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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:10 AM EDT

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Showing 337–360 of 843 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Brain Training Clear all
Recruiting Not applicable Interventional

Auditory Plasticity Training

NCT06628505
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Speech in Noise Training, Spatial Hearing Training Group, Spatial Hearing Control Group
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 55 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 23, 2026, 8:10 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effect of Exercise Training on Physical, Cognitive, and Behavioral Function in People With TBI

NCT02504866
View directory record Official record
Conditions
Traumatic Brain Injury (TBI)
Interventions
Vigorous exercise, Light to moderate exercise
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 79 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional Results available

Combining Attention and Metacognitive Training to Improve Goal Directed Behavior in Veterans With TBI

NCT04044456
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Goal Management Training, Attention Training, Brain Health Workshop, National geographic movies
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 30, 2024 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional

Cognitive Rehabilitation:ACTION Training for Soldiers With Executive Dysfunction

NCT02352441
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Implementation Intentions(II)
Other
Lead sponsor
Allina Health System
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Oct 23, 2026, 8:10 AM EDT
Not listed Not applicable Interventional

Improving Balance in TBI Using Virtual Reality

NCT02298231
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Standard of Care Balance Intervention, Mystic Isle Balance Intervention, Mystic Isle Balance Intervention with Dual Task
Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 14, 2016 · Synced Oct 23, 2026, 8:10 AM EDT
Recruiting Phase 2Phase 3 Interventional

Exercise and Intranasal Insulin in Type 2 Diabetes

NCT07675499
View directory record Official record
Conditions
Type 2 Diabetes, Insulin Sensitivity/Resistance, Cognition, Brain Blood Flow
Interventions
Intranasal Insulin, Intranasal Placebo, High Intensity Exercise
Drug · Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
55 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
4
States / cities
New Brunswick, New Jersey • Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 23, 2026, 8:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment

NCT07225400
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
Spatial Navigation training
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Manhattan, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional

Computerized Memory Enhancing Treatment in MCI

NCT05332522
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Neuroplasticity-based Computerized Cognitive Remediation
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
55 Years to 85 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 23, 2026, 8:10 AM EDT
Recruiting Not applicable Interventional

Personalized Cognitive Integrated Motor Training Using Virtual Reality to Improve Gait and Balance

NCT06473987
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Personalized cognitive-sensorimotor VR/AR training, Traditional dual-task training, Standard of Care
Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 23, 2026, 8:10 AM EDT
Recruiting Not applicable Interventional

Breast Cancer, Reasoning, and Activity Intervention

NCT04816006
View directory record Official record
Conditions
Breast Cancer, Breast Neoplasms, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Cancer-related Cognitive Dysfunction
Interventions
Aerobic Exercise Training, Health Education (Active comparator)
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Phase 1 Interventional

Computerized Attention Training for Individuals With Acquired Brain Injury

NCT01641432
View directory record Official record
Conditions
Acquired Brain Injury, Stroke, Hemispatial Neglect
Interventions
Tonic and Phasic Attention Training, Active Comparator
Behavioral
Lead sponsor
Posit Science Corporation
Industry
Eligibility
21 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2014 · Synced Oct 23, 2026, 8:10 AM EDT
Recruiting Phase 1Phase 2 Interventional

A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis

NCT03952637
View directory record Official record
Conditions
Lysosomal Diseases, Gangliosidosis, GM1
Interventions
AAV9-GLB1, Abdominal ultrasound, Rituximab, Sirolimus, Methylprednisolone, Prednisone, Audiology assessment with ABR, Bone density scan (DEXA), Electrocardiogram (EKG), Echocardiogram, Electroencephalogram (EEG) awake and extended overnight, Laboratory tests, Lumbar puncture, Brain MRI/MRS/fMRI, Neurocognitive testing, Neurology exam, PICC or other Central line placement, Skeletal survey, Skin biopsy, Speech and modified barium swallow study, Ophthalmology exam
Biological · Procedure · Drug + 3 more
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
6 Months to 12 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Changes With Game Training in Aging

NCT02490137
View directory record Official record
Conditions
Aging, Dementia
Interventions
Race Car Video Game
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Oct 23, 2026, 8:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Brain Imaging Study of Tai Chi on Fibromyalgia

NCT01857219
View directory record Official record
Conditions
Fibromyalgia
Interventions
Tai chi
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Oct 23, 2026, 8:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment

NCT05948930
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Progressive aerobic exercise, Adaptive cognitive training, Combined
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional

Intermittent Hypoxia Paired with High Intensity Training in Brain Injury

NCT04472442
View directory record Official record
Conditions
Brain Injuries
Interventions
Intermittent hypoxia, Sham hypoxia
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 23, 2026, 8:10 AM EDT
Recruiting Phase 2 Interventional

Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label

NCT07689773
View directory record Official record
Conditions
Olfactory Impairment
Interventions
Trigeminal Nerve Stimulation-enhanced Smell Training
Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional Results available

Computer Assisted Cognitive Rehabilitation for Persons With Multiple Sclerosis

NCT03200899
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
MAPSS-MS, Usual Care plus computer games
Behavioral · Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 60 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional Results available

Cortical and Biomechanical Dynamics of Ankle Robotics Training in Stroke

NCT01072032
View directory record Official record
Conditions
Cerebral Stroke
Interventions
Anklebot (Ankle Robot)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 85 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 30, 2016 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Problem Solving Training for Care Partners of Adults With Traumatic Brain Injury

NCT03739450
View directory record Official record
Conditions
Care Partners of Patients With Traumatic Brain Injury (TBI)
Interventions
Problem Solving Training (PST), Education
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
4
States / cities
East Hanover, New Jersey • Edison, New Jersey • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional

Brain and Behavior Correlates of Arm Rehabilitation

NCT04989920
View directory record Official record
Conditions
Stroke, Cardiovascular
Interventions
Experimental group: CIMT group (Constraint-Induced Movement Therapy)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Phase 2 Interventional

Multi-Media Imagery Program for Breast Cancer Patients (Phase II)

NCT01034215
View directory record Official record
Conditions
Breast Cancer
Interventions
Envision the Rhythms of Life Program, Envision the Rhythms of Life Program/Distance
Behavioral
Lead sponsor
Mind Matters Research LLC
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 23, 2026, 8:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Changes in the Brain as Borderline Patients Learn to Regulate Their Emotions

NCT02465697
View directory record Official record
Conditions
Borderline Personality Disorders, Avoidant Personality Disorders
Interventions
Reappraisal Training
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 31, 2017 · Synced Oct 23, 2026, 8:10 AM EDT
Not listed Not applicable Interventional

Using fMRI to Evaluate Instructional Programs for Children With Developmental Dyslexia

NCT00068835
View directory record Official record
Conditions
Developmental Dyslexia
Interventions
Lindamood-Bell training for dyslexia
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
8 Years to 12 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 23, 2026, 8:10 AM EDT