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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Blast Traumatic Brain Injury Clear all
Not listed No phase listed Observational

Advanced MRI in Blast-related TBI

NCT00785304
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Interactive Metronome Technology for Blast-Related Traumatic Brain Injury"

NCT01248390
View directory record Official record
Conditions
Traumatic Brain Injury, Post-Concussion Syndrome
Interventions
Interactive metronome
Behavioral
Lead sponsor
The Defense and Veterans Brain Injury Center
Federal
Eligibility
18 Years to 55 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional

Combined Transcranial Magnetic Stimulation and Cognitive Treatment in Blast Traumatic Brain Injury

NCT01596569
View directory record Official record
Conditions
Traumatic Brain Injury, Cognitive Dysfunction, Blast Injury
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Intervention
Device · Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Sep 16, 2026, 7:47 AM EDT
Not listed No phase listed Observational

The Effects of Explosive Blast as Compared to Post-Traumatic Stress Disorder on Brain Function and Structure

NCT00631436
View directory record Official record
Conditions
Blast Injuries, Traumatic Brain Injury, Post-Traumatic Stress Disorders
Interventions
Not listed
Lead sponsor
Center for Veterans Research and Education
Other
Eligibility
20 Years to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 20, 2011 · Synced Sep 16, 2026, 7:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Military Service and Family Members for Post Concussive and Posttraumatic Stress Symptoms

NCT03191357
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
n/a observational
Other
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years and older
Enrollment
424 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blast Exposed Veterans With Auditory Complaints

NCT02122458
View directory record Official record
Conditions
Hearing Impairment, Hearing Aid Fitting
Interventions
mild-gain hearing aids with high-frequency emphasis over 6-months
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 50 Years
Enrollment
363 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
3
States / cities
Portland, Oregon • Pittsburgh, Pennsylvania • Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 16, 2026, 7:47 AM EDT
Recruiting No phase listed Observational

Cognitive and Vascular Functioning Following TBI

NCT06034509
View directory record Official record
Conditions
Traumatic Brain Injury, Cognitive Decline, Vascular Dementia
Interventions
No intervention. This is an observational study.
Other
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 74 Years
Enrollment
300 participants
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 16, 2026, 7:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Pilot Study to Identify Biomarkers Associated With Chronic Traumatic Brain Injury

NCT01171131
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Blood/saliva sampling
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 16, 2026, 7:47 AM EDT
Completed No phase listed Observational

Brain Indices of Risk for Posttraumatic Stress Disorder (PTSD) After Mild Traumatic Brain Injury (mTBI)

NCT01625962
View directory record Official record
Conditions
PTSD
Interventions
Not listed
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 50 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Sep 16, 2026, 7:47 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Imaging [18F]PI-2620 and [18F]Florbetaben in Military Service Members With Blast Related Mild Traumatic Brain Injury

NCT05337774
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
[18F]PI-2620
Drug
Lead sponsor
Lantheus Biosciences Ltd.
Industry
Eligibility
25 Years to 54 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional

Symptom-Targeted Approach to Rehabilitation for Concussion

NCT05091970
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Manualized cognitive rehabilitation for mild traumatic brain injury (mTBI)
Procedure
Lead sponsor
South Texas Veterans Health Care System
Federal
Eligibility
18 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Sep 16, 2026, 7:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI)

NCT01021137
View directory record Official record
Conditions
Dizziness, Brain Injury
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Mountain Home, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 4, 2019 · Synced Sep 16, 2026, 7:47 AM EDT
Completed No phase listed Observational

The Effects of Chronic Exposure to Low-Level Blasts

NCT01524822
View directory record Official record
Conditions
Tramatic Brain Injury
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional

Detection and Amelioration of Gamma Oscillation Abnormalities in Blast-Related Brain Injury

NCT03836976
View directory record Official record
Conditions
mTBI
Interventions
Auditory gamma sensory stimulation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Phase 2 Interventional

Hyperbaric Oxygen Therapy (HBO2T) for Post-Concussive Symptoms (PSC) After Mild Traumatic Brain Injury (mTBI)

NCT01220713
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post-Concussive Syndrome
Interventions
Hyperbaric Oxygen Therapy
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
19 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
Portsmouth, Virginia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 26, 2013 · Synced Sep 16, 2026, 7:47 AM EDT
Recruiting Phase 2 Interventional

Precision Biomarkers to Detect Brain Injury in Active-Duty United States Special Operations Forces With Repeated Blast Exposure

NCT07131475
View directory record Official record
Conditions
Blast Injury
Interventions
PBR28 TSPO PET
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional

LED Treatment to Improve Cognition and Promote Recovery in TBI

NCT02404402
View directory record Official record
Conditions
Traumatic Brain Injury, Posttraumatic Stress Disorder
Interventions
LED, sham LED
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Central Auditory Processing Disorders Associated With Blast Exposure

NCT00554801
View directory record Official record
Conditions
Central Auditory Processing Disorder, Traumatic Brain Injury, Hearing Loss
Interventions
Audiological testing
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional

Cognitive Rehabilitation of Blast Traumatic Brain Injury (TBI)

NCT01138020
View directory record Official record
Conditions
Traumatic Brain Injury, Cognitive Symptoms
Interventions
Cognitive Intervention, Educational intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 50 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 16, 2026, 7:47 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Tissue Repository and Master Database for Concussion Biomarker and Risk Calculator Development

NCT02519998
View directory record Official record
Conditions
Brain Concussion
Interventions
Concussion
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
10 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Sep 16, 2026, 7:47 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Blast Overpressure Longitudinal Study

NCT07606651
View directory record Official record
Conditions
Low-level Blast Exposure
Interventions
Not listed
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 50 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
3
States / cities
Bethesda, Maryland • Fort Bragg, North Carolina • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Use of the VOMS Tool With Military Personnel to Track mTBI Recovery and RTD Status

NCT02634944
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Vestibular Ocular Motor Screening Tool (VOMS)
Diagnostic Test
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 40 Years
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fort Lewis, Washington
Source: ClinicalTrials.gov public record
Updated Apr 5, 2020 · Synced Sep 16, 2026, 7:47 AM EDT
Completed Not applicable Interventional Results available

Brain Training to Enhance Frontal Lobe Reasoning

NCT01552473
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Brain Training Program 1, Brain Training Program 2
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
19 Years to 65 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 16, 2026, 7:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Central Auditory Processing Deficits Associated With Blast Exposure

NCT01567020
View directory record Official record
Conditions
Blast Injuries, Brain Injuries, Age Factors
Interventions
Diagnostic
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Sep 16, 2026, 7:47 AM EDT