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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Bipolar education Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Decoding Emotional Dynamics in Bipolar Disorder

NCT07221864
View directory record Official record
Conditions
Bipolar Disorder I or II, Healthy (Controls)
Interventions
Think and Regulate Affective State Task
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 25, 2026, 1:35 PM EDT
Enrolling by invitation No phase listed Observational

Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models

NCT06792175
View directory record Official record
Conditions
Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD), Attention Deficit Hyperactivity Disorder (ADHD), Schizophrenia Spectrum &Amp; Other Psychotic Disorders, Post Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions
Solicue Machine Learning Models, Mercuria Machine Learning Models
Diagnostic Test
Lead sponsor
Psyrin Inc.
Industry
Eligibility
13 Years to 60 Years
Enrollment
500 participants
Timeline
2025 – 2026
U.S. locations
2
States / cities
Brookline, Massachusetts • Zanesville, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tailored Health Self-Management Interventions for Highly Distressed Family Caregivers

NCT03023332
View directory record Official record
Conditions
Distress, Caregiver
Interventions
Resourcefulness Training, Biofeedback training, Bipolar Education
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 120 Years
Enrollment
310 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Sep 25, 2026, 1:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression

NCT00075296
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 25, 2026, 1:35 PM EDT
Not yet recruiting No phase listed Observational

Overdose Prevention Centers and Behavioral Health

NCT06236087
View directory record Official record
Conditions
Overdose
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
500 participants
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Mindfulness Based Cognitive Therapy for Youth With Anxiety at Risk for Bipolar Disorder

NCT02090595
View directory record Official record
Conditions
Anxiety, Bipolar Disorder
Interventions
MBCT-C, Waitlist Control
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
10 Years to 17 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 17, 2016 · Synced Sep 25, 2026, 1:35 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Early Intervention for Youth at High Risk for Bipolar Disorder

NCT04815239
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Interpersonal and Social Rhythm Therapy (IPSRT), The Healthy Lifestyle Behavior Intervention (HL)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Phase 3 Interventional

Sleep Disturbance and Bipolar Disorder

NCT00993850
View directory record Official record
Conditions
Bipolar Disorder, Dyssomnias
Interventions
Cognitive behavioral therapy for insomnia, Bipolar education
Behavioral · Other
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2013 · Synced Sep 25, 2026, 1:35 PM EDT
Not listed Not applicable Interventional

Internet-Based Interventions for Bipolar Disorder

NCT02106078
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Moderated Discussion Board, Psychoeducation, Interactive Psychosocial Tools
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
21 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2015 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Project MOVE Bipolar

NCT07767032
View directory record Official record
Conditions
Bipolar Disorder (BD)
Interventions
BA, SHE, HE, CBEX
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Pilot Study of Interpersonal and Social Rhythm Therapy for Subthreshold Bipolar

NCT01520129
View directory record Official record
Conditions
Bipolar Disorder NOS
Interventions
Interpersonal and social rhythm therapy
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS)

NCT05683431
View directory record Official record
Conditions
Bipolar Disorder, Bipolar I Disorder, Bipolar Affective Disorder, Bipolar Disorder I, Bipolar Depression
Interventions
Cognitive Control of Emotion (CCE) Training
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 30 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Sep 25, 2026, 1:35 PM EDT
Completed No phase listed Observational

Perspectives of Individuals With Bipolar Disorder and Siblings of Individuals With Bipolar Disorder; A Telephone Interview Study

NCT00300820
View directory record Official record
Conditions
Bipolar Disorder (BD), Bipolar
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Training for Addressing Perinatal Depression

NCT04919967
View directory record Official record
Conditions
Mood Disorders, Anxiety Disorders
Interventions
Virtual implementation protocol, e-learning toolkit
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Leominster, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional Results available

Customized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder

NCT00763919
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Psychoeducation module, Substance abuse module, Improved communication/rapport with provider module, Medication routines management module
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2014 · Synced Sep 25, 2026, 1:35 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

End Diagnostic Overshadowing

NCT06608758
View directory record Official record
Conditions
Disabilities Multiple
Interventions
Electonic health record prompts with education, Standard of care
Behavioral · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
3 Years to 89 Years
Enrollment
120,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Phase 4 Interventional Results available

Treatment of Alcohol Dependence and Comorbid Bipolar Disorder

NCT01015586
View directory record Official record
Conditions
Alcohol Dependence, Bipolar Disorder, Depression, Mania, Psychosis
Interventions
Lamotrigine, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Sep 25, 2026, 1:35 PM EDT
Recruiting Not applicable Interventional

Suicidal Behavior in Patients Diagnosed With Bipolar Disorder

NCT02604277
View directory record Official record
Conditions
Depression, Alcoholism, Drug Abuse
Interventions
Interpersonal and Social Rhythm Therapy (ISRT), Bipolar-Specific Cognitive Behavioral Therapy (CBT), Mindfulness-Based Stress Reduction (MBSR), Psycho-education & Understanding Bipolar Medications Therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 64 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 25, 2026, 1:35 PM EDT
Recruiting No phase listed Observational

Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study

NCT06897670
View directory record Official record
Conditions
Major Depressive Disorder, Bipolar Disorder, Mild Cognitive Impairment
Interventions
Observational assessment using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable brain imaging tool that measures changes in brain blood flow and oxygen levels.
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Timeline
2025 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 25, 2026, 1:35 PM EDT
Recruiting No phase listed Observational

mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders

NCT06204705
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Early Intervention for Youth at Risk for Bipolar Disorder

NCT01483391
View directory record Official record
Conditions
Bipolar Disorder, Major Depressive Disorder
Interventions
Enhanced Care, Family-Focused Treatment
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
9 Years to 17 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
3
States / cities
Los Angeles, California • Stanford, California • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 3, 2021 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder

NCT02494050
View directory record Official record
Conditions
Depression, Bipolar Disorder, Anhedonia
Interventions
Behavioral Activation-Full, Behavioral Activation-Short, Bipolar Disorder Collaborative Care
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Treatment Adherence Enhancement in Bipolar Disorder

NCT01542008
View directory record Official record
Conditions
Treatment Noncompliance, Bipolar Disorder
Interventions
Customized Adherence Enhancement (CAE), broadly-directed, non-individualized education (EDU)
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 13, 2018 · Synced Sep 25, 2026, 1:35 PM EDT
Completed Not applicable Interventional Results available

Healthy Lifestyles for Mentally Ill People Who Have Experienced Weight Gain From Their Antipsychotic Medications - 2

NCT01052714
View directory record Official record
Conditions
Diabetes, Obesity, Weight Gain
Interventions
Lifestyle Balance
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
3
States / cities
Long Beach, California • Sepulveda, California • West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Sep 25, 2026, 1:35 PM EDT