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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:02 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 385–408 of 423 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Botulinum toxin(Botox) Clear all

Conditions: Chronic Testicular Pain
Interventions: Botox Injection, Normal saline injection; Drug · Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: Male only
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Urinary Incontinence, Multiple Sclerosis, Neurogenic Bladder
Interventions: OnabotulinumtoxinA, Placebo (Normal Saline); Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Mountlake Terrace, Washington

Conditions: Neurogenic Bladder Dysfunction Nos, Spinal Cord Injury
Interventions: BOTOX-A, Saline injection; Drug · Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 50 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Lateral Canthal Lines, Crow's Feet
Interventions: ANT-1401, Vehicle; Biological
Lead sponsor: Anterios Inc.; Industry
Eligibility: 30 Years to 60 Years
Enrollment: 145 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 10
States / cities: Miami, Florida • Pinellas Park, Florida • West Palm Beach, Florida + 7 more

Conditions: Hyperhidrosis
Interventions: Botulinum Toxin Type A (Botox); Drug
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: Salt Lake City, Utah

Conditions: Unilateral Spastic Cerebral Palsy
Interventions: Botulinum toxin type A; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 5 Years to 18 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Spasticity Secondary to Either a Disorder or Trauma, Spinal Cord Injury (SCI), Brain Injury, Tumor, Stroke
Interventions: Botox, MYOBLOC; Drug
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Overactive Bladder
Interventions: onabotulinumtoxinA, normal saline; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 548 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Laguna Hills, California

Conditions: Blepharospasm of Both Eyelids, Blepharospasm of Left Eyelid, Blepharospasm of Right Eyelid, Blepharospasm, Benign Essential, Blepharospasm
Interventions: Botulinum Neurotoxin Type A; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Urinary Incontinence
Interventions: OnabotulinumtoxinA; Biological
Lead sponsor: Allergan; Industry
Eligibility: 5 Years to 17 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 14
States / cities: Birmingham, Alabama • Los Angeles, California • Orange, California + 11 more

Conditions: Moderate to Severe Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines, and Lateral Canthal Lines)
Interventions: NT 201, Placebo; Drug
Lead sponsor: Merz North America, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 362 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 12
States / cities: Encino, California • Newport Beach, California • San Diego, California + 7 more

Conditions: Essential Tremor
Interventions: RenuGel, Botulinum Toxin; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Spinal Cord Injury, Pain
Interventions: botulinum toxin A, placebo; Drug · Other
Lead sponsor: Craig Hospital; Other
Eligibility: 15 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Englewood, Colorado

Conditions: Wrinkles, Photoaging, Fine Lines
Interventions: Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer, Sunscreen; Procedure · Combination Product
Lead sponsor: Revision Skincare; Industry
Eligibility: 35 Years to 60 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 3
States / cities: Fort Lauderdale, Florida • Coralville, Iowa • Columbus, Ohio

Conditions: Skin Aging
Interventions: Placebo, Botulinum Toxin Type A; Drug
Lead sponsor: Revance Therapeutics, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Pain From onabotulinumtoxinA Injections
Interventions: onabotulinumtoxinA prophylaxis with Lidocaine, OnabotulinumtoxinA prophylaxis with Saline; Procedure
Lead sponsor: Association of Migraine Disorders; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: East Providence, Rhode Island

Conditions: Skin Cancer Excision Site, Basal Cell Carcinoma, Squamous Cell Carcinoma, Melanoma
Interventions: Abobotulinumtoxin-A, Control- Saline injection; Drug · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Arthritis, Shoulder Pain
Interventions: intra-articular botulinum toxin type a; Drug
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Cerebral Palsy, Muscle Spasticity, Children
Interventions: Botulinum toxin type A, Placebo; Biological · Drug
Lead sponsor: Ipsen; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 241 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 8
States / cities: Aurora, Colorado • Chicago, Illinois • New Orleans, Louisiana + 5 more

Conditions: Scleroderma
Interventions: Botulinum toxin(Botox); Biological
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Gingival Exposure
Interventions: Botulinum toxin type A; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Migraine Headache
Interventions: Botulinum Toxin Type A; Drug
Lead sponsor: HealthPartners Institute; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Glabellar Frown Lines
Interventions: Botulinum toxin, Type A, 0.9% sterile, unpreserved saline; Biological · Other
Lead sponsor: Evolus, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 324 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Beverly Hills, California

Conditions: Drooling
Interventions: Botulinum Toxin Type B (Myobloc), Matched placebo to Myobloc; Biological
Lead sponsor: Solstice Neurosciences, LLC, a subsidiary of US WorldMeds, LLC; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 18
States / cities: Scottsdale, Arizona • Northridge, California • Oxnard, California + 15 more

Search by objective public record fields.

Botulinum Toxin for the Management of Chronic Orchialgia

Safety and Efficacy Study of OnabotulinumtoxinA for the Treatment of Urinary Incontinence Due to Neurogenic Detrusor Overactivity (NDO) in Non-Catheterizing Patients With Multiple Sclerosis (MS)

Botox-A Injection to Improve Bladder Function in Early Spinal Cord Injury (#H-20344)

Dose Finding Study In Subjects With Crow's Feet

Hyperhidrosis in Patients With Amputations-Botox

Muscle Elastography in Spastic Cerebral Palsy

Myobloc Atrophy Study

Botulinum Toxin Type A for the Treatment of Patients With Idiopathic Overactive Bladder With Urinary Incontinence

DaxibotulinumtoxinA for Blepharospasm

Study of OnabotulinumtoxinA (BOTOX®) for Urinary Incontinence Due to Neurogenic Detrusor Overactivity in Pediatric Patients

Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Lateral Canthal Lines) in Subjects With Moderate to Severe Upper Facial Lines

Essential Voice Tremor: A Study of Botulinum Toxin Treatment and Injection Augmentation

Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.

Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines

Efficacy and Safety of Botulinum Toxin Type A for Moderate to Severe Crow's Feet Lines

Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Injections for Chronic Migraine

Impact of Dysport on PMFF Donor Scar

Intra-Articular Injection of Botulinum Toxin Type A for Shoulder Pain

Dysport® Pediatric Lower Limb Spasticity Study

The Effects of Botulinum Toxin on Oral Aperture in Patients With Scleroderma

Botox for Gummy Smile

Pilot Study of BOTOX for Migraine Headaches

A Phase III Study to Demonstrate the Safety and Efficacy of DWP-450 to Treat Glabellar Lines - EV-002

A Multi-Center Study of MYOBLOC for the Treatment of Sialorrhea in Parkinson's Disease Patients