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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Brain-computer interface Clear all
Completed No phase listed Observational Results available

A Clinical Demonstration of EEG Brain-computer Interface for ALS Patients

NCT00786032
View directory record Official record
Conditions
ALS (Amyotrophic Lateral Sclerosis)
Interventions
BCI Device
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 79 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
5
States / cities
West Haven, Connecticut • Albany, New York • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2015 · Synced Sep 5, 2026, 10:52 PM EDT
Enrolling by invitation Not applicable Interventional

Control of Assistive Devices Via Brain-Computer Interface Technology

NCT06710626
View directory record Official record
Conditions
Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS), Quadriplegia, Spinal Cord Injury (SCI), Spinal Cord Injury Cervical
Interventions
Assistive Robotic Arm
Device
Lead sponsor
Neuralink Corp
Industry
Eligibility
Not listed
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Attention in Elderly Using a Brain-Computer-Interface

NCT07441122
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
transcranial electrical stimulation, Mindfulness Meditation
Device · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Austin, Texas • Georgetown, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

P300 Brain Computer Interface Keyboard to Operate Assistive Technology

NCT00860951
View directory record Official record
Conditions
Healthy, Amyotrophic Lateral Sclerosis, Neuromuscular Disease, Spinal Cord Injury, Cerebral Palsy
Interventions
Brain Computer Interface Keyboard
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
2
States / cities
Ann Arbor, Michigan • Albany, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2015 · Synced Sep 5, 2026, 10:52 PM EDT
Enrolling by invitation Not applicable Interventional

mindBEAGLE: Unlocking Functional Communication for Patients With Disorders of Consciousness

NCT06426602
View directory record Official record
Conditions
Disorders of Consciousness
Interventions
mindBEAGLE daily device use
Device
Lead sponsor
Amy Wagner
Other
Eligibility
16 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Using EEG Operant Conditioning to Improve Trait Self-Control and Promote Healthy Behavior

NCT01801254
View directory record Official record
Conditions
Obesity, Type II Diabetes, Cardiovascular Disease, Health Behavior
Interventions
STRIDES, Sham Control
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)

NCT06094205
View directory record Official record
Conditions
Anarthria, Dysarthria, Tetraplegia, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis, Brain Stem Infarctions, Locked-in Syndrome, Muscular Dystrophies
Interventions
BrainGate Neural Interface System
Device
Lead sponsor
Leigh R. Hochberg, MD, PhD.
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 30, 2025 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Providing Brain Control of Extracorporeal Devices to Patients With Quadriplegia

NCT01849822
View directory record Official record
Conditions
Tetraplegia
Interventions
Neural Prosthetic System
Device
Lead sponsor
Richard A. Andersen, PhD
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
3
States / cities
Downey, California • Los Angeles, California • Pasadena, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

NCT07357428
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Neuromuscular Disease, Stroke, Tetraplegia/Tetraparesis, Cervical Spinal Cord Injury, Dysarthria
Interventions
Connexus Brain-Computer Interface
Device
Lead sponsor
Paradromics
Industry
Eligibility
22 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
3
States / cities
Sacramento, California • Boston, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Computer Interface Control of a Robotic Device

NCT02069938
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

A Brain Centered Neuroengineering Approach for Motor Recovery After Stroke: Combined rTMS and BCI Training

NCT02132520
View directory record Official record
Conditions
Hemiparesis, Stroke
Interventions
rTMS, BCI Training
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

BCI-FES Therapy for Stroke Rehabilitation

NCT04279067
View directory record Official record
Conditions
Ischemic Stroke, Hemorrhagic Stroke
Interventions
BCI-FES dorsiflexion therapy, Physiotherapy one hour, Physiotherapy two hours
Device · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

An In-home Study of Brain Computer Interfaces

NCT01123200
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Brain Computer Interface for Wheelchair Tilt Control
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-Invasive Brain Signal Training to Induce Motor Control Recovery After Stroke

NCT00746525
View directory record Official record
Conditions
Stroke
Interventions
Surface functional electrical stimulation (FES), Motor learning, Brain computer interface (BCI) training
Other
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
22 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 22, 2017 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI)

NCT06406855
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
BCI-TSCS
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)

NCT00809224
View directory record Official record
Conditions
ALS, Amyotrophic Lateral Sclerosis
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 15, 2016 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS

NCT06810219
View directory record Official record
Conditions
ALS (Amyotrophic Lateral Sclerosis)
Interventions
Cognixion ONE
Device
Lead sponsor
Cognixion
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment of Chronic Stroke With IpsiHand

NCT02552368
View directory record Official record
Conditions
Stroke
Interventions
IpsiHand Device
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 88 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 16, 2018 · Synced Sep 5, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Chiropractic Adjustments on Brain Function Using Quantitative Encephalography

NCT01953614
View directory record Official record
Conditions
Brain Function
Interventions
Chiropractic adjustment, Sham adjustment
Other
Lead sponsor
Life University
Other
Eligibility
10 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Sep 5, 2026, 10:52 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Moving a Paralyzed Hand Through Use of a Brain-Computer Interface

NCT00242242
View directory record Official record
Conditions
Stroke
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 24, 2019 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive BCI-controlled Assistive Devices

NCT05183152
View directory record Official record
Conditions
Motor Disorders, Healthy, Spinal Cord Injuries, Muscular Diseases, Motor Neuron Disease, Stroke, Traumatic Brain Injury, Movement Disorders, Multiple Sclerosis
Interventions
NMES Feedback, Visual Feedback, TESS
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Nursing Students' Brain/MS Immersive Three-Dimensional Learning Activity

NCT07538063
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
The immersive 360-degree educational video, The slideshow (PowerPoint) educational presentation
Other
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Fairfield, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Recruiting No phase listed Observational

Understanding and Preventing Cortical Mechanisms of Chemotherapy-induced Peripheral Neuropathy

NCT06389721
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Electroencephalogram (EEG)
Diagnostic Test
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 5, 2026, 10:52 PM EDT
Terminated Not applicable Interventional

Detection of Area of Ischemia in Patients With Subacute Stroke Via a Hybrid EEG-fNIRS Brain-computer Interface

NCT03034902
View directory record Official record
Conditions
Stroke
Interventions
Combined EEG and fNIRS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 5, 2026, 10:52 PM EDT