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ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:34 AM EDT

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Showing 73–96 of 256 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Brain-level condition Clear all
Recruiting Phase 2Phase 3 Interventional

Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder

NCT06807918
View directory record Official record
Conditions
Alcohol Use Disorder, Ketosis
Interventions
Kenetik, magnetic resonance imaging scan, Alcohol bar lab, Placebo beverage
Dietary Supplement · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Teen Brain Training (TBT)

NCT06183580
View directory record Official record
Conditions
Suicide, Attempted, Suicide, Ideation, Depression
Interventions
neurofeedback training involving dACC, neurofeedback training involving amygdala
Other
Lead sponsor
University of Minnesota
Other
Eligibility
11 Years to 18 Years
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Terminated Not applicable Interventional

SMARTfit Training for Parkinson's Disease

NCT03921359
View directory record Official record
Conditions
Parkinson Disease, Exercise Training, Cognitive Change
Interventions
SMARTfit training, Conventional physical training
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
50 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 22, 2026, 3:34 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Polycystic Ovary Syndrome (PCOS) and Sleep Apnea

NCT00203996
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Interventions
continuous positive airway pressure (CPAP), depot leuprolide plus estrogen/progestin replacement, pioglitazone, REM frag, SWS supp
Device · Drug · Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PET and MRI Brain Imaging of Bipolar Disorder

NCT01880957
View directory record Official record
Conditions
Bipolar Disorder, Bipolar Depression, Unipolar Depression
Interventions
Lithium, Lamotrigine
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 65 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Training in Children With/At-risk for Attention-Deficit/Hyperactivity Disorder and Executive Function Impairment

NCT02588365
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Brain Training (Active), Brain Training (Passive), Brain Training (Active or Passive)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 5 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Oct 22, 2026, 3:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Characterization of the Functional and Structural Development of the Human Neonatal Brain From 30 Wks to 45 Wks ga

NCT02170142
View directory record Official record
Conditions
Human Development
Interventions
MRI
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
30 Weeks to 45 Weeks
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional Results available

Aerobic Exercise in Parkinson's Disease

NCT03808675
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Aerobic walking, Usual care with PD specific health education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting Not applicable Interventional

Mild TBI Assessment & Rehabilitation

NCT02920788
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Goal-Oriented Attentional Self-Regulation (GOALS), Brain Health Education (BHE), fMRI
Behavioral · Other · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting No phase listed Observational

fMRI Accelerated TMS Depression

NCT06562153
View directory record Official record
Conditions
Depression
Interventions
Neuroimaging with Magnetic Resonance Imaging (MRI)
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting Phase 3 Interventional

Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3

NCT05834478
View directory record Official record
Conditions
Withdrawal Symptoms, Opioid Use Disorder, Opioid Use
Interventions
Transcutaneous Cervical Vagal Nerve Stimulation, Sham Stimulation, [F-18]Fallypride
Device · Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 75 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Quantifying Energetic Demands of Walking for People With Cerebral Palsy

NCT04303078
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Varying levels of harness support during walking
Other
Lead sponsor
University of Washington
Other
Eligibility
8 Years to 17 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Not listed Phase 1Phase 2 Interventional

Biomarker Study: Heart Failure Patients at Risk

NCT05336175
View directory record Official record
Conditions
Heart Failure NYHA Class II, Heart Failure NYHA Class III, Heart Failure NYHA Class IV
Interventions
Angiotensin 1-7, Saline solution
Drug
Lead sponsor
University of Arizona
Other
Eligibility
45 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Phoenix, Arizona • Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 20, 2022 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech

NCT07459803
View directory record Official record
Conditions
Stuttering, Developmental, Dyslexia, Healthy Participants
Interventions
Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation, Sustained F0 auditory feedback perturbation, Reflexive somatosensory perturbation, Anodal tCS targeting pSTG and vSSC, Anodal tCS targeting left or right vPMC, Sham tCS targeting pSTG or vSSC, Sham tCS targeting left vPMC or right vPMC
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting Not applicable Interventional

Safety and Tolerability of Patterned Stimulation for DBS in the Home Setting

NCT07410598
View directory record Official record
Conditions
Parkinson Disease, Deep Brain Stimulation
Interventions
Biphasic deep brain stimulation, Conventional deep brain stimulation, Theta burst deep brain stimulation, Multi frequency deep brain stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 4 Interventional

Investigation of Lithium on Signal Transduction, Gene Expression and Brain Myo-Inositol Levels in Manic Patients

NCT00870311
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Lithium Carbonate
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2004
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 27, 2009 · Synced Oct 22, 2026, 3:34 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

A Study Evaluating Potential Screening Tools for Detecting Parkinson Disease

NCT00387075
View directory record Official record
Conditions
Parkinson Disease
Interventions
[123I]β-CIT and SPECT imaging, [123I]β-CIT
Procedure · Drug
Lead sponsor
Institute for Neurodegenerative Disorders
Other
Eligibility
50 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 29, 2022 · Synced Oct 22, 2026, 3:34 AM EDT
Withdrawn No phase listed Observational

The Natural History of Procalcitonin in Hemorrhagic Stroke

NCT01498705
View directory record Official record
Conditions
Intraventricular Hemorrhage, Intracerebral Hemorrhage
Interventions
Procalcitonin level
Other
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Active, not recruiting Not applicable Interventional

Acceptability and Efficacy of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Back Pain

NCT05820204
View directory record Official record
Conditions
Pain, Chronic, Back Pain
Interventions
Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual care
Behavioral · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Not listed No phase listed Observational

Biomarkers of Independent Walking Post-Stroke

NCT05004389
View directory record Official record
Conditions
Stroke, Acute, Gait, Hemiplegic
Interventions
MRI, blood draw, Clinical assessments
Diagnostic Test · Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Oct 22, 2026, 3:34 AM EDT
Not listed Phase 1 Interventional

Retrain Your Brain in Children/Adolescents With Bipolar Disorder: A Pilot Study

NCT01954680
View directory record Official record
Conditions
Bipolar Disorder, Pediatric Bipolar Disorder, Childhood-onset Bipolar Disorder
Interventions
COGFLEX-skill building levels, COGFLEX-control condition
Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
7 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
East Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional

Electrophysiological Recordings of Deep Brain Stimulation in the Basal Ganglia

NCT03088592
View directory record Official record
Conditions
Parkinson Disease
Interventions
Deep Brain Stimulation
Device
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years to 85 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 28, 2022 · Synced Oct 22, 2026, 3:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Brain Mechanisms of Human Motivation

NCT01976975
View directory record Official record
Conditions
Major Depressive Disorder, Bipolar Disorder
Interventions
Not listed
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

NCT06960096
View directory record Official record
Conditions
Deep Brain Stimulation, Parkinson Disease
Interventions
DBS combined with fMRI
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 22, 2026, 3:34 AM EDT