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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:36 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 423 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Botulinum toxin(Botox) Clear all

Conditions: Platysma Prominence
Interventions: OnabotulinumtoxinA, Placebo; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years and older
Enrollment: 408 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 26
States / cities: Glendale, Arizona • Scottsdale, Arizona • Encino, California + 23 more

Conditions: Cerebral Palsy, Muscle Spasticity
Interventions: Low-magnitude vibration, Botox; Device · Drug
Lead sponsor: University of Delaware; Other
Eligibility: 2 Years to 12 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Newark, Delaware • Wilmington, Delaware

Conditions: Compartment Syndrome of Leg
Interventions: OnabotulinumtoxinA Injection; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Axillary Hyperhidrosis
Interventions: Botulinum Toxin Type A, Suction-Curettage; Drug · Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Glabellar Frown Lines
Interventions: QM1114-DP, Placebo; Biological
Lead sponsor: Galderma R&D; Industry
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 9
States / cities: Homewood, Alabama • Manhattan Beach, California • Vista, California + 6 more

Conditions: Spasticity
Interventions: Botulinum Toxin Type A, Intrathecal baclofen administered by the Medtronic SyncroMed(TM) pump (ITB); Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Lateral Canthal Lines, Crow's Feet, Facial Wrinkles
Interventions: Botulinum Toxin Type A, Placebo (Dose B); Drug
Lead sponsor: Revance Therapeutics, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Overactive Bladder (OAB)
Interventions: OnabotulinumtoxinA (BoNTA), Percutaneous tibial nerve stimulation (PTNS); Biological · Procedure
Lead sponsor: Medstar Health Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • New York, New York

Conditions: Chronic Migraine, Headaches
Interventions: onabotulinumtoxinA; Biological
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Encinitas, California

Conditions: Masticatory Myofascial Pain Syndrome
Interventions: Onabotulinumtoxin A, Placebo; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: New York, New York

Conditions: Frown Lines
Interventions: Botulinum toxin A "BoNT/A-DP", Botulinum toxin A "Botox Cosmetics"; Biological
Lead sponsor: Croma-Pharma GmbH; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Santa Monica, California • Coral Gables, Florida

Conditions: Overactive Bladder, Urinary Incontinence
Interventions: botulinum toxin Type A, Placebo; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 313 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Gastroparesis
Interventions: Botulinum toxin A, Placebo; Drug
Lead sponsor: Temple University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Osteoarthritis, Knee
Interventions: Botulinum toxin type A (Btx-A), Cortisone; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 40 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Muscle Spasticity
Interventions: onabotulinumtoxinA; Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 744 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 26
States / cities: Loma Linda, California • Newport Beach, California • Sacramento, California + 23 more

Conditions: Trigeminal Neuralgia
Interventions: OnabotulinumtoxinA 100 UNT [Botox], Sodium Chloride 0.9% for Injection, Preservative Free; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Stanford, California

Conditions: Glabellar Frown Lines
Interventions: Botulinum toxin, Type A, 0.9% sterile, unpreserved saline; Biological · Other
Lead sponsor: Evolus, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Boca Raton, Florida

Conditions: Lateral Canthal Lines, Crow's Feet, Facial Wrinkles
Interventions: Botulinum Toxin Type A, Placebo; Drug
Lead sponsor: Revance Therapeutics, Inc.; Industry
Eligibility: 30 Years to 60 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Glabellar Frown Lines
Interventions: Botulinum Toxins, Type A, Placebos; Biological
Lead sponsor: Revance Therapeutics, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 303 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 15
States / cities: Birmingham, Alabama • Beverly Hills, California • Newport Beach, California + 11 more

Conditions: New Daily Persistent Headache
Interventions: OnabotulinumtoxinA; Drug
Lead sponsor: St. Luke's-Roosevelt Hospital Center; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Psoriasis Vulgaris
Interventions: injection of botulinum toxin type A.; Biological
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Empty Nose Syndrome, Atrophic Rhinitis
Interventions: Botulinum Toxin Type A; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Overactive Bladder
Interventions: botulinum toxin Type A, Normal Saline (Placebo); Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Post-stroke Spasticity of the Upper Limb
Interventions: IncobotulinumtoxinA (400 Units), Placebo Comparator; Drug
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 317 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 13
States / cities: Downey, California • Fountain Valley, California • Miami, Florida + 10 more

Search by objective public record fields.

A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Moderate to Severe Platysma Prominence

Effect of Botox and Vibration on Bone in Children With Cerebral Palsy

Botox for the Treatment of Chronic Exertional Compartment Syndrome

Botox and Suction-Curettage for Treatment of Excessive Underarm Sweating (Axillary Hyperhidrosis)

Assess Aesthetic Improvement and Onset of QM1114-DP in Subjects With Moderate to Severe Glabellar Lines

Vanderbilt University Spasticity Management Program Evaluation Plan

Efficacy and Safety Study of RT001 for the Treatment of Moderate to Severe Lateral Canthal Lines in Adults

PTNS vs Botox of Refractory OAB

A Retrospective Study to Evaluate the Effectiveness and Benefit of onabotulinumtoxinA in Patients With Chronic Migraines

MRI Study of OnabotulinumtoxinA (OnabotA) Effect on Jaw Muscle Pain

Study to Compare 2 Botulinum Type A Toxins in the Treatment of Glabellar Frown Lines

A Research Study for Patients With Overactive Bladder

Placebo Controlled Trial of Botulinum Toxin for Gastroparesis

Is Botox Effective in Relieving Pain From Knee Osteoarthritis?

An Adult Spasticity Registry of OnabotulinumtoxinA Treatment

OnabotulinumtoxinA for Trigeminal Neuralgia

A Phase III Study to Demonstrate the Safety and Efficacy of DWP-450 to Treat Glabellar Lines - EV001

Efficacy and Safety Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines

Efficacy and Safety of DaxibotulinumtoxinA for Injection to Treat Moderate to Severe Glabellar Lines

OnabotulinumtoxinA for the Treatment of New Daily Persistent Headache: an Open Label Study

Use of Botulinum Toxin to Treat Psoriasis

Benefits of the Use of Botox in the Treatment of Empty Nose Syndrome Syndrome

Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Arm After a Stroke