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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:35 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 423 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Botulinum toxin(Botox) Clear all

Conditions: Raynaud's Disease
Interventions: onabotulinum toxin type-A; Drug
Lead sponsor: Southern Illinois University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Springfield, Illinois

Conditions: Hyperhidrosis
Interventions: Botulinum Toxin Type A; Biological
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 424 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Cleft Lip, Cleft Lip Scar
Interventions: Botulinum Toxin Type A (BOTOX) Injection, Normal Saline; Drug
Lead sponsor: Children's National Research Institute; Other
Eligibility: 0 Days to 12 Months
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Anxiety Disorder Social, Anxiety
Interventions: botulinum toxin A, Placebo; Drug · Other
Lead sponsor: Daniel Lieberman; Other
Eligibility: 18 Years to 65 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Post-operative Excessive Scarring
Interventions: Botulinum Toxin, Saline; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Frown Lines
Interventions: DaxibotulinumtoxinA for injection; Biological
Lead sponsor: Revance Therapeutics, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Boca Raton, Florida • Coral Gables, Florida

Conditions: Pediatrics, Muscle Spasticity, Cerebral Palsy, Stroke
Interventions: botulinum toxin Type A, Normal Saline (Placebo); Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 2 Years to 16 Years
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 20
States / cities: Pasadena, California • Pomona, California • Aurora, Colorado + 15 more

Conditions: Urinary Bladder, Overactive
Interventions: onabotulinumtoxinA; Biological
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 3
States / cities: Shreveport, Louisiana • Baltimore, Maryland • Richmond, Virginia

Conditions: Interstitial Cystitis, Bladder Pain Syndrome
Interventions: Transvaginal botulinum toxin A (BTA) injection; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Cervical Dystonia
Interventions: incobotulinumtoxinA (Xeomin) (240 Units), incobotulinumtoxinA (Xeomin) (120 Units), Placebo; Drug
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 233 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Patellofemoral Pain Syndrome
Interventions: Botulinum toxin A + exercise, Placebo; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Urinary Incontinence
Interventions: Botox, Placebo; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 21 Years to 90 Years · Female only
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2011
U.S. locations: 3
States / cities: Sacramento, California • Boston, Massachusetts • Durham, North Carolina

Conditions: Acne Vulgaris
Interventions: Botulinum Neurotoxin Type A, Bacteriostatic saline; Drug
Lead sponsor: DeNova Research; Other
Eligibility: 18 Years to 50 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Facial Rhytides, Crow's Feet Lines, Glabellar Lines, Nasolabial Fold
Interventions: onabotulinumtoxinA, bimatoprost ophthalmic solution 0.03%, JUVÉDERM® ULTRA XC, JUVÉDERM® ULTRA PLUS XC, JUVÉDERM® VOLUMA® XC; Biological · Drug · Device
Lead sponsor: Allergan; Industry
Eligibility: 35 Years to 65 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Skin Aging
Interventions: botulinum toxin Type A; Biological
Lead sponsor: Allergan; Industry
Eligibility: 35 Years to 55 Years · Female only
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 2
States / cities: West Palm Beach, Florida • Livonia, Michigan

Conditions: Parkinson's Disease, Neurogenic Bladder, Urinary Incontinence, Clostridium Botulinum Toxin Adverse Reaction
Interventions: Cystoscopic injection of Botox into the urinary bladder; Drug
Lead sponsor: Stanford University; Other
Eligibility: 50 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Stanford, California

Conditions: Contact Ulcer of Vocal Folds, Granuloma of Vocal Cords, Granuloma, Laryngeal, Granuloma
Interventions: onabotulinumtoxinA, omeprazole (proton pump inhibitor); Drug
Lead sponsor: Phillip Song, MD; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Scar, Hypertrophic Scar, Mammary Disorder
Interventions: Botulinum Toxins, Normal saline; Drug · Other
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Essential Tremor
Interventions: Botulinum toxin, Placebo; Drug · Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Carpal Tunnel Syndrome
Interventions: Botulinum toxin, Corticosteroid injection into Carpal Tunnel; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Plantar Fasciitis
Interventions: Botulinum Toxins, Type A, Placebo; Biological
Lead sponsor: Revance Therapeutics, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 5
States / cities: Duluth, Georgia • Des Plaines, Illinois • Overland Park, Kansas + 2 more

Conditions: Pain
Interventions: Botulinum Toxin Type A, Saline; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Stanford, California

Conditions: Glabellar Frown Lines
Interventions: Botulinum Toxins, Type A; Biological
Lead sponsor: Revance Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 2,691 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 56
States / cities: Birmingham, Alabama • Beverly Hills, California • Encinitas, California + 44 more

Conditions: Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis; Lumbar Region
Interventions: Botulinum toxin type A, Isometric Yoga-like exercise, Placebo; Drug · Behavioral
Lead sponsor: Manhattan Physical Medicine and Rehabilitation, LLP; Other
Eligibility: 14 Years to 18 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Manhattan, New York

Search by objective public record fields.

A Two-Part Study of BOTOX® Therapy for Ischemic Digits

A Study Using Botulinum Toxin Type A in Patients With Axillary Hyperhidrosis

Cleft Lip Scarring After Botox

A Study of the Efficacy of Botox in the Treatment of Social Anxiety Disorder

Botulinum Toxin is a Potential Prophylactic Therapy for Minimizing Post-excisional Scarring (Allergan Botox Scar Study)

Efficacy and Safety of DaxibotulinumtoxinA (DAXI) for Injection for Treatment of Forehead Lines (Frontalis)

BOTOX® Treatment in Pediatric Upper Limb Spasticity

Voiding Efficiency, a Predictor of Clean Intermittent Catheterization (CIC)

Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome

IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Cervical Dystonia

Botox for Non-surgical Lateral Release in Patellofemoral Pain

A Multi-Center Trial of Botox for Severe Urge Urinary Incontinence

Safety and Efficacy of the Use of Botox on Acne

Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study)

Patient Satisfaction With Treatment of BOTOX® Cosmetic for the Temporary Correction of Moderate to Severe Glabellar Lines

Safety and Efficacy of botulinumA Toxin (BotoxA) for Treatment of Neurogenic Bladder of Parkinson's Disease

Efficacy Study of Botulinum Toxin (BOTOX) Injections to Treat Vocal Fold Granulomas

The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation

Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET)

Botulinum Toxin for Carpal Tunnel Syndrome

Phase 2 DaxibotulinumtoxinA for Injection for the Management of Plantar Fasciitis

Subcutaneous Botulinum Toxin for Cutaneous Allodynia - Enriched Responder Trial

Safety of Single and Repeat Treatments of DaxibotulinumtoxinA for Injection for Treatment of Moderate to Severe Glabellar Lines

Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis