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ClinicalTrials.gov public records Last synced Nov 4, 2026, 10:32 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 413 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Behavioral Activation treatment Clear all

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BREATHE program, Usual Care; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 40 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Diabetes Mellitus, Type 1
Interventions: Usual care, Collaborative care model (CoCM); Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Schizophrenia, Schizoaffective Disorder
Interventions: Recovery Oriented Cognitive Therapy (CT-R), Treatment as Usual; Behavioral · Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Post Traumatic Stress Disorder
Interventions: Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Processing Therapy, Repetitive Transcranial Magnet Stimulation (rTMS); Device · Behavioral
Lead sponsor: The University of Texas at Dallas; Other
Eligibility: 18 Years to 60 Years
Enrollment: 103 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Mental Health Wellness 1
Interventions: OptimalWork, Podcast Listening; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Depression, Bipolar Disorder, Anhedonia
Interventions: Behavioral Activation-Full, Behavioral Activation-Short, Bipolar Disorder Collaborative Care; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 21 Years to 65 Years · Female only
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Heart Failure, Depression
Interventions: Cognitive Behavior Therapy, Heart Failure Self-care Education; Behavioral · Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 30 Years and older
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Depression During Pregnancy
Interventions: Virtual reality behavioral activation; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Major Depressive Disorder
Interventions: Smartphone-delivered CBT for MDD; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression
Interventions: Limbix Spark, Psychoeducation; Device · Other
Lead sponsor: Limbix Health, Inc.; Industry
Eligibility: 13 Years to 21 Years
Enrollment: 227 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning, Chronic Medical Conditions, Chronic Medical Condition, Chronic Medical Illness, Posttraumatic Stress Disorder PTSD, Posttraumatic Stress Disorders, Posttraumatic Stress Symptoms, Posttraumatic Stress
Interventions: Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual, Structured Psychotherapy for Adolescents Responding to Chronic Stress - Individual; Behavioral
Lead sponsor: Anthony Vesco; Other
Eligibility: 8 Years to 18 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Traumatic Brain Injury
Interventions: Behavioral Activation, Treatment as Usual; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Schizophrenia, Smoking Cessation, Tobacco Use
Interventions: Active deep transcranial magnetic stimulation (dTMS), Sham dTMS; Device
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Cigarette Smoking
Interventions: Standard Treatment, Behavioral Activation Treatment for Smoking, Transdermal Nicotine Patch; Behavioral · Drug
Lead sponsor: University of Maryland, College Park; Other
Eligibility: 18 Years to 65 Years
Enrollment: 184 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: College Park, Maryland

Conditions: Stem Cell Transplant Patients
Interventions: ACTivate sessions; Behavioral
Lead sponsor: Anthony Sung, MD; Other
Eligibility: 18 Years to 80 Years
Enrollment: 476 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2031
U.S. locations: 2
States / cities: Kansas City, Kansas • Durham, North Carolina

Conditions: Chronic Kidney Diseases, Major Depressive Disorder, End Stage Kidney Disease (ESRD)
Interventions: Bupropion, Behavioral activation therapy, Placebo, Clinical Management; Drug · Behavioral · Other
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older
Enrollment: 201 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 4
States / cities: Stony Brook, New York • Dallas, Texas • Seattle, Washington

Conditions: Cancer Survivors
Interventions: assessments (questionnaires); Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 65 Years and older
Enrollment: 454 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Hyperlipidemia, Diabetes, Hypertension
Interventions: Telepharmacist intervention; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 85 Years
Enrollment: 4,078 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Newton, Massachusetts

Conditions: Depression, Opioid Use, Chronic Pain, Anxiety
Interventions: Electronic medical recorded clinical decision support [EMR CDS], Stepped opioid collaborative care model [CCM]; Behavioral
Lead sponsor: Ochsner Health System; Other
Eligibility: 18 Years and older
Enrollment: 490 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Dementia
Interventions: Active Caregiving: Enhancing Skills; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Smoking Cessation
Interventions: Delay time to first cigarette, Therapy; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Diabetes Mellitus, Type 2
Interventions: Diabetes Homelessness Medication Support Program in Spanish; Behavioral
Lead sponsor: Hennepin Healthcare Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Elevated Caregiver Strain, Dementia Caregiver, Caregiver Stress
Interventions: Caring Together, Savvy Caregiver; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mild Cognitive Impairment (MCI)
Interventions: Behavioral Activation (BA), Supportive Therapy (ST); Behavioral
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 65 Years and older
Enrollment: 221 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Search by objective public record fields.

Improving Patient-Centered Care Delivery Among Patients With Chronic Obstructive Pulmonary Disease

Testing an Integrated Care Model Trial

Effectiveness and Mechanisms of Recovery Oriented Cognitive Therapy

Novel Treatment of Emotional Dysfunction in Post Traumatic Stress Disorder (PTSD)

Digital Intervention to Promote Medical Trainee Well-being (OptimalWork Pilot)

Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder

Depression and Self-care in Heart Failure

Virtual Reality-enhanced Psychotherapy for Perinatal Depression

Waitlist-Control Trial of Smartphone CBT for Major Depressive Disorder (MDD)

A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19

Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress

ACTIVE: Activity Therapy to Increase Veteran Engagement

Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia

Behavioral Activation Intervention for Smoking Cessation in Smokers With Depressive Symptoms

ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant Patients

Combination of Novel Therapies for CKD Comorbid Depression

A Study of Counseling Support for Cancer Survivors Age 65+

Tele-Pharmacy Intervention to Improve Treatment Adherence

Opioid Treatment and Recovery Through a Safe Pain Management Program

The Black Immigrant Project

Neuroimaging Studies of Practice and Smoking

Diabetes Homelessness Medication Support Program in Spanish

Leveraging Interventions for Caregiver Growth, Health, Training, Empowerment and Navigation: Comparing Group Behavioral Interventions to Improve Dementia Caregiver Strain

Preventing Cognitive Decline in African Americans With Mild Cognitive Impairment