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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:05 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 423 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Botulinum toxin(Botox) Clear all

Conditions: Urinary Incontinence, Overactive Bladder
Interventions: Botulinum toxin type A, Placebo; Biological · Drug
Lead sponsor: Ipsen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 227 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 32
States / cities: Birmingham, Alabama • Tucson, Arizona • Long Beach, California + 27 more

Conditions: Overactive Bladder
Interventions: botulinum toxin Type A (200U), botulinum toxin Type A (300U), Normal Saline (Placebo); botulinum toxin Type A (200U), Normal Saline (Placebo); botulinum toxin Type A (300U); Biological · Other
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 416 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Spasmodic Dysphonia
Interventions: Zinc gluconate supplement, Botulinum toxin type A; Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 99 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Hyperhidrosis
Interventions: Vehicle, ANT-1207; Biological
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 19
States / cities: Hialeah, Florida • Miami, Florida • Pinellas Park, Florida + 16 more

Conditions: Cervicalgia, Low Back Pain
Interventions: Botulinum Toxins; Drug
Lead sponsor: VA Connecticut Healthcare System; Federal
Eligibility: 18 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Plantar Fasciitis
Interventions: Botulinum Toxin A, Dexamethasone; Drug
Lead sponsor: Western Institute for Veterans Research; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms
Interventions: onaBoNT-A + placebo, Tamsulosin + placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years and older · Male only
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Forehead Rhytides, Forehead Wrinkles
Interventions: Botulinum toxin type A, 2.5% lidocaine/2.5% prilocaine, petrolatum ointment; Drug · Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Hypertrophic Scar
Interventions: Botox; Drug
Lead sponsor: Roy G. Geronemus, M.D.; Other
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Forward Head Posture With Associated Episodic Headache Disorder
Interventions: Botox, Saline; Drug
Lead sponsor: The Research Center of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Oceanside, California

Conditions: Arthritis Multiple Joint
Interventions: Botulinum Toxin Type A, Steroid - Triamcinolone Acetonide, Lidocaine; Drug
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Post-stroke Spasticity, Spasticity Post-Traumatic Brain Injury
Interventions: Botulinum toxin type A; Biological
Lead sponsor: Ipsen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 352 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 15
States / cities: Scottsdale, Arizona • Downey, California • Oxnard, California + 12 more

Conditions: Episodic Migraine
Interventions: Botulinum toxin type A, Placebo; Biological · Other
Lead sponsor: Ipsen; Industry
Eligibility: 18 Years and older
Enrollment: 751 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 66
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 58 more

Conditions: Mixed Urinary Incontinence, Stress Urinary Incontinence, Urgency Incontinence
Interventions: OnabotulinumtoxinA (Botox ®) Injections, Saline Injections; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Masseter Muscle Prominence
Interventions: BOTOX, Placebo; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years and older
Enrollment: 207 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 20
States / cities: Los Angeles, California • Newport Beach, California • Vista, California + 14 more

Conditions: Migraine Disorders
Interventions: Botulinum Toxin Type A, Placebo (saline); Biological · Other
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 679 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Masseter Muscle Prominence
Interventions: OnabotulinumtoxinA, Normal saline; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 14
States / cities: Birmingham, Alabama • Los Angeles, California • San Diego, California + 10 more

Conditions: Cervical Dystonia
Interventions: Botulinum toxin type A; Biological
Lead sponsor: Ipsen; Industry
Eligibility: 18 Years and older
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 41
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Tucson, Arizona + 34 more

Conditions: Brow Ptosis
Interventions: Juvederm XC, Botox; Device · Drug
Lead sponsor: Skin Care and Laser Physicians of Beverly Hills; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Facial Wrinkles
Interventions: Xeomin to right side of face in half of the subjects; Xeomin to left side of face in the other half of subjects, Botox to right side of face in half of the subjects (randomized); Botox to the left side of the face in the other half of subjects; Drug
Lead sponsor: YMD Eye and Face; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Sarasota, Florida

Conditions: Facial Rhytides, Glabellar Rhytides
Interventions: OnabotulinumtoxinA, Normal Saline; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 787 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 10
States / cities: Little Rock, Arkansas • Los Angeles, California • Newport Beach, California + 6 more

Conditions: Cerebral Palsy
Interventions: Dysport Injectable Product; Drug
Lead sponsor: Columbia University; Other
Eligibility: 5 Years to 17 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Glabellar Frown Lines
Interventions: PrabotulinumtoxinA-Xvfs, OnabotulinumtoxinA; Drug
Lead sponsor: Evolus, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 154 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Boca Raton, Florida

Conditions: Wrinkles
Interventions: Onabotulinum Toxin A, Incobotulinum Toxin A; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 20 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

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Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 1

Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder

Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia

Clinical Trial To Evaluate ANT-1207 In Participants With Primary Axillary Hyperhidrosis

New Approaches in Evaluating Patients' Response to Botulinum Toxins in the Treatment of Chronic Neck Pain and Back Pain

The Efficacy of Botulinum Toxin vs. Corticosteroid for the Treatment of Refractory Plantar Fasciitis

Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS

Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment

Treatment of Hypertrophic Scars With Intradermal Botox

Safety and Efficacy Study of Botox in the Treatment of Forward Head Posture With Associated Episodic Headache Disorder

Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint

Dysport® Adult Lower Limb Spasticity Follow-on Study

A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Episodic Migraine in Adults

The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence

A Study to Assess BOTOX Injections for the Change of Masseter Muscle Prominence in Adult Participants

A Study Using Botulinum Toxin Type A as Headache Prophylaxis for Migraine Patients With Frequent Headaches

BOTOX® (onabotulinumtoxinA) Treatment of Masseter Muscle Prominence

Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia

Brow Enhancement Study

Split-Face Prospective Study Comparing Botox to Xeomin for the Treatment of Facial Wrinkles

A Safety and Efficacy Study of OnabotulinumtoxinA in Upper Facial Rhytides

Effect of Dysport Injections on Energy Expenditure and Walking Efficiency in Children With Cerebral Palsy

Study to Demonstrate Safety and Duration of Effect of 40 Units of PrabotulinumtoxinA-xvfs to Treat Glabellar Lines

A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles