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ClinicalTrials.gov public records Last synced Sep 18, 2026, 7:31 AM EDT

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Showing 1–24 of 79 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Blood Flow Restriction (BFR) Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Autoregulated and Non-autoregulated Blood Flow Restrictive Exercise on Indices of Arterial Stiffness

NCT05719090
View directory record Official record
Conditions
Arterial Stiffness, Healthy Lifestyle
Interventions
Delfi Personal Tourniquet Systems
Device
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 18, 2026, 7:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Can Blood Flow Restriction Therapy Improve Strength and Cross-Sectional Area for Shoulder External Rotators Better Than Exercise Alone?

NCT04596020
View directory record Official record
Conditions
Can Blood Flow Restriction Therapy Augments Strength Gains in the Rotator Cuff, Muscle Weakness
Interventions
Blood Flow Restriction Group (exercise with blood flow restriction using a Delfi unit)
Other
Lead sponsor
George Fox University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Newberg, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Sep 18, 2026, 7:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training as a Targeted Intervention for Rowers With Back Pain.

NCT07130812
View directory record Official record
Conditions
Low Back Pain
Interventions
blood flow restriction, Heavy load resistance training
Other
Lead sponsor
Loma Linda University
Other
Eligibility
13 Years to 20 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 18, 2026, 7:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blood Flow Restriction Training for The Shoulder

NCT04540367
View directory record Official record
Conditions
Healthy
Interventions
Blood flow restriction therapy
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 18, 2026, 7:31 AM EDT
Active, not recruiting Not applicable Interventional

Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair

NCT07498166
View directory record Official record
Conditions
Achilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow Restriction
Interventions
Blood Flow Restriction Resistance Training (BFR-RT), Sham Blood Flow Restriction, Standard Physical Therapy
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 18, 2026, 7:31 AM EDT
Terminated Not applicable Interventional

Blood Flow Restriction Concussion

NCT03695042
View directory record Official record
Conditions
Concussion Post Syndrome
Interventions
Blood Flow Restriction Training with Exercise
Other
Lead sponsor
Duke University
Other
Eligibility
14 Years to 30 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 18, 2026, 7:31 AM EDT
Withdrawn Not applicable Interventional

BFR After Biceps Tendon Repair and MPFLR

NCT05375071
View directory record Official record
Conditions
Patellofemoral Joint Dislocation, Bicep Tendon Rupture
Interventions
Blood Flow Restriction (BFR) Therapy, Physical Therapy
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 18, 2026, 7:31 AM EDT
Completed Not applicable Interventional

Low-Load Blood Flow Restriction on Patients With Multiple Sclerosis

NCT05177952
View directory record Official record
Conditions
Training Study, Multiple Sclerosis, Blood Flow Restriction
Interventions
Blood Flow Restriction, Standard of Care
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Sep 18, 2026, 7:31 AM EDT
Enrolling by invitation No phase listed Observational

Blood Flow Restriction Following ACLR w/Quad Autograft

NCT06636045
View directory record Official record
Conditions
Autografts, Blood Flow Restriction Therapy, Rehabilitation Outcome, Quadriceps Muscle Strength, Anterior Cruciate Ligament Reconstruction
Interventions
Not applicable- observational study
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
14 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 18, 2026, 7:31 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

BFR Therapy in Patients With Rotator Cuff Tears

NCT04384120
View directory record Official record
Conditions
Blood Flow Restriction
Interventions
Blood Flow Restriction Therapy, Traditional Therapy
Device · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 18, 2026, 7:31 AM EDT
Recruiting Not applicable Interventional

The Impact of Blood Flow Restriction Training in Adolescents After ACL Reconstruction: A Randomized Controlled Trial

NCT05754632
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Knee Injuries, Quadriceps Muscle Atrophy
Interventions
Blood Flow Restriction using Delfi Personalized Tourniquet System
Device
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 18, 2026, 7:31 AM EDT
Completed Not applicable Interventional

Low-load Resistance Training With Blood Flow Restriction in People With Parkinson's Disease

NCT05806775
View directory record Official record
Conditions
Parkinson Disease
Interventions
Low-load resistance training with blood flow restriction
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Sep 18, 2026, 7:31 AM EDT
Withdrawn Not applicable Interventional

Exercise Induced Hypoalgesia Diabetes

NCT05296642
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain
Interventions
Moderate Cycling, Personalized Tourniquet System
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Sep 18, 2026, 7:31 AM EDT
Active, not recruiting Not applicable Interventional

ORIF Distal Radius Blood Flow Restriction Therapy

NCT06136286
View directory record Official record
Conditions
Distal Radius Fractures
Interventions
Blood Flow Restriction (BFR) Cuff
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 18, 2026, 7:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Can Blood Flow Restriction Therapy Improve Strength for Shoulder External Rotators Better Than Exercise Alone

NCT03815760
View directory record Official record
Conditions
Muscular Weakness
Interventions
Blood Flow Restriction
Device
Lead sponsor
George Fox University
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Newberg, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Sep 18, 2026, 7:31 AM EDT
Completed Not applicable Interventional Results available

Blood Flow Restriction Following ACL Reconstruction

NCT03758755
View directory record Official record
Conditions
Anterior Cruciate Ligament Rupture
Interventions
Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
Device · Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
13 Years to 50 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Sep 18, 2026, 7:31 AM EDT
Completed Not applicable Interventional

Blood Flow Restriction Exercise Study

NCT02868021
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Strength testing, Short Physical Performance Battery (SPPB), Six-minute walk (SMW), Numerical pain scale, Self-assessed function, Muscle biopsies, Determination of 1 Repetition Maximum (1-RM), Blood flow restriction exercise, Borg CR10 scale
Device · Behavioral · Procedure
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Sep 18, 2026, 7:31 AM EDT
Active, not recruiting Not applicable Interventional

Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation

NCT05735236
View directory record Official record
Conditions
ACL Tear
Interventions
BFR Cuff
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
16 Years to 60 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Centennial, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 18, 2026, 7:31 AM EDT
Withdrawn Not applicable Interventional

Blood Flow Restriction Training Following Glenoid Labral Repair

NCT03675620
View directory record Official record
Conditions
Glenoid Labrum Tear
Interventions
BFR, Standard Rehabilitation
Device · Other
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Sep 18, 2026, 7:31 AM EDT
Recruiting Not applicable Interventional

Blood Flow Restriction Therapy in Achilles Injury

NCT04104126
View directory record Official record
Conditions
Achilles Injuries Tendon
Interventions
Standard of Care Physical Therapy, Blood flow restriction
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 18, 2026, 7:31 AM EDT
Terminated Not applicable Interventional

ACL Bone Health and Loading Study

NCT04682392
View directory record Official record
Conditions
ACL Tear
Interventions
Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab
Device · Other
Lead sponsor
Candice Dunkin, MS, LAT, ATC
Other
Eligibility
16 Years to 22 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 18, 2026, 7:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction and Creatine Supplementation in Women

NCT05877417
View directory record Official record
Conditions
Physical Inactivity
Interventions
Creatine Monohydrate, Blood Flow Restriction, Exercise
Dietary Supplement · Device · Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Sep 18, 2026, 7:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Influences of Single Chamber vs. Multi-chamber Blood Flow Restriction Cuffs

NCT06276673
View directory record Official record
Conditions
Blood Vessel Disease, Muscle Edema
Interventions
Delfi
Device
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Sep 18, 2026, 7:31 AM EDT
Withdrawn Not applicable Interventional

BFR Therapy After ACL Reconstruction

NCT03794570
View directory record Official record
Conditions
ACL Injury, Quadriceps Muscle Atrophy
Interventions
Blood flow restriction therapy - with Delfi Personalized Tourniquet System, Sham blood flow restriction therapy - with Delfi Personalized Tourniquet System
Device
Lead sponsor
Steadman Philippon Research Institute
Other
Eligibility
14 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Vail, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Sep 18, 2026, 7:31 AM EDT