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ClinicalTrials.gov public records Last synced Oct 3, 2026, 10:56 AM EDT

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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Bilevel positive airway pressure ventilation Clear all
Completed Not applicable Interventional Results available

Positive Airway Pressure for the Treatment of Asthma

NCT01154699
View directory record Official record
Conditions
Asthma, Sleep Apnea
Interventions
Bilevel PAP (4 weeks), Usual Care (4 weeks), Washout Period (4 weeks)
Device · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

EIT Assessment of Lung Volume and Tidal Distribution: A Comparison of Non-Invasive Ventilation Devices

NCT02930174
View directory record Official record
Conditions
Spontaneous Ventilation
Interventions
noninvasive positive pressure ventilation
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced Oct 3, 2026, 10:56 AM EDT
Completed No phase listed Observational Results available

Third International Study on Mechanical Ventilation

NCT01093482
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Not listed
Lead sponsor
Hospital Universitario Getafe
Other
Eligibility
18 Years and older
Enrollment
8,151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
18
States / cities
Iowa City, Iowa • Louisville, Kentucky • Boston, Massachusetts + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2018 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Servo-Ventilation In-lab PSG Evaluation

NCT02808338
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Philips BiPAP AutoSV Advanced System One, Modified Philips BiPAP ASV, ResMed S7 VPAP Adapt, ResMed S9 VPAP Adapt
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 3, 2026, 10:56 AM EDT
Recruiting Phase 2 Interventional

A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

NCT07071935
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS), Chronic Respiratory Failure, Neuromuscular Disease Patients, Neuromuscular Disease, Respiratory Insufficiency, Respiratory Insufficiency Requiring Mechanical Ventilation, Positive Pressure Ventilation, Non-invasive Ventilation, Non-invasive Ventilation Support, Non-invasive Ventilatory Support
Interventions
Non-invasive ventilation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Hershey, Pennsylvania • Philadelphia, Pennsylvania • Philadelphi, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Bipap Automatic Servo Ventilation (autoSV) Advanced in Central Apnea Patients

NCT01199042
View directory record Official record
Conditions
Cheyne-Stokes Respiration, Sleep Apnea, Central
Interventions
BiPAP autoSV Advanced
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
Wallingford, Connecticut • Louisville, Kentucky • Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 28, 2016 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Adaptive Servoventilation (ASV) in Patients With Central Sleep Apnea Due to Chronic Opioid Use

NCT01462084
View directory record Official record
Conditions
Obstructive Sleep Apnea, Central Sleep Apnea (Diagnosis), Chronic Opioid Use
Interventions
Adaptive servo-ventilation (ASV), Bi-Level PAP
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 3, 2026, 10:56 AM EDT
Completed No phase listed Observational

Use of Oxygen Hoods in Patients Failing on Conventional High-flow Oxygen Delivery Systems, Effects on Oxygenation in Hypoxic COVID-19 Patients. Prospective Cohort Study.

NCT04407260
View directory record Official record
Conditions
COVID -19, Respiratory Failure, Hypoxia
Interventions
Oxygen Hood
Device
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Sleepy Hollow, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2022 · Synced Oct 3, 2026, 10:56 AM EDT
Terminated Not applicable Interventional Results available

Bi-Level Positive Airway Ventilation for Acute Chest Syndrome

NCT01589926
View directory record Official record
Conditions
Sickle Cell Anemia, Acute Chest Syndrome
Interventions
Bi-level positive airway pressure device, Sham CPAP
Device
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
4 Years to 21 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Oct 3, 2026, 10:56 AM EDT
Terminated Not applicable Interventional

NIV for COPD: Hospital to Home

NCT04413643
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive, Noninvasive Ventilation
Interventions
Noninvasive Ventilation
Device
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Adherence and Therapeutic Effectiveness of Bi-Flex Versus CPAP in Children With OSA

NCT00458406
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Bi-Flex, CPAP
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years to 16 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Oct 3, 2026, 10:56 AM EDT
Recruiting Not applicable Interventional

WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department

NCT07558265
View directory record Official record
Conditions
Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
Interventions
Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
6
States / cities
Tucson, Arizona • Ann Arbor, Michigan • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

High Intensity Non-Invasive Positive Pressure Ventilation (HINPPV)

NCT01214200
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Bilevel positive airway pressure (BiPAP)
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
Up to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 2, 2019 · Synced Oct 3, 2026, 10:56 AM EDT
Recruiting Not applicable Interventional

Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

NCT07582211
View directory record Official record
Conditions
Pediatric Asthma, Acute Asthma, BiPAP, Non-invasive Positive Pressure Ventilation
Interventions
Bilevel positive airway pressure ventilation
Device
Lead sponsor
Columbia University
Other
Eligibility
5 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
New York, New York • Columbus, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Philips Respironics BiPAP autoSV Devices in Subjects With Sleep Disorders

NCT01626989
View directory record Official record
Conditions
Sleep Disordered Breathing, Sleep Apnea, Central
Interventions
BiPAP auto Advanced, BiPAP auto SV4
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
3
States / cities
Little Rock, Arkansas • Portage, Michigan • Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

High Flow Therapy for the Treatment of Respiratory Failure in the ED

NCT02236559
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Noninvasive positive pressure ventilation (NIPPV), Vapotherm
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
5
States / cities
Athens, Georgia • Florence, South Carolina • Chattanooga, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Software Enhancements to the Respironics BiPAP Auto Servo Ventilation (AutoSV) Device

NCT00720213
View directory record Official record
Conditions
Sleep Disordered Breathing, Sleep Apnea, Central
Interventions
Respironics BiPAP autoSV2, Respironics BiPAP autoSV3
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
5
States / cities
Tucson, Arizona • Little Rock, Arkansas • Portage, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Oct 3, 2026, 10:56 AM EDT
Recruiting Phase 2 Interventional

The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)

NCT05237505
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Overlap Syndrome
Interventions
bi-level positive pressure non invasive ventilation, Oxygen gas
Device · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 79 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional

Trial of Non-invasive Ventilation for Stable COPD

NCT01722773
View directory record Official record
Conditions
COPD
Interventions
Bipap (Respironics, Inc)
Device
Lead sponsor
University of Iowa
Other
Eligibility
35 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 7, 2012 · Synced Oct 3, 2026, 10:56 AM EDT
Terminated Not applicable Interventional Results available

Implementation of Nasal Non-Invasive Ventilation With a RAM Cannula in the Inpatient /Outpatient Setting

NCT03473171
View directory record Official record
Conditions
Chronic Respiratory Failure
Interventions
Nasal non-invasive ventilation with RAM cannula
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
1 Day to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Oct 3, 2026, 10:56 AM EDT
Not listed Phase 3 Interventional

Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome

NCT01427673
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overlap Syndrome
Interventions
Bipap procedure
Procedure
Lead sponsor
United States Air Force
Federal
Eligibility
35 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Wpafb, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 1, 2011 · Synced Oct 3, 2026, 10:56 AM EDT
Completed No phase listed Observational

CTTI Risk Factors for HABP/VABP Study

NCT02689531
View directory record Official record
Conditions
Pneumonia, Ventilator-Associated, Pneumonia, Bacterial, Pneumonia, Hospital-Acquired
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
7,530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • Chicago, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 3, 2026, 10:56 AM EDT
Terminated Not applicable Interventional Results available

The Role of Sleep Disordered Breathing in Heart Failure Admissions

NCT02505867
View directory record Official record
Conditions
Sleep Apnea Syndromes, Heart Failure
Interventions
Adaptive Servo Ventilation
Device
Lead sponsor
Rami Khayat
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Oct 3, 2026, 10:56 AM EDT
Withdrawn Not applicable Interventional

Noninvasive Positive Airway Pressure in the Pediatric Emergency Department for the Treatment of Acute Asthma Exacerbations

NCT01497691
View directory record Official record
Conditions
Asthma
Interventions
NIPPV (PALMtop PTV), Volumetric CO2 (NM3), USCOM
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
2 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Oct 3, 2026, 10:56 AM EDT