
Other
Eligibility
18 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Recruiting Not applicable Interventional Accepts healthy volunteers

Beetroot Juice and Sleep

NCT05864521
Conditions
Healthy
Interventions
Active Beetroot Juice Supplement (aBRJ), Placebo Beetroot Juice Supplement (pBRJ)
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Respiratory Failure
Interventions
Nitrate Rich Beetroot Juice, Placebo
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
56 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina