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ClinicalTrials.gov public records Last synced Sep 25, 2026, 12:54 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Ankle Reconstruction, Blood Flow Restriction Therapy, Physical Therapy
Interventions
blood flow restriction
Device
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
5
States / cities
Lubbock, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training on Upper Extremity Grip Strength

NCT06535373
Conditions
Healthy Volunteers
Interventions
Blood flow restriction
Other
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pomona, California
Terminated Not applicable Interventional Results available

Blood Flow Restriction After Meniscus Repair

NCT04436523
Conditions
Meniscus Disorder, Meniscus, Torn Tibial, Meniscus Lesion, Meniscus Tear, Tibial, Atrophy, Muscular
Interventions
Blood flow restriction (Delfi Personalized Tourniquet System), Standard rehabilitation
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
San Francisco, California
Conditions
Blood Flow Restriction Training, Betaine Supplementation
Interventions
Betaine, Placebo
Dietary Supplement · Other
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Waco, Texas
Conditions
Low Back Pain
Interventions
blood flow restriction, Heavy load resistance training
Other
Lead sponsor
Loma Linda University
Other
Eligibility
13 Years to 20 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Completed Not applicable Interventional Accepts healthy volunteers

Lower Extremity BFR-randomized Controlled Trial Healthy Volunteers

NCT05868304
Conditions
Healthy
Interventions
BFR, Stanard strengthening program.
Device · Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Subjects With Severe, Refractory Sclerotic Skin Changes
Interventions
CO2 Laser, Ultrasound, Skin Biopsy
Device · Radiation · Diagnostic Test
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Muscular Weakness
Interventions
Blood Flow Restriction
Device
Lead sponsor
George Fox University
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Newberg, Oregon
Conditions
Low Back Pain, Knee Osteoarthritis
Interventions
Ischemic Preconditioning, Sham Intervention
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Parkinson Disease
Interventions
Low-load resistance training with blood flow restriction
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Spinal Cord Injury
Interventions
Blood Flow Restriction exercise, Traditional resistance exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
ACL Tear
Interventions
NMES and BFR, Standard physical therapy
Other
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Sunnyvale, California
Conditions
Arterial Stiffness, Healthy Lifestyle
Interventions
Delfi Personal Tourniquet Systems
Device
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Salisbury, Maryland
Conditions
Closed Femur Fracture
Interventions
Blood Flow Restriction, Delfi PTSII Tourniquet System
Other · Device
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 55 Years
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
8
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Bethesda, Maryland + 5 more
Conditions
Anterior Cruciate Ligament Injury
Interventions
DELFI PTS Personalized Tourniquet System for Blood Flow Restriction Training, Eccentric Exercise with BLAST Leg Press System, Concentric Exercise with BLAST Leg Press System
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 30 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Personalized Blood Flow Restriction for Anterior Cruciate Ligament Rehabilitation

NCT04635579
Conditions
Anterior Cruciate Ligament Tear
Interventions
Blood flow restriction
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
AirBand, uninflated AirBand
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Milford, Connecticut • North Haven, Connecticut
Recruiting Not applicable Interventional Accepts healthy volunteers

BFRT in Adolescents After ACL Reconstruction

NCT04390035
Conditions
Anterior Cruciate Ligament Rupture
Interventions
Blood Flow Restriction using Delfi Personalized Tourniquet System
Device
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
12 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure, Muscle Morphology, Perceptions
Interventions
Delfi Training Device
Device
Lead sponsor
Teri Herberger
Other
Eligibility
18 Years to 40 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Salisbury, Maryland
Conditions
Achilles Tendon Rupture, Achilles Tendon Surgery
Interventions
Blood flow restriction augmented physical therapy, Physical therapy
Device · Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Stroke
Interventions
Real Ischemic Conditioning, Sham Ischemic Conditioning
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Knee Injuries, Anterior Cruciate Ligament Injuries
Interventions
Blood Flow Restriction Therapy, Standard Postoperative Physical Therapy
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Redwood City, California
Conditions
Genetics in Hypertension
Interventions
low sodium diet, high sodium diet, renal plasma flow, SIEA collection
Other · Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Exercise in Health and Chronic Obstructive Pulmonary Disease

NCT02300064
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Knee-extensor exercise test, Exercise test with restricting/releasing blood flow, Exercise test with variable oxygen concentration and MRI, Exercise test with oral antioxidant or placebo cocktail
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah