Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 29, 2026, 8:04 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Prehabilitation
Interventions
Prehabilitation Program
Combination Product
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 90 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Austin, Texas
Conditions
Peripheral Arterial Disease
Interventions
Blood Flow Restriction Cuff System, Low-load Resistance Training, High-load Resistance Training
Behavioral
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Knoxville, Tennessee
Conditions
Severe Muscle Atrophy, Muscle Weakness
Interventions
Blood flow restriction training
Other
Lead sponsor
Cincinnati Sportsmedicine Research and Education Foundation
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Interventions
Blood Flow Restriction Cuff, Sham and standard of Care Therapy
Device · Procedure
Lead sponsor
Gaylord Hospital, Inc
Other
Eligibility
15 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
6
States / cities
Cheshire, Connecticut • Cromwell, Connecticut • Farmington, Connecticut + 2 more
Completed Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Resistance Training Intervention on Vascular Function

NCT05451641
Conditions
Endothelial Function
Interventions
Blood flow restriction resistance training
Behavioral
Lead sponsor
Hirofumi Tanaka
Other
Eligibility
18 Years to 40 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Austin, Texas
Terminated Not applicable Interventional Results available

Blood Flow Restriction Training in ACL Surgery

NCT05245864
Conditions
Anterior Cruciate Ligament Injuries
Interventions
blood flow restriction, physical therapy standard of care
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 34 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree, Musculoskeletal Injury
Interventions
Blood Flow Restriction Therapy, Standard Physical Therapy
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Parkinson Disease
Interventions
Low-load resistance training with blood flow restriction
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Spinal Cord Injury Cervical
Interventions
Blood flow-restricted resistance exercise
Behavioral
Lead sponsor
Quality Living, Inc.
Other
Eligibility
19 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Training With Blood Flow Restriction

NCT05863039
Conditions
Healthy
Interventions
Blood flow restriction, Regular training type 1, Regular training type 2
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Norman, Oklahoma
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training for People With Disabilities

NCT06441422
Conditions
Weakness, Muscle
Interventions
Blood flow restriction training, No blood flow restriction training
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Knee Injuries
Interventions
Blood Flow Restriction, Standard rehabilitation
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 50 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
West Point, New York • Fort Bragg, North Carolina
Conditions
Bicep Tendon Rupture
Interventions
Blood Flow Restriction Therapy
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Completed Not applicable Interventional

Blood Flow Restriction Exercise Study

NCT02868021
Conditions
Osteoarthritis, Knee
Interventions
Strength testing, Short Physical Performance Battery (SPPB), Six-minute walk (SMW), Numerical pain scale, Self-assessed function, Muscle biopsies, Determination of 1 Repetition Maximum (1-RM), Blood flow restriction exercise, Borg CR10 scale
Device · Behavioral · Procedure
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Achilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow Restriction
Interventions
Blood Flow Restriction Resistance Training (BFR-RT), Sham Blood Flow Restriction, Standard Physical Therapy
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

The Back Exercises to Neutralize Disability Study

NCT02308189
Conditions
Low Back Pain
Interventions
Exercise with blood flow restriction, Exercise
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Athens, Ohio
Conditions
Anterior Shoulder Dislocation, Recurrent Shoulder Dislocation, Shoulder Subluxation, Surgery
Interventions
Blood flow restriction therapy, Standard Physical Thearapy
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
17 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
West Point, New York
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Exploring Blood Flow Restriction as an Accessible Fitness Solution for Healthy Aging in Seniors

NCT07460609
Conditions
Healthy Ageing
Interventions
Blood Flow Restriction Training Exercise, Health Education
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waco, Texas
Conditions
Knee Osteoarthritis, Symptomatic Knee Osteoarthritis
Interventions
partial blood flow restriction, Low intensity exercise without partial blood flow restriction
Other
Lead sponsor
University of Iowa
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Training Study, Multiple Sclerosis, Blood Flow Restriction
Interventions
Blood Flow Restriction, Standard of Care
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Aging
Interventions
Exercise
Other
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Spinal Cord Injury
Interventions
Blood Flow Restriction exercise, Traditional resistance exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Phase 1 Interventional Accepts healthy volunteers

Nutritional and Contractile Regulation of Muscle Growth

NCT00891696
Conditions
Sarcopenia
Interventions
Rapamycin, Amino acid supplementation, Low-intensity resistance exercise, Sodium nitroprusside, Blood flow restriction cuff
Drug · Other · Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 85 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Knee Osteoarthritis
Interventions
Blood Flow Restriction Training (BFRT)
Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
60 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Antonio, Texas