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ClinicalTrials.gov public records Last synced Oct 4, 2026, 10:34 PM EDT

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Showing 25–48 of 182 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Behavioral weight control and lifestyle exercise Clear all
Recruiting Phase 4 Interventional

Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

NCT07058155
View directory record Official record
Conditions
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
Interventions
Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), Lifestyle Counseling - Diet & Physical-Activity Program
Procedure · Drug · Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Barriers to Effective Weight Loss in Overweight Adolescents

NCT00562263
View directory record Official record
Conditions
Overweight
Interventions
Lifestyle modification
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
11 Years to 18 Years · Female only
Enrollment
257 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional

Active Surveillance Exercise Clinical Trial

NCT02435472
View directory record Official record
Conditions
Localized Prostate Cancer, Active Surveillance for Prostate Cancer
Interventions
Exercise, Cardiopulmonary Exercise Test (CPET)
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 11, 2025 · Synced Oct 4, 2026, 10:34 PM EDT
Recruiting Not applicable Interventional

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

NCT05901675
View directory record Official record
Conditions
Obesity, Stroke
Interventions
Lifestyle Management Program, Post-stroke Optimization of Walking using Explosive Resistance
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
35 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Tailored Messages to Encourage Healthy Lifestyle Choices in a Brief, Self-directed Intervention

NCT06856551
View directory record Official record
Conditions
Weight Control
Interventions
Minimal contact control, Promotion and Prevention Interventions
Behavioral
Lead sponsor
University of North Florida
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional

Collaborate and Leverage Evidence in African American Rural Network

NCT06730633
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Heart Matters
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
9
States / cities
Enfield, North Carolina • Nashville, North Carolina • Rocky Mount, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Investigating the Effects of the "GameDay Ready" Behavioral Weight Management Program for Black Men Living in the Rural South

NCT05970042
View directory record Official record
Conditions
Obesity
Interventions
GameDay Ready, Walking and General Health Education
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
20 Years to 70 Years · Male only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Results available

Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach

NCT05104450
View directory record Official record
Conditions
Obesity, Sleep Apnea, Obstructive
Interventions
lifestyle intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
696 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional

Behavior Change Family Counseling to Reduce Rate of Weight Gain in At-Risk Children

NCT00241891
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Obesity
Interventions
Single behavior intervention, Multiple behavior interventions, Control Intervention unrelated to weight
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 12 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional

Lifestyle Intervention for Treatment of Diabetes

NCT01806727
View directory record Official record
Conditions
Type 2 Diabetes, Overweight, Obesity
Interventions
Community Lifestyle Weight Loss (LWL), Diabetes Self Management (DSM)
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
21 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 4, 2026, 10:34 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Weight and Shape Concern Among Women with High Body Weight

NCT05845866
View directory record Official record
Conditions
Body Image Disturbance, Overweight and Obesity, Weight Loss
Interventions
Modified Body Project, Facts about obesity, myths about weight loss, Lifestyle intervention for weight loss
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
25 Years to 70 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional

The Effects of a Pre-packaged, Portion Controlled Meal Plan on Type 2 Diabetes and Glycemic Control: A Comparison Study

NCT01260337
View directory record Official record
Conditions
Obesity
Interventions
Portion controlled diet, Diabetes Support and Education
Behavioral · Other
Lead sponsor
Temple University
Other
Eligibility
21 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2013 · Synced Oct 4, 2026, 10:34 PM EDT
Terminated Not applicable Interventional Results available

Increasing Cure Rate of Hepatitis C Therapy in Obese Hepatitis C Patients

NCT00871845
View directory record Official record
Conditions
Obesity, Insulin Resistance, Metabolic Syndrome, Hepatitis C
Interventions
Dietary and Lifestyle modification educational sessions
Behavioral
Lead sponsor
Hossam Kandil
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 5, 2018 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Results available

Healthy Lifestyles for Mentally Ill People Who Have Experienced Weight Gain From Their Antipsychotic Medications - 2

NCT01052714
View directory record Official record
Conditions
Diabetes, Obesity, Weight Gain
Interventions
Lifestyle Balance
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
3
States / cities
Long Beach, California • Sepulveda, California • West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eating Disorder Prevention Programs

NCT00042185
View directory record Official record
Conditions
Eating Disorders
Interventions
Dissonance Eating Disorder Prevention Program, Healthy Weight Intervention, Expressive Writing Control Condition
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
14 Years to 19 Years · Female only
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2007
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2013 · Synced Oct 4, 2026, 10:34 PM EDT
Recruiting Not applicable Interventional

Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification

NCT05766735
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Routine Care + Glycemic Excursion Minimization (RC+GEM), Routine Care (RC)
Behavioral · Other
Lead sponsor
Chiara Fabris, PhD
Other
Eligibility
30 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

The Effect of Adiposity on Muscle and Microvascular Function in HFpEF

NCT06930495
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction (HFPEF)
Interventions
Weight loss SOC Treatment with second generation anti-diabetic medications
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Enrolling by invitation Not applicable Interventional

To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years

NCT07387393
View directory record Official record
Conditions
Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus (T2DM), Overweight (BMI > 25), Weight Loss Trial
Interventions
PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Fayetteville, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Comparing Two Treatments That Both Target Smoking Cessation and Weight Loss at the Same Time.

NCT04130698
View directory record Official record
Conditions
Smoking Cessation, Weight Loss
Interventions
Distress Tolerance, transdermal nicotine patch, Active Health Control
Behavioral · Drug
Lead sponsor
Rhode Island College
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Results available

ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss

NCT02518685
View directory record Official record
Conditions
Obesity
Interventions
TransPyloric Shuttle, Sham procedure, Lifestyle Counseling
Device · Behavioral
Lead sponsor
BaroNova, Inc.
Industry
Eligibility
22 Years to 60 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
9
States / cities
Scottsdale, Arizona • San Diego, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional

Healthy Lifestyles After Cancer for Adolescents and Young Adults: A Program to Reduce Cardiovascular Risk Factors

NCT05869604
View directory record Official record
Conditions
Cancer, Cardiovascular Diseases, Weight Management, Pain, Fatigue, Distress, Emotional, Physical Inactivity
Interventions
HEALTHY AYA, Education Control
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 39 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional

Longitudinal Effects of a Commercial Digital Weight Management Program on Weight Loss

NCT06666842
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Noom Weight, Educational Control
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
412 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Oct 4, 2026, 10:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Lifestyle Intervention for Healthy Change

NCT05956574
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Nutrigenomix, personalized dietary plan, Physical Activity, Behavioral counseling, Standard Dietary plan
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 40 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional

Smart Technology for Weight Loss and Metabolic Health

NCT02742662
View directory record Official record
Conditions
Obesity, Overweight, Prediabetes, Weight Loss, Lifestyle
Interventions
Wearable technology, smartscale, Smartphone applications, Standard Weight Management Visits
Device · Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 15, 2018 · Synced Oct 4, 2026, 10:34 PM EDT