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Conditions: Nicotine Dependence
Interventions: Behavioral Counseling, Self-help control; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Tourette Syndrome, Tic Disorders
Interventions: Habit reversal therapy, Supportive therapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 16 Years and older
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 3
States / cities: New Haven, Connecticut • Boston, Massachusetts • San Antonio, Texas

Conditions: Grief, Trauma, Psychotherapy, Critical Care
Interventions: EMPOWER, Supportive Conversation; Behavioral · Other
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 172 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 3
States / cities: Miami, Florida • New York, New York

Conditions: Parental Language Behaviors
Interventions: Linguistic Feedback Report, Multimedia Education Sessions, EI-As-Usual; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 6 Months and older
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Depression
Interventions: Behavioral Activation Therapy, Treatment as Usual- Psychotherapy; Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 11 Years to 18 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Autism Spectrum Disorder
Interventions: Opt-In Early Latinx intervention, Opt-In Early Rural Intervention; Other
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 15 Months and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Hartford, Connecticut • Portland, Oregon

Conditions: Pain, Postoperative, Excavatum, Pectus, Scoliosis Idiopathic
Interventions: Meditation; Behavioral
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 8 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Attention Deficit Hyperactivity Disorder
Interventions: Brief Early Intervention, Parent Training with Adolescent Cognitive Behavioral Therapy, Methylphenidate; Behavioral · Drug
Lead sponsor: Florida International University; Other
Eligibility: 12 Years to 16 Years
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Developmental Delay, Disruptive Behavior
Interventions: Internet-delivered Parent-Child Interaction Therapy (I-PCIT), Referrals as Usual (RAU); Behavioral · Other
Lead sponsor: Florida International University; Other
Eligibility: 30 Months to 60 Months
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 3
States / cities: Miami, Florida • Palmetto Bay, Florida

Conditions: Type 1 Diabetes
Interventions: Team Clinic Care, Standard Care; Other
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: 10 Years to 17 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety, OCD, Phobia, Agoraphobia, Generalized Anxiety, Generalized Anxiety Disorder, Selective Mutism, Separation Anxiety, Social Anxiety, Social Anxiety Disorder, Panic Disorder, Pediatric Disorders
Interventions: Team-delivered, exposure-based CBT; Behavioral
Lead sponsor: Bradley Hospital; Other
Eligibility: 5 Years to 18 Years
Enrollment: 501 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: East Providence, Rhode Island

Conditions: Family Relations, Sibling Relations
Interventions: SIB-Time Web-Application Tool; Behavioral
Lead sponsor: Oregon Research Behavioral Intervention Strategies, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Interpersonal Violence
Interventions: Program for Alleviating Relationship Trauma and Stress through New Behaviors (PARTS-NB); Behavioral
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years and older · Male only
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 2
States / cities: Malden, Massachusetts • Tumwater, Washington

Conditions: Malignant Neoplasm
Interventions: Music Therapy, Psychosocial Assessment and Care, Quality-of-Life Assessment; Procedure · Other
Lead sponsor: Children's Oncology Group; Network
Eligibility: 11 Years to 24 Years
Enrollment: 118 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2021
U.S. locations: 3
States / cities: Atlanta, Georgia • Philadelphia, Pennsylvania

Conditions: Parent-Child Relations, Parenting Self Efficacy, Child Mental Health
Interventions: Project Support, Case Management Services; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 6 Years to 13 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: BRCA1 Mutation, POLD1 Gene Mutation, CDKN2A Mutation, BRCA2 Mutation, POLE Gene Mutation, APC Gene Mutation, ATM Gene Mutation, MLH1 Gene Mutation, BARD1 Gene Mutation, MSH2 Gene Mutation, BRIP1 Gene Mutation, MSH6 Gene Mutation, CHEK2 Gene Mutation, PMS2 Gene Mutation, PALB2 Gene Mutation, EPCAM Gene Mutation, RAD51C Gene Mutation, BMPR1A Gene Mutation, RAD51D Gene Mutation, SMAD4, PTEN Gene Mutation, GREM1
Interventions: Intervention Arm At-risk Relative/ARR Contacts, MyGene Portal, Standard of Care; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 25 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 8
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Obesity
Interventions: Team PLAY; Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 4 Years to 7 Years
Enrollment: 270 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Anorexia Nervosa
Interventions: Multi-Family Therapy; Behavioral
Lead sponsor: University of Illinois at Chicago; Other
Eligibility: 11 Years to 18 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Aggression Childhood, Teen Dating Violence
Interventions: Experimental: Intervention (SPARE) plus Treatment as Usual, Treatment as Usual (TAU); Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 11 Years to 13 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder, Obsessive-compulsive Disorder, Specific Phobia
Interventions: Cognitive Behavioral Therapy, Treatment as usual; Other
Lead sponsor: University of South Florida; Other
Eligibility: 6 Years to 12 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Internet Gaming Disorder
Interventions: Behavioral therapy, Referral for care; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 10 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Suicide Prevention
Interventions: Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP), Youth-Nominated Support Team; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 12 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Detroit, Michigan

Conditions: Tic Disorder, Childhood, Comorbidities and Coexisting Conditions
Interventions: Combination of Comprehensive Behavioral Intervention for Tics (CBIT) and Evidence-based interventions for co-occurring diagnoses (i.e., Cognitive Behavioral Therapy, Behavioral Parent Training); Behavioral
Lead sponsor: Florida International University; Other
Eligibility: 7 Years to 17 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Suicide
Interventions: Family-Based Crisis Intervention; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 13 Years to 18 Years
Enrollment: 143 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

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Counseling to Reduce Children's SHS Exposure: A Trial With Maternal Smokers

Effectiveness of Behavior Therapy and Psychosocial Therapy for the Treatment of Tourette Syndrome and Chronic Tic Disorder

A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients

Project ASPIRE Efficacy Pilot: Achieving Superior Parental Involvement for Rehabilitative Excellence

Behavioral Activation With Depressed Adolescents

Opt-In Early Pilot Study

Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery

Intervention for Teens With ADHD and Substance Use

Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program

Team Clinic: Virtual Expansion of an Innovative Multi-Disciplinary Care Model for Adolescents and Young Adults With Type 1 Diabetes

Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.

SIB-Time Web-application Tool for Typically Developing Siblings

Program for Alleviating and Reducing Trauma and Stress for Intimate Partner Violence

Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant

Examining Whether Project Support Works

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Team PLAY (Positive Lifestyles for Active Youngsters)

Investigation of Multi-Family Therapy for Anorexia Nervosa

Trauma-Informed Peer Aggression and Dating Violence Prevention for Preteens Receiving Intensive Mental Health Services

Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety

Reducing Internet Gaming

Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk

Improving Symptom Trajectories of Tic Disorders and Co-occurring Diagnoses: The Role of Integrative Intensive Intervention

Family-based Crisis Intervention With Suicidal Adolescents in the ED