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Showing 1–24 of 850 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Brain health Clear all
Completed No phase listed Observational Accepts healthy volunteers

A Longitudinal Examination of Aging With a Spinal Cord Injury: Cardiovascular, Cerebrovascular and Cognitive Consequences

NCT03023163
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Longitudinal
Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
28 Years to 75 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 25, 2023 · Synced Sep 4, 2026, 1:48 AM EDT
Not listed Not applicable Interventional

Brain Injury Therapy of Exercise and Enriched Environment

NCT03256643
View directory record Official record
Conditions
Brain Injuries
Interventions
Exercise, Delayed Exercise, Exercise and enrichment
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Taylor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Sep 4, 2026, 1:48 AM EDT
Recruiting Phase 2 Interventional

Long-Term Outcomes Following HBOT

NCT07732374
View directory record Official record
Conditions
Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 4, 2026, 1:48 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Alcoholism: Emotion and Thinking

NCT00300638
View directory record Official record
Conditions
Alcoholism
Interventions
Magnetic Resonance Imaging (MRI), Interviews, cognitive tests, and emotional measurements
Procedure · Behavioral
Lead sponsor
Boston University
Other
Eligibility
25 Years to 76 Years
Enrollment
599 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Sep 4, 2026, 1:48 AM EDT
Recruiting Phase 3 Interventional

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

NCT04867317
View directory record Official record
Conditions
Adult Growth Hormone Deficiency, Mild Traumatic Brain Injury
Interventions
Somatropin, Placebo
Drug · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 55 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
16
States / cities
Birmingham, Alabama • Phoenix, Arizona • San Diego, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 4, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Exercise Training on Musculoskeletal Health in Individuals With Cerebral Palsy

NCT05070117
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Exercise training
Behavioral
Lead sponsor
San Jose State University
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Sep 4, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional

Transcranial Direct Current Stimulation for Post Treatment Lyme Disease

NCT06915324
View directory record Official record
Conditions
Post-Treatment Lyme Disease
Interventions
Transcranial Direct Current Stimulation (tDCS), Cognitive training
Device · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 70 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
San Francisco, California • New York, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 4, 2026, 1:48 AM EDT
Terminated Not applicable Interventional

Effects of an Interdisciplinary Fitness and Social Engagement Intervention

NCT03160313
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
InFuSE, Patient Education/Group Discussion
Behavioral
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Sep 4, 2026, 1:48 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

El Sendero: Pathways to Health Study

NCT05551650
View directory record Official record
Conditions
Obesity, Childhood, Child Development
Interventions
Not listed
Lead sponsor
University of Southern California
Other
Eligibility
6 Years to 6 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 19, 2024 · Synced Sep 4, 2026, 1:48 AM EDT
Recruiting No phase listed Observational

Epilepsy Learning Healthcare System (ELHS)

NCT06265103
View directory record Official record
Conditions
Epilepsy, Seizure Disorder, Neurologic Disorder, Rare Diseases
Interventions
Clinical care and quality improvement
Other
Lead sponsor
Epilepsy Foundation of America
Other
Eligibility
Not listed
Enrollment
100,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2099
U.S. locations
13
States / cities
Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Sep 4, 2026, 1:48 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Transcranial Ultrasonography Using Linear 2D Imaging of the Brain

NCT01980186
View directory record Official record
Conditions
Autism, Extra-axial Fluid
Interventions
TUS transcranial 2D ultrasound
Device
Lead sponsor
Brain Treatment Center
Other
Eligibility
6 Months to 21 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
2
States / cities
Newport Beach, California • Buford, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 10, 2013 · Synced Sep 4, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional

I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms

NCT05733520
View directory record Official record
Conditions
Caregiver Burden, Alzheimer Disease
Interventions
Brain CareNotes, Dementia Guide Expert
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 4, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Sound Mind Warrior Study

NCT02328690
View directory record Official record
Conditions
Anxiety, Stress
Interventions
Binaural Beat Technology
Other
Lead sponsor
Fort Belvoir Community Hospital
Federal
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Sep 4, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurophysiological Effects on tPCS and tDCS on Healthy Subjects and on Patients With Chronic Visceral Pain

NCT02497196
View directory record Official record
Conditions
Visceral Pain, Pancreatitis, Pelvic Pain
Interventions
Active tPCS, Active tDCS, Sham tPCS, Sham tDCS
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Sep 4, 2026, 1:48 AM EDT
Completed No phase listed Observational Results available

Continued Anticonvulsants After Resolution of Neonatal Seizures: a Patient-centered Comparative Effectiveness Study

NCT02789176
View directory record Official record
Conditions
Neonatal Seizures
Interventions
Surveys, EEG
Other
Lead sponsor
University of Michigan
Other
Eligibility
0 Weeks to 24 Months
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
11
States / cities
San Francisco, California • Stanford, California • Washington D.C., District of Columbia + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Sep 4, 2026, 1:48 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Auditory EEG and Behavioral Assessments in Individuals With Rett Syndrome

NCT07569445
View directory record Official record
Conditions
Rett Syndrome
Interventions
Electroencephalogram (EEG) Recording
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
2 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 4, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer

NCT02290834
View directory record Official record
Conditions
Impaired Cognition, Chemo-brain, Breast Cancer
Interventions
Cognitive, functional and subjective assessments, MRI, PET Scan
Other · Device · Radiation
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Salem, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 4, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketogenic Intervention in Depression

NCT06080932
View directory record Official record
Conditions
Depression, Ketosis
Interventions
Ketogenic Diet, NIH Toolbox, gradCPT, Resting-state fMRI, Task-fMRI, CGM/CKM, Blood Draw, Sleep Monitoring, Ketone/Glucose Monitoring, Body Composition, PHQ-9, WHO-5, SKID
Other · Biological · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 4, 2026, 1:48 AM EDT
Completed Not applicable Interventional Results available

Aerobic Exercise in Parkinson's Disease

NCT03808675
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Aerobic walking, Usual care with PD specific health education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 4, 2026, 1:48 AM EDT
Completed Phase 2 Interventional

Pain and Stress Management for Fibromyalgia

NCT01287481
View directory record Official record
Conditions
Fibromyalgia
Interventions
Stress and Emotions, Thoughts and Behaviors, Brain and Body
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 75 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
3
States / cities
Ann Arbor, Michigan • Detroit, Michigan • Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Sep 4, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional

Systematic Light Exposure in Pediatric Brain Tumor Survivors

NCT05340881
View directory record Official record
Conditions
Brain Tumor
Interventions
Bright Light Exposure, Dim Light Exposure, Cognitive Assessment
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
10 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 4, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise and Endocannabinoids for Brain and Mental Health

NCT06808490
View directory record Official record
Conditions
Children, Adolescents
Interventions
Moderate Intensity Exercise, Light Intensity Stretching, Seated Meditation
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
9 Years to 17 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 4, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional

Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain

NCT07137715
View directory record Official record
Conditions
Chronic Pain, Back Pain, Back Pain Lower Back Chronic, Neck Pain
Interventions
Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 4, 2026, 1:48 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Integrity in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation

NCT01820117
View directory record Official record
Conditions
Hodgkin Lymphoma
Interventions
Neurocognitive Evaluation, Quantitative Brain Imaging, Neurologic Evaluation, Health Questionnaire, Vascular Testing, Cardiopulmonary Exercise Testing, Echocardiography, Pulmonary Function Testing, Serum Biomarkers, Ophthalmology Examination
Other · Procedure
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
416 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Sep 4, 2026, 1:48 AM EDT