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ClinicalTrials.gov public records Last synced Oct 13, 2026, 4:32 PM EDT

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Showing 193–216 of 386 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Behavioral weight loss treatment Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Keeping Weight Off: Brain Changes Associated With Healthy Behaviors

NCT02189187
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Mindfulness, Psychoeducation
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
25 Years to 60 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Oct 13, 2026, 4:32 PM EDT
Terminated Phase 3 Interventional

A 14-Month Study On The Effects Of CP-945,598 For The Prevention Of Weight Regain In Obese Patients

NCT00483171
View directory record Official record
Conditions
Obesity
Interventions
CP-945,598, Non-pharmacological weight loss program (NPP), Low Calorie Diet
Drug · Behavioral
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
699 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
La Jolla, California • Denver, Colorado • Baton Rouge, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2012 · Synced Oct 13, 2026, 4:32 PM EDT
Terminated Not applicable Interventional Results available

Diet and Exercise Program to Promote Weight Loss and Improve Health in Men With Low- or Low-Intermediate-Risk Prostate Cancer

NCT02454517
View directory record Official record
Conditions
Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC V7, Stage IIA Prostate Cancer AJCC v7
Interventions
Behavioral Dietary Intervention, Exercise Intervention, Informational Intervention, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
40 Years and older · Male only
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Oct 13, 2026, 4:32 PM EDT
Recruiting Not applicable Interventional

Motivating Increases in Physical Activity for Prevention of Weight Regain After Metabolic Bariatric Surgery

NCT06484621
View directory record Official record
Conditions
Obesity
Interventions
Acceptance and Commitment Therapy-Based Physical Activity Intervention, Physical Activity Education Control
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 13, 2026, 4:32 PM EDT
Not yet recruiting Phase 1 Interventional

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

NCT07224087
View directory record Official record
Conditions
Obesity, Smoking Cessation, Bariatric Surgery Patients
Interventions
Naltrexone Hydrochloride, Bupropion HCl Extended Release, Cognitive-Behavioral Therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Safety and Efficacy of Low and High Carbohydrate Diets

NCT00143936
View directory record Official record
Conditions
Obesity
Interventions
Low- Carbohydrate -Atkins Diet, Low Calorie Diet
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
3
States / cities
Denver, Colorado • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 15, 2010 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Not applicable Interventional

Peer-enhanced Intervention to Support Teen Weight Loss

NCT00285558
View directory record Official record
Conditions
Obesity
Interventions
CBT with peer-enhanced activities, CBT with supervised aerobic exercise
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
13 Years to 16 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Not applicable Interventional

Mood and Nutrition Interventions in Polycystic Ovary Syndrome

NCT01899001
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS)
Interventions
Cognitive Behavioral Therapy, Nutrition Counseling
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2016 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Not applicable Interventional

EMPOWER Men to Reduce Weight and Inhibit Prostate Cancer Progression

NCT04266431
View directory record Official record
Conditions
Prostatic Neoplasm
Interventions
EMPOWER
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Not applicable Interventional

Lifestyle Intervention to Improve Bone Quality

NCT03329963
View directory record Official record
Conditions
Aging, Obesity
Interventions
Healthy Lifestyle Intervention, Lifestyle Intervention
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Not applicable Interventional

Using a State-wide Initiative to Disseminate Effective Behavioral Weight Loss Strategies: Study 5

NCT02163252
View directory record Official record
Conditions
Obesity
Interventions
Standard, Early Intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 19, 2015 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)

NCT04599504
View directory record Official record
Conditions
Loss-of-control Eating, Obesity/Overweight
Interventions
Lisdexamfetamine Dimesylate (Medication), Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 64 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Personalized vs. Standard Approach to Weight Loss Recommendations

NCT04639076
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss Program, Personalized Behavioral Weight Loss Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
20 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 13, 2026, 4:32 PM EDT
Not yet recruiting Not applicable Interventional

Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online)

NCT07856784
View directory record Official record
Conditions
Binge Eating, Overweight and Obesity, Eating Disorders in Adolescence
Interventions
Cognitive-Behavioral Therapy for Adolescent Binge Eating, Lifestyle Behavioral Obesity Intervention, Active Control
Behavioral · Other
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 17 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 13, 2026, 4:32 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining Valence-based Effects in Self-Monitoring Feedback Messages

NCT07292389
View directory record Official record
Conditions
Obesity & Overweight, Obesity (Disorder)
Interventions
Positive Reinforcement, Positive Reinforcement + Areas for Change
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Not applicable Interventional Results available

Pilot of Lifestyle and Asthma Intervention

NCT03291808
View directory record Official record
Conditions
Asthma
Interventions
Weight loss intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Tucson, Arizona • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Phase 1 Interventional

Behavior Therapy Prior to Bariatric Surgery

NCT01125397
View directory record Official record
Conditions
Obesity
Interventions
LEARN group
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
25 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 10, 2013 · Synced Oct 13, 2026, 4:32 PM EDT
Active, not recruiting Not applicable Interventional

Miro-randomized Trial for Optimizing a JITAI to Reduce Dietary Lapses in Obesity Treatment

NCT04784585
View directory record Official record
Conditions
Obesity
Interventions
JITAI Enhanced Education Intervention Option, JITAI Self-Efficacy Intervention Option, JITAI Motivation Intervention Option, JITAI Self-Regulation Intervention Option, JITAI Generic Risk Alert Intervention Option (Active Comparator), Online Behavioral Obesity Treatment, JITAI No Treatment Intervention Option
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Not applicable Interventional

Dyad Plus Effectiveness/Feasibility

NCT04036331
View directory record Official record
Conditions
Weight Loss, Pediatric Obesity, Overweight Adolescents, Parent-Child Relations, Family and Household
Interventions
Brenner FIT Standard, By Design Essentials, Dyad Plus
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 13, 2026, 4:32 PM EDT
Active, not recruiting Not applicable Interventional

Becoming United in Lifestyle Decisions

NCT05796141
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Core Behavioral Weight Loss (BWL) intervention, Dyadic Action Planning, Joint Feedback, Autonomy Support Training, Home Environment Modifications
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 75 Years
Enrollment
762 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Phase 2 Interventional Results available

Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome

NCT02311673
View directory record Official record
Conditions
Prader-Willi Syndrome
Interventions
Setmelanotide, Placebo
Drug
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Eligibility
16 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
5
States / cities
Irvine, California • Gainesville, Florida • Kansas City, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 13, 2026, 4:32 PM EDT
Recruiting Not applicable Interventional

Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans

NCT07450118
View directory record Official record
Conditions
Prediabetes
Interventions
National Diabetes Prevention Program (DPP), Sleep Health Digital Application, Time-Restricted Eating (TRE)
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 13, 2026, 4:32 PM EDT
Completed Not applicable Interventional

Development of a Telehealth Obesity Intervention for Patients With MS: Modifying Diet and Exercise in MS

NCT04255953
View directory record Official record
Conditions
Multiple Sclerosis, Obesity
Interventions
behavioral telehealth, Treatment as Usual
Behavioral · Other
Lead sponsor
Jared Bruce
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Oct 13, 2026, 4:32 PM EDT
Completed No phase listed Observational

Study of Physical and Mental Health of Older Patients With Newly Diagnosed Cancer

NCT00769951
View directory record Official record
Conditions
Cognitive/Functional Effects, Depression, Hematopoietic/Lymphoid Cancer, Malnutrition, Pain, Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
Interventions
medical chart review, questionnaire administration, cognitive assessment, psychosocial assessment and care, quality-of-life assessment
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
65 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Oct 13, 2026, 4:32 PM EDT