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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:40 PM EDT

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Showing 313–336 of 808 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Biomarker Testing Clear all
Active, not recruiting No phase listed Observational

Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial

NCT04565119
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
No intervention. This is an observational study.
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 6:40 PM EDT
Withdrawn No phase listed Observational

Determination of Assay Cut-Off for the RadTox Test in Prostate Cancer Patients to Predict GI Radiation Toxicity

NCT04580667
View directory record Official record
Conditions
Prostate Cancer
Interventions
Collection of plasma samples
Other
Lead sponsor
DiaCarta, Inc.
Industry
Eligibility
30 Years to 85 Years · Male only
Timeline
2020 – 2023
U.S. locations
5
States / cities
Gainesville, Florida • Jacksonville, Florida • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Oct 21, 2026, 6:40 PM EDT
Completed Not applicable Interventional

Using Biomarkers to Optimize Antibiotic Strategies in Sepsis

NCT02207114
View directory record Official record
Conditions
Sepsis
Interventions
Biomarker Algorithm Intervention
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 5, 2024 · Synced Oct 21, 2026, 6:40 PM EDT
Completed Not applicable Interventional

Improving Sexually Transmitted Infection (STI) Results Notification and Partner Services

NCT01938053
View directory record Official record
Conditions
Sexually Transmitted Infections
Interventions
Call when test results are ready, Text message when test results are ready, Call and text message when test results are ready
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
14 Years to 21 Years
Enrollment
609 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 21, 2026, 6:40 PM EDT
Completed Not applicable Interventional Results available

Lactobacillus Rhamnosus GG in Reducing Incidence of Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant

NCT02144701
View directory record Official record
Conditions
Graft Versus Host Disease
Interventions
Lactobacillus rhamnosus GG, laboratory biomarker analysis was not performed because of no differences in the clinical outcomes
Dietary Supplement · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 21, 2026, 6:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Sabroxy™ (Oroxylum Indicum Extract) for Improving Cognitive Function in Adults With Mild Memory Concerns

NCT07189754
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Cognitive Dysfunction, Cognitive Disorder, Memory Problems
Interventions
Sabroxy™ (Oroxylum indicum extract), Placebo
Dietary Supplement · Other
Lead sponsor
SF Research Institute, Inc.
Network
Eligibility
60 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Oct 21, 2026, 6:40 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Event-Related Potential (ERP) Biomarkers in Subjects With Schizophrenia and Healthy Volunteer Subjects

NCT04025502
View directory record Official record
Conditions
Schizophrenia
Interventions
Event-Related Potentials (ERP) and Electroencephalogram (EEG) testing with the COGNISION® System
Device
Lead sponsor
ERP Biomarker Qualification Consortium
Industry
Eligibility
21 Years to 50 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
4
States / cities
Garden Grove, California • Torrance, California • Marlton, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Oct 21, 2026, 6:40 PM EDT
Completed No phase listed Observational

Efficacy and Utility of Cxbladder Tests in Hematuria Patients

NCT04943380
View directory record Official record
Conditions
Hematuria, Urothelial Carcinoma
Interventions
Cxbladder
Diagnostic Test
Lead sponsor
Pacific Edge Limited
Industry
Eligibility
18 Years and older
Enrollment
682 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
10
States / cities
San Diego, California • Bay Pines, Florida • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 21, 2026, 6:40 PM EDT
Completed No phase listed Observational

Perioperative Kinetics of Reactive Hyperemia Using Noninvasive Digital Thermal Monitoring

NCT00683150
View directory record Official record
Conditions
Abdominal Surgery, Thoracic Surgery
Interventions
Endothelial Function Test
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2012 · Synced Oct 21, 2026, 6:40 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

PRESEPT Study: Evaluation of SEPT9 Biomarker Performance for Colorectal Cancer Screening

NCT00855348
View directory record Official record
Conditions
Colorectal Cancer
Interventions
All eligible subjects will provide blood for SEPT9 biomarker testing
Other
Lead sponsor
Epigenomics, Inc
Industry
Eligibility
50 Years and older
Enrollment
7,929 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
20
States / cities
Boca Raton, Florida • Miami, Florida • Atlanta, Georgia + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2014 · Synced Oct 21, 2026, 6:40 PM EDT
Recruiting Not applicable Interventional

Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety: R33 Phase

NCT07818876
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Cognitive Bias Modification for Interpretations (CBM-I), Cognitive Restructuring (CR)
Other
Lead sponsor
University of Denver
Other
Eligibility
10 Years to 17 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 21, 2026, 6:40 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Investigating the Diagnostic Potential of Tear Proteins in Cancer - A Pilot Study

NCT05223218
View directory record Official record
Conditions
Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Melanoma
Interventions
Schirmer strip, a Class I Medical Device typically used to test for dry eye.
Other
Lead sponsor
Namida Lab
Industry
Eligibility
18 Years to 100 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 21, 2026, 6:40 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Normative Values for Cognitive Testing and Alzheimer's Imaging Biomarkers in Young Adults

NCT01609335
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
F-18 FDG, C-11 PiB
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 49 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 8, 2014 · Synced Oct 21, 2026, 6:40 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Validating Imaging Biomarkers of Small Vessel Disease in Diabetic Individuals Using Advanced MRI Techniques.

NCT03754608
View directory record Official record
Conditions
Small Vessel Disease of Diabetes Mellitus
Interventions
MRI including cf-MRI, DTI, ASL and CVR.
Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
55 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Oct 21, 2026, 6:40 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Biomarkers in Friedreich's Ataxia

NCT02497534
View directory record Official record
Conditions
Friedreich's Ataxia
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
6 Years to 70 Years
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 6:40 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

BioFINDER-Brown: Examination of Alzheimer's Disease Biomarkers

NCT05457998
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Dementia
Interventions
Flutemetamol F18 Injection, [18F]-RO6958948 Injection, [18F]-MK-6240 Injection
Diagnostic Test
Lead sponsor
Butler Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Oct 21, 2026, 6:40 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Exertional Heat Illness: Biomarkers for Prediction and Return to Duty

NCT01434979
View directory record Official record
Conditions
Heat Illness
Interventions
Not listed
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 11, 2019 · Synced Oct 21, 2026, 6:40 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Informed Decision Making Intervention in Screening for Prostate Cancer of Predominantly African American Participants in a Community Outreach Program

NCT02419846
View directory record Official record
Conditions
Prostate Carcinoma
Interventions
Educational Intervention, digital rectal examination, Pre-test administration, Survey Administration, Prostate-specific antigen measurement, Post test administration
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Male only
Enrollment
319 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Oct 21, 2026, 6:40 PM EDT
Completed No phase listed Observational

Biomarker Analysis for Patients With Metastatic Colorectal Cancer (MCC)

NCT01909362
View directory record Official record
Conditions
Colorectal Neoplasms, Advanced Metastatic Colorectal Cancer
Interventions
Not listed
Lead sponsor
US Oncology Research
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Incl Greenville, SC and Tyler, TX, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2014 · Synced Oct 21, 2026, 6:40 PM EDT
Recruiting Not applicable Interventional

Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers

NCT03683680
View directory record Official record
Conditions
Mesothelioma
Interventions
MPT Test, CLDN15/VIM Test
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 21, 2026, 6:40 PM EDT
Recruiting Phase 1 Interventional

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

NCT05857969
View directory record Official record
Conditions
Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Large Cell Lymphoma, Refractory Childhood Acute Lymphoblastic Leukemia, Refractory Childhood Hodgkin Lymphoma, Refractory Childhood Malignant Germ Cell Neoplasm, Recurrent Childhood Brain Tumor, Recurrent Childhood Brainstem Glioma, Recurrent Childhood Rhabdomyosarcoma, Recurrent Childhood Soft Tissue Sarcoma, Recurrent Childhood Ependymoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Gliosarcoma, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Childhood Malignant Solid Neoplasm, Recurrent Childhood Malignant Solid Neoplasm, Recurrent Childhood Malignant Neoplasm, Refractory Childhood Malignant Neoplasm
Interventions
Functional Precision Medicine
Device
Lead sponsor
Florida International University
Other
Eligibility
1 Day to 21 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 21, 2026, 6:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Early Detection of Lung Cancer in a High-Risk Population Defined by PFT, Biomarkers, and CT Scanning

NCT00596310
View directory record Official record
Conditions
Lung Cancer
Interventions
CT
Other
Lead sponsor
Susanne Arnold
Other
Eligibility
55 Years to 75 Years
Enrollment
531 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2020
U.S. locations
4
States / cities
Hazard, Kentucky • Morehead, Kentucky • Prestonsburg, Kentucky + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 21, 2026, 6:40 PM EDT
Completed Not applicable Interventional

Biomarkers in the Diagnosis and Assessment of Pulmonary Arterial Hypertension (PAH)

NCT00566423
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Blood draw
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2011 · Synced Oct 21, 2026, 6:40 PM EDT
Recruiting No phase listed Observational

Clinicopathologic and Ancillary Testing of Primary Clear Cell Carcinoma of the Cervix

NCT05046080
View directory record Official record
Conditions
Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type
Interventions
Electronic Health Record Review, Laboratory Biomarker Analysis
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 21, 2026, 6:40 PM EDT