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ClinicalTrials.gov public records Last synced Sep 29, 2026, 11:41 AM EDT

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Showing 1–24 of 228 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Breast Reconstruction (Mammaplasty) Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

The Use of Pecs Blocks in Combination With Exparel in Breast Reconstruction Surgery

NCT05171179
View directory record Official record
Conditions
Mammaplasty
Interventions
Breast Reconstruction (Mammaplasty), Pecs blocks, Exparel, Bupivacaine
Procedure · Device · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Sep 29, 2026, 11:41 AM EDT
Recruiting Not applicable Interventional

NPWT Reduction Mammaplasty

NCT06725459
View directory record Official record
Conditions
Healthy, Macromastia, Negative Pressure Therapy, Mammaplasty, Wound Healing
Interventions
Prophylactic ciNPWT, Standard Adhesive Dressing
Device · Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 29, 2026, 11:41 AM EDT
Recruiting Phase 1 Interventional

Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon

NCT07264790
View directory record Official record
Conditions
Breast Reconstruction, Perfusion; Complications, High Risk for Breast Cancer, Genetic Predisposition
Interventions
Minoxidil, Hair mousse
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 29, 2026, 11:41 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of NATRELLE® 410 Highly Cohesive, Anatomically Shaped, Silicone-filled X-Style and L-Style Breast Implants

NCT01785069
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped, silicone-filled breast implants with low projection or extra-full projection
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
355 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
29
States / cities
Campbell, California • Palo Alto, California • Pleasanton, California + 23 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Sep 29, 2026, 11:41 AM EDT
Completed Not applicable Interventional

Comparing AlloDerm and DermACELL in Breast Reconstruction

NCT04710537
View directory record Official record
Conditions
Acellular Dermal Matrix in Breast Reconstruction
Interventions
AlloDerm, DermACELL
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Sep 29, 2026, 11:41 AM EDT
Completed Phase 4 Interventional Results available

Use of Pulsed Electromagnetic Fields (PEMF) After Breast Reconstruction Surgery

NCT01262599
View directory record Official record
Conditions
Other Reconstructive Surgery
Interventions
Sham PEMF Device, Ivivi Torino II PEMF Device
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Sep 29, 2026, 11:41 AM EDT
Completed No phase listed Observational

Patient Preferences for Breast Reconstruction After Mastectomy

NCT01488357
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
21 Years and older · Female only
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Sep 29, 2026, 11:41 AM EDT
Completed Phase 4 Interventional

A Comparison of Dermal Autograft to AlloDerm in Breast Reconstruction

NCT01561287
View directory record Official record
Conditions
Mastectomy Related Lymphedema, Breast Reconstruction, Breast Cancer
Interventions
Dermal Autograft, AlloDerm
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 10, 2016 · Synced Sep 29, 2026, 11:41 AM EDT
Active, not recruiting Not applicable Interventional Results available

Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma

NCT03422003
View directory record Official record
Conditions
Breast Cancer
Interventions
Radiation Therapy
Radiation
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
15
States / cities
San Francisco, California • Stanford, California • Edwards, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Sep 29, 2026, 11:41 AM EDT
Completed Not applicable Interventional Results available

Blossom Smart Expander Technology in Breast Reconstruction in Participants With Breast Cancer Undergoing Mastectomy

NCT03657069
View directory record Official record
Conditions
Breast Carcinoma, Breast Disorder
Interventions
Blossom, Breast-Q -Reconstruction module (preoperative) version 2.0 satisfaction with breasts questionnaire
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2024 · Synced Sep 29, 2026, 11:41 AM EDT
Completed Not applicable Interventional

Development of a Questionnaire to Evaluate Patient Expectations for Breast Reconstruction in Women With Breast Cancer or Other Conditions

NCT00471601
View directory record Official record
Conditions
Breast Cancer
Interventions
counseling intervention, questionnaire administration, psychosocial assessment and care, quality-of-life assessment
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
357 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2023
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 1, 2024 · Synced Sep 29, 2026, 11:41 AM EDT
Recruiting Not applicable Interventional

A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery

NCT04891510
View directory record Official record
Conditions
Mastectomy, Mammaplasty, Breast Reconstruction
Interventions
REVOLVE Advanced Adipose System, LipoGrafter, Viality
Device · Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 29, 2026, 11:41 AM EDT
Completed No phase listed Observational

Evaluating the Effectiveness and Outcomes of Silicone Breast Prosthetics

NCT00594490
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2013
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Sep 29, 2026, 11:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of One-port and Two-port Tissue Expanders for Breast Reconstruction

NCT02725801
View directory record Official record
Conditions
Breast Cancer
Interventions
Allergen one-port tissue expander placement, AlloX2 two-port tissue expander placement
Device
Lead sponsor
Lesley Wong
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Sep 29, 2026, 11:41 AM EDT
Completed No phase listed Observational Results available

Immediate Postmastectomy Breast Reconstruction (Strattice Breast)

NCT00619762
View directory record Official record
Conditions
Breast Cancer
Interventions
LTM - a porcine-based surgical mesh
Device
Lead sponsor
LifeCell
Industry
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Chicago, Illinois • Great Neck, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2016 · Synced Sep 29, 2026, 11:41 AM EDT
Active, not recruiting Not applicable Interventional

Split Chest Breast Neurotization

NCT05757778
View directory record Official record
Conditions
Breast Implant; Complications
Interventions
Sensory Nerve Coaptation
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 29, 2026, 11:41 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Study on Pain After Breast Reconstruction

NCT06627582
View directory record Official record
Conditions
Mastectomy, Mastectomy Patient, Mastectomy and Breast Reconstruction, Breast Reconstruction, Breast Reconstruction After Mastectomy, Postmastectomy Pain
Interventions
PROMIS Scale v2.0 - Pain Intensity 3a, PROMIS 29+2, PROMIS Scale v2.0 - Nociceptive Pain Quality 5a, PROMIS Scale v2.0 - Neuropathic Pain Quality 5a
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
274 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 29, 2026, 11:41 AM EDT
Completed Not applicable Interventional Results available

Tissue Expander Breast Reconstruction Study on Breast Volume and Shape Change

NCT01222390
View directory record Official record
Conditions
Contour Irregularity of Reconstructed Breast
Interventions
Contour Profile Tissue Expander
Device
Lead sponsor
Northwestern University
Other
Eligibility
25 Years to 85 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Sep 29, 2026, 11:41 AM EDT
Recruiting Not applicable Interventional

Pulsed Lavage in Implant-Based Breast Reconstruction

NCT05585710
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Pulsed Lavage Washout, Implant-based breast reconstruction, Bilateral or unilateral mastectomy, Tissue expander, Acellular dermal matrix
Other · Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 29, 2026, 11:41 AM EDT
Completed Not applicable Interventional Results available

Cosmetic Result/Toxicity in Post-Mastectomy Immediate Reconstruction Expander+RT

NCT01664091
View directory record Official record
Conditions
Breast Cancer
Interventions
post-mastectomy radiation therapy (PMRT), tissue expander (TE), acellular dermal matrix (ADM)
Radiation · Device
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Sep 29, 2026, 11:41 AM EDT
Not yet recruiting Not applicable Interventional

Thermal Preconditioning in Mastectomy Patients With Immediate Breast Reduction

NCT07516483
View directory record Official record
Conditions
Breast Reconstruction After Mastectomy
Interventions
1 Cycle Thermal Preconditioning, 3 Cycles Thermal Preconditioning, No Intervention
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Sep 29, 2026, 11:41 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

NATRELLE® 410 X-Style and L-Style Breast Implants Continued Access Study

NCT01870869
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped, silicone-filled breast implants with low height/projection or extra-full projection
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,951 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
58
States / cities
Beverly Hills, California • Campbell, California • Long Beach, California + 45 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2020 · Synced Sep 29, 2026, 11:41 AM EDT
Completed No phase listed Observational

SPY Intra-Operative Angiography & Skin Perfusion in Immediate Breast Reconstruction w/ Implants

NCT01315119
View directory record Official record
Conditions
Breast Cancer
Interventions
SPY Intra-Operative Angiography
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Sep 29, 2026, 11:41 AM EDT
Withdrawn Phase 1 Interventional

19F Hot Spot MRI of Human Adipose-derived Stem Cells for Breast Reconstruction

NCT02035085
View directory record Official record
Conditions
Breast Cancer
Interventions
CS-1000 labeled SVF cells
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Lutherville-Timonium, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Sep 29, 2026, 11:41 AM EDT