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Showing 1–24 of 73 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Blood flow restriction cuff Clear all
Active, not recruiting Not applicable Interventional

The Role of Blood Flow Restriction Therapy in Postoperative Elderly Patients With Hip Fracture

NCT04809714
View directory record Official record
Conditions
Hip Fractures, Muscle Atrophy
Interventions
Blood Flow Restriction with Delfi Tourniquet System Cuff, Routine Post-operative Physical Therapy
Device · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 6, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss

NCT05929508
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Ischemic Preconditioning
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Sep 6, 2026, 9:14 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

BFR Therapy in Patients With Rotator Cuff Tears

NCT04384120
View directory record Official record
Conditions
Blood Flow Restriction
Interventions
Blood Flow Restriction Therapy, Traditional Therapy
Device · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional

The Effect of Ischemic Conditioning on Strength and Ambulation in Subjects with PAD

NCT04937179
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Disease, Amputation, Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
Interventions
Ischemic Conditioning Low - Sham Comparator, Ischemic Conditioning High - Active Comparator
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Sep 6, 2026, 9:14 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Influences of Blood Flow Restriction on Leg Press

NCT07052227
View directory record Official record
Conditions
Delfi Cuff, Fitcuff, Placebo - Control
Interventions
Delfi blood flow restriction cuff, Fitcuffs, Control
Device · Other
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Resistance Training Intervention on Vascular Function

NCT05451641
View directory record Official record
Conditions
Endothelial Function
Interventions
Blood flow restriction resistance training
Behavioral
Lead sponsor
Hirofumi Tanaka
Other
Eligibility
18 Years to 40 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 6, 2026, 9:14 PM EDT
Suspended Not applicable Interventional

Blood Flow Restriction & Tennis Elbow Rehab

NCT05237869
View directory record Official record
Conditions
Lateral Epicondylitis
Interventions
Blood Flow Restriction Device, Standard Physical Therapy
Device · Other
Lead sponsor
Julie Nuelle
Other
Eligibility
18 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 6, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

Effect of BFR Rehab After Achilles Tendon Rupture

NCT06254794
View directory record Official record
Conditions
Achilles Tendon Rupture
Interventions
Blood flow restriction with Delfi Personalized Tourniquet System (PTS), Physical therapy
Device · Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 6, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

Blood Flow Restriction Training After Patellar INStability

NCT04554212
View directory record Official record
Conditions
Patellar Dislocation, Knee Injuries, Leg Injury, Wounds and Injuries
Interventions
Blood Flow Restriction Training, Sham Blood Flow Restriction Training
Device
Lead sponsor
Caitlin Conley
Other
Eligibility
14 Years to 40 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
4
States / cities
Lexington, Kentucky • Foxborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blood Flow Restriction Training for The Shoulder

NCT04540367
View directory record Official record
Conditions
Healthy
Interventions
Blood flow restriction therapy
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Blood Flow Restriction Therapy Following ACL Tear

NCT04374968
View directory record Official record
Conditions
Anterior Cruciate Ligament Tear, Knee Injuries, Sport Injury
Interventions
Blood flood restriction cuff
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
West Bloomfield, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Sep 6, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

BFRT for Subacromial Pain

NCT06873113
View directory record Official record
Conditions
Shoulder Pain
Interventions
Active BFRT, Sham BFRT, Strengthening Exercises with BFRT, Skilled Physical Therapy Care
Device · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Sep 6, 2026, 9:14 PM EDT
Withdrawn Not applicable Interventional

Exercise Induced Hypoalgesia Diabetes

NCT05296642
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain
Interventions
Moderate Cycling, Personalized Tourniquet System
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low Intensity Blood Flow Restriction Training Study

NCT03055260
View directory record Official record
Conditions
Muscle Mass
Interventions
Blood flow restriction cuff, Blood Flow restriction Cuff-Placebo
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 49 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Sep 6, 2026, 9:14 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Can Blood Flow Restriction Therapy Improve Strength for Shoulder External Rotators Better Than Exercise Alone

NCT03815760
View directory record Official record
Conditions
Muscular Weakness
Interventions
Blood Flow Restriction
Device
Lead sponsor
George Fox University
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Newberg, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Sports Supplements on Blood Flow

NCT04278053
View directory record Official record
Conditions
Determine the Effects of Nitrosigine and Citrulline-malate on Flow-mediated Dilation Among Young Adults
Interventions
inositol-stabilized arginine silicate
Dietary Supplement
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 29 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated May 23, 2022 · Synced Sep 6, 2026, 9:14 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Exploring Blood Flow Restriction as an Accessible Fitness Solution for Healthy Aging in Seniors

NCT07460609
View directory record Official record
Conditions
Healthy Ageing
Interventions
Blood Flow Restriction Training Exercise, Health Education
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional

Low-Intensity Blood Flow Restriction Training as a Pre-Operative Rehabilitative Modality to Improve Post-Operative Outcomes for ACL Reconstruction

NCT04302558
View directory record Official record
Conditions
ACL Injury
Interventions
Exercise Blood Flow Restriction training, SHAM Exercise Blood Flow Restriction training
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years to 40 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 2, 2023 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional

The Effect of Cross-Education on Shoulder Arthroscopy

NCT04470570
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Repair
Interventions
Cross-Education, Blood-Flow Restriction Training
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Activation With Acute Bouts of Blood Flow Restricted Resistance Exercise

NCT05586451
View directory record Official record
Conditions
Muscle, Acute Exercise
Interventions
Traditional High Load Resistance Exercise (HLRE), Low Load Resistance Exercise with Blood Flow Restriction (LLBFR), Moderate Load Resistance Exercise with Blood Flow Restriction (MLBFR)
Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 6, 2026, 9:14 PM EDT
Enrolling by invitation Not applicable Interventional

Effect of Blood Flow-restricted Exercise Frequency on Strength Recovery Following Incomplete SCI

NCT07678437
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Blood flow-restricted exercise
Behavioral
Lead sponsor
Quality Living, Inc.
Other
Eligibility
19 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction

NCT05012982
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
AirBand, uninflated AirBand
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Milford, Connecticut • North Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional

Blood Flow Restriction Exercise for Those With SCI

NCT04889092
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Blood Flow Restriction exercise, Traditional resistance exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 6, 2026, 9:14 PM EDT
Completed Not applicable Interventional Results available

The Back Exercises to Neutralize Disability Study

NCT02308189
View directory record Official record
Conditions
Low Back Pain
Interventions
Exercise with blood flow restriction, Exercise
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 6, 2026, 9:14 PM EDT