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ClinicalTrials.gov public records Last synced Oct 25, 2026, 1:49 AM EDT

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Showing 361–384 of 684 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Brain function studies Clear all
Recruiting Not applicable Interventional

Use of CereGate Therapy for Freezing of Gait in PD

NCT05292794
View directory record Official record
Conditions
Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
Interventions
CereGate Software; BSN cDBS Programmer; BSN Burst Programmer
Device
Lead sponsor
CereGate Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
7
States / cities
Redwood City, California • Aurora, Colorado • Miami, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Response to an Intervention Using Guided, At-Home Technology for the Mind

NCT05912556
View directory record Official record
Conditions
Cognition, Brain Health, Brain Structure, Brain Function
Interventions
Digital Program 1, Digital Program 2
Device
Lead sponsor
Lumos Labs, Inc.
Industry
Eligibility
25 Years to 80 Years
Enrollment
817 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neural Bases of Cognitive Rehabilitation for Brain Injury

NCT01120756
View directory record Official record
Conditions
Brain Injury
Interventions
Goal-oriented attentional self-regulation, Brain Health Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
1
States / cities
Martinez, California
Source: ClinicalTrials.gov public record
Updated Aug 2, 2019 · Synced Oct 25, 2026, 1:49 AM EDT
Recruiting Not applicable Interventional

Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

NCT07142499
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
Memory Support System, Brain Health Education
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
55 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 25, 2026, 1:49 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome

NCT06698848
View directory record Official record
Conditions
Depression, Suicide
Interventions
ketamin
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Completed Not applicable Interventional Results available

Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability

NCT01615484
View directory record Official record
Conditions
Emphysema, Chronic Obstructive Pulmonary Disease (COPD), Cystic Fibrosis, Pulmonary Fibrosis, Bronchiectasis, Sarcoidosis, Pulmonary Hypertension, Alpha-1 Antitrypsin Deficiency
Interventions
Transplantation of lungs obtained from Non-Heart-Beating Donors (NHBDs) after ex-vivo perfusion w/ STEEN Solution™, STEEN Solution™
Procedure · Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 8, 2018 · Synced Oct 25, 2026, 1:49 AM EDT
Completed Not applicable Interventional Results available

Vagal Nerve Stimulation for Treatment Resistant Major Depression

NCT04990687
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
gammaCore™
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 1, 2024 · Synced Oct 25, 2026, 1:49 AM EDT
Completed Not applicable Interventional Results available

A Study to Test the SENSE Device in Patients With Intracranial Hemorrhage

NCT03038087
View directory record Official record
Conditions
Intracerebral Hemorrhage, Stroke, Acute, Stroke Hemorrhagic
Interventions
SENSE Device
Device
Lead sponsor
Sense Diagnostics, LLC
Industry
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Oct 25, 2026, 1:49 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation and Modulation of Affect and Pain

NCT06989749
View directory record Official record
Conditions
We Are Not Studying a Disease or Condition
Interventions
Anodal tDCS, Cathodal tDCS, Sham tDCS
Other
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Hanover, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multi Modal Imaging: An MRI Study to Investigate Differences in the Structure and the Function of the Brain at Rest.

NCT01517516
View directory record Official record
Conditions
Irritable Bowel Syndrome, Cyclical Vomiting Syndrome, Ulcerative Colitis, Vulvodynia, Crohn's Disease
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 55 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2016 · Synced Oct 25, 2026, 1:49 AM EDT
Recruiting No phase listed Observational

Natural History of Cerebral Palsy Prospective Study

NCT05576948
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Months to 24 Months
Enrollment
100 participants
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 25, 2026, 1:49 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Cognitive Empathy Training on Dementia Caregivers

NCT06650527
View directory record Official record
Conditions
Caregivers of People Living With Dementia, Dementia
Interventions
Cognitive Empathy Training, Control Condition, Pre and post intervention blood spot collection, Pre and post intervention MRI session
Behavioral · Procedure
Lead sponsor
Emory University
Other
Eligibility
50 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pre-Clinical White Matter Changes and Associated Connectivity Effects in Fabry Disease

NCT03678324
View directory record Official record
Conditions
Fabry Disease
Interventions
Functional MRI and fast bound-pool fraction imaging
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Oct 25, 2026, 1:49 AM EDT
Recruiting Phase 1 Interventional

OBSERVE: A Pilot Study Of Omission Of Brain Metastasis Stereotactic Radiosurgery Following Resection With CNS-Active Systemic Therapy

NCT07655583
View directory record Official record
Conditions
Brain Metastasis, Stereotactic Radiosurgery, Resection, Systemic Therapy
Interventions
Systemic therapy
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Simultaneous FMRI and NIRS to Estimate Brain Cerebral Metabolism

NCT01825096
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2017 · Synced Oct 25, 2026, 1:49 AM EDT
Recruiting Not applicable Interventional

Targeted Accelerated TMS for Post-Traumatic Stress Disorder

NCT07245641
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD)
Interventions
Transcranial Magnetic Stimulation
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults

NCT04437251
View directory record Official record
Conditions
Vascular Accident, Brain, CVA (Cerebrovascular Accident), Gait, Hemiplegic, Spastic Lower Extremity Weakness
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
21 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Oct 25, 2026, 1:49 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Peripheral Benzodiazepine Receptors (PBR28) Brain PET Imaging With Lipopolysaccharide Challenge for the Study of Microglia Function in Alzheimer's Disease

NCT04057807
View directory record Official record
Conditions
Alzheimer Disease
Interventions
LPS
Drug
Lead sponsor
Yale University
Other
Eligibility
55 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Oct 25, 2026, 1:49 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

An Early Prospective Study of the Traq™ Device for Characterization of Binocular Ocular Function in Normal Subjects and Subjects With Recent Traumatic Brain Injury

NCT07742878
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Concussion, Binocular Visual Function, Neuro-Ophthalmology, Saccadic Eye Movements
Interventions
Binocular ophthalmic neurodiagnostic device
Device
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
12 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Waukee, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Ketamine and Guanfacine on Working Memory in Healthy Subjects

NCT01600885
View directory record Official record
Conditions
NMDA Receptor Function
Interventions
Guanfacine, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
3
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Oct 25, 2026, 1:49 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Ventricular mTOR Inhibition to Prevent Hydrocephalus After Brain Hemorrhage

NCT07662174
View directory record Official record
Conditions
Post-hemorrhagic Hydrocephalus (PHH)
Interventions
Sirolimus (Rapamune®)
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Recruiting Not applicable Interventional

Effect of Functional Electrical Stimulation (FES) on Handwriting Rehabilitation After Acquired Brain Injury (ABI)

NCT07774715
View directory record Official record
Conditions
Acquired Brain Injury Including Stroke
Interventions
Functional Electrical Stimulation (FES) on Handwriting Rehabilitation
Combination Product
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Completed No phase listed Observational

Components of Social Functioning in Survivors of Pediatric Brain Tumors

NCT03361033
View directory record Official record
Conditions
Brain Tumor, Pediatric, Medulloblastoma, Pediatric
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
8 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 25, 2026, 1:49 AM EDT
Completed Not applicable Interventional

Sleep and Girls' Emotions Study

NCT04131868
View directory record Official record
Conditions
Depression
Interventions
Typical sleep opportunity, Extended sleep opportunity
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 22 Years · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Oct 25, 2026, 1:49 AM EDT