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Conditions: Drug Addiction, Stimulant Dependence, Opiate Dependence, Alcohol Dependence, Substance Abuse
Interventions: Community Reinforcement and Family Training, Treatment Entry Training, 12- step Al/Nar- Anon Facilitation; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Substance Use Disorders, Recidivism
Interventions: Adolescent Community Reinforcement Approach, Assertive Continuing Care, Trauma Affect Regulation Guide for Education and Therapy, Motivational Interviewing, Opioid Education Workbook; Behavioral · Other
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 15 Years to 25 Years
Enrollment: 215 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Olympia, Washington

Conditions: Opioid Use Disorder
Interventions: MAT + A-CHESS, MAT; Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 417 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Pediatric Obesity
Interventions: Lifestyle intervention and carotenoid supplements, Lifestyle intervention and placebo; Other
Lead sponsor: Nemours Children's Clinic; Other
Eligibility: 8 Years to 11 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Klinefelter Syndrome
Interventions: Counseling; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years to 25 Years · Male only
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Alcohol Use Disorder, Family Members, Behavior, Addictive
Interventions: PartnerCHESS, ACHESS; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 398 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: PreDiabetes
Interventions: Online diabetes prevention program, Standard Care; Behavioral
Lead sponsor: Omada Health, Inc.; Industry
Eligibility: 19 Years and older
Enrollment: 598 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Substance Abuse, Substance Dependence
Interventions: Chestnut Bloomington Outpatient (CBOP), Motivational Enhancement Therapy/Cognitive Behavior Treatment (MET/CBT 7), Assertive Continuing Care (ACC); Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 12 Years to 18 Years
Enrollment: 320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Bloomington, Illinois

Conditions: Chronic Disease
Interventions: Counseling, Flyer; Behavioral
Lead sponsor: Sutter Health; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Colorectal Cancer
Interventions: TeleCARE, Pamphlet intervention; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 30 Years to 74 Years
Enrollment: 496 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 8
States / cities: Sacramento, California • Aurora, Colorado • Denver, Colorado + 3 more

Conditions: Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified, Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder
Interventions: Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 7 Years to 13 Years
Enrollment: 214 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Substance Use Disorders, Reproductive Issues, Contraception
Interventions: MyPath tool; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 1 participant
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Alcohol Abuse
Interventions: Standard Care, Multidimensional Family Therapy, Family Motivational Interviewing Intervention; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Years to 18 Years
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 3
States / cities: Miami, Florida

Conditions: Depressive Symptoms, Burden
Interventions: Social work support, Educational material, NYU caregiver counseling intervention, REACH OUT counseling intervention; Other · Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 221 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Diabetes, Obesity
Interventions: Lifestyle counseling; Behavioral
Lead sponsor: Vanderbilt University; Other
Eligibility: 3 Years to 5 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: HIV
Interventions: FAmily-CEntered Advance Care Planning, Healthy Living Control; Behavioral
Lead sponsor: Children's National Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 444 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 5
States / cities: Washington D.C., District of Columbia

Conditions: Gestational Diabetes Mellitus, Pre-diabetes
Interventions: Diabetes Prevention Program (DPP); Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 8 Years and older
Enrollment: 335 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Mental Health Issue, Parent-Child Relations
Interventions: LGBTQ-affirmative CBT, ABFT-SGM; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 20 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Crohn Disease
Interventions: Diet Counseling, CD LFD, Dyadic Psychological Support (DPS); Behavioral · Other
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 70 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Substance Use, Delinquency
Interventions: Multidimensional Family Therapy (MDFT), Adolescent Residential Treatment; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 13 Years to 17 Years
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2010
U.S. locations: 2
States / cities: Miami, Florida

Conditions: Obesity, Nutrition Poor, Physical Activity, Weight Loss
Interventions: Healthy Frio In-Person Family-focused Intervention, Healthy Frio Remote Technology Family-focused Intervention, Control; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 8 Years and older
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Pearsall, Texas

Conditions: BRCA1 Mutation, POLD1 Gene Mutation, CDKN2A Mutation, BRCA2 Mutation, POLE Gene Mutation, APC Gene Mutation, ATM Gene Mutation, MLH1 Gene Mutation, BARD1 Gene Mutation, MSH2 Gene Mutation, BRIP1 Gene Mutation, MSH6 Gene Mutation, CHEK2 Gene Mutation, PMS2 Gene Mutation, PALB2 Gene Mutation, EPCAM Gene Mutation, RAD51C Gene Mutation, BMPR1A Gene Mutation, RAD51D Gene Mutation, SMAD4, PTEN Gene Mutation, GREM1
Interventions: Intervention Arm At-risk Relative/ARR Contacts, MyGene Portal, Standard of Care; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 25 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 8
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Youths At-risk for Drug Use/Abuse
Interventions: Integrated Family and Cognitive-Behavioral Drug Prevention Intervention, Psychoeducation; Behavioral · Other
Lead sponsor: University of Florida; Other
Eligibility: 11 Years to 15 Years
Enrollment: 330 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Suicide, Suicide, Attempted
Interventions: In-person TASCS, Telehealth TASCS, Self-administered TASCS, Follow-up care; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Worcester, Massachusetts

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CRAFT Behavior Therapy: Treatment Entry Component

Preventing OUD in Justice-Involved Youth

Impact on Opioid Use of Bundling Medication-assisted Treatment With mHealth

Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity

Fertility Assessment in Patients With Klinefelter Syndrome

Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19

Preventing Diabetes With Digital Health and Coaching

Adolescent Outpatient and Continuing Care Study

Family Planning Counseling for Women With Chronic Medical Conditions in an Inpatient Setting

Family Colorectal Cancer Awareness and Risk Education Project (Family CARE Project)

Psychotherapy for Anxiety in Children With Autism Spectrum Disorder

Evaluating MyPath to Enhance Reproductive Autonomy and Liberate Decision-making

Family Intervention for Teen Drinking in the ER

Northern-Manhattan Hispanic Caregiver Intervention Effectiveness Study

ST of TN-Salud Con La Familia: Prevent Onset of Ped Obesity

Palliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care

Encourage Healthy Families

Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents

Diet Intervention for Crohn's Disease Patient

Family-based and Adolescent Residential Drug Treatment

Healthy Frio: A Rural Community Partnership to Advance Latino Obesity Research

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Neurological Influences on Drug Prevention Intervention

Technology-Assisted Systems Change for Suicide Prevention