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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Brief CBT-I Clear all
Not yet recruiting Not applicable Interventional

Evaluating the Impact of Digital Behavioral Interventions to Address Insomnia and Depression in Breast Cancer Survivors Using an Adaptive Design

NCT07721064
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Digital Insomnia Program, Digital Mental Health Program, Psychoeducation
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
747 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional

Electrophysiologic Changes in Blacks Treated With CBT for Insomnia

NCT02741336
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Self-Monitoring
Behavioral
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 12, 2017 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional

Sleep Well: Digital Insomnia Treatment Program For Physicians

NCT05289596
View directory record Official record
Conditions
Sleep Disturbance, Insomnia, Stress, Psychological, Anxiety, Burnout, Professional
Interventions
Sleep Healthy Using the Internet (SHUT-i)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety

NCT04424407
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
25 Years to 60 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional

A Single-Session Online Insomnia Intervention

NCT04988464
View directory record Official record
Conditions
Insomnia
Interventions
Sleep Scholar, Building Healthy Habits
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Sep 10, 2026, 4:40 PM EDT
Recruiting Not applicable Interventional

Efficacy of the I-CARE Digital Health Intervention

NCT07150832
View directory record Official record
Conditions
Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
Interventions
Improving Care, Accelerating Recovery & Education (ICARE)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
New Haven, Connecticut • Hanover, New Hampshire • Lebanon, New Hampshire + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 10, 2026, 4:40 PM EDT
Terminated Not applicable Interventional

Treatment of Depression Using a Mobile Application in the Dominican Republic

NCT04948996
View directory record Official record
Conditions
Depression Mild, Depression Moderate
Interventions
El Buen Consejo Móvil- Group (EBCM-G), El Buen Consejo Móvil- Individual (EBCM-I)
Behavioral
Lead sponsor
Northern Illinois University
Other
Eligibility
18 Years to 110 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
DeKalb, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 7, 2022 · Synced Sep 10, 2026, 4:40 PM EDT
Enrolling by invitation Not applicable Interventional

Brief Cognitive Behavioral Therapy Replication Trial

NCT03769259
View directory record Official record
Conditions
Suicide, Attempted, Suicidal Ideation
Interventions
Brief Cognitive Behavioral Therapy (BCBT), Present-Centered Therapy (PCT), Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Jacksonville, North Carolina • Columbus, Ohio • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Preventing Persistent Post-Surgical Pain and Dysfunction

NCT03965897
View directory record Official record
Conditions
Pain, Function, Anxiety, Depression, Arthroplasty, Replacement, Knee, Veterans
Interventions
Acceptance and Commitment Therapy (ACT), Attention Control (AC)
Behavioral · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)

NCT02248675
View directory record Official record
Conditions
Insomnia, Depression, Posttraumatic Stress Disorder, Suicidal Ideation
Interventions
CBT-I, TAU
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Sep 10, 2026, 4:40 PM EDT
Enrolling by invitation Not applicable Interventional

SHADES Mechanistic Trial

NCT06041581
View directory record Official record
Conditions
Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance, Sleep Disorder, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Stroke, Autonomic Dysfunction, Systemic Inflammatory Response, Metabolic Disease
Interventions
Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I, Active Control: Sleep Education/Hygiene, Symptom Monitoring, and Usual Primary Care
Behavioral · Other
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RCT for Innovating Stress-related eHealth

NCT05305235
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Sexual Assault, Pain
Interventions
RISE Guide, Relaxation Control
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional

Subjective Sleep Quality of Patients With Chronic Insomnia

NCT06550388
View directory record Official record
Conditions
Insomnia Chronic
Interventions
Nutritional Education, Physical Activity
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional

A Randomized Clinical Trial Testing the Effectiveness of Telemental Health for Suicidal Patients

NCT04844294
View directory record Official record
Conditions
Suicide, Suicidal Ideation, Suicide Attempt
Interventions
Brief Cognitive Behavioral Therapy (BCBT), Present-Centered Therapy (PCT)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Sep 10, 2026, 4:40 PM EDT
Active, not recruiting Not applicable Interventional

Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone Support

NCT05473598
View directory record Official record
Conditions
Alcoholism
Interventions
Stand Down app, Peer-Supported Stand Down, Usual Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Palo Alto, California • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional

Effects of Brief Training on Craving Regulation

NCT02153749
View directory record Official record
Conditions
Nicotine Addiction
Interventions
Cognitive Regulation of Craving, Mindfulness-Based Regulation of Craving
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 12, 2020 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Treating Co-Morbid Sleep Difficulties in Veterans With Posttraumatic Stress Disorder (PTSD): A Pilot Study

NCT00734799
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Insomnia
Interventions
Sleep Intervention for PTSD (SIP).
Behavioral
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
Not listed
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2015 · Synced Sep 10, 2026, 4:40 PM EDT
Active, not recruiting Not applicable Interventional

Improving Care, Accelerating Recovery and Education

NCT06233747
View directory record Official record
Conditions
Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
Interventions
Improving Care, Accelerating Recovery & Education (ICARE)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Withdrawn Not applicable Interventional

A Sleep Extension Pilot Study in Adults With Obesity

NCT05747105
View directory record Official record
Conditions
Obesity, Sleep, Weight, Body, Eating Behavior, Blood Pressure, Quality of Life
Interventions
Sleep Extension
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia

NCT01549899
View directory record Official record
Conditions
Insomnia
Interventions
In-person Cognitive Behavioral Therapy of Insomnia, Internet Cognitive Behavioral Therapy of Insomnia
Behavioral
Lead sponsor
Daniel J. Taylor, Ph.D.
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 10, 2026, 4:40 PM EDT
Terminated Not applicable Interventional

Brief Versus Standard Cognitive Behavioral Therapy for Insomnia in Veterans

NCT05724498
View directory record Official record
Conditions
Insomnia
Interventions
Brief CBT-I, Standard CBT-I
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
San Diego, California • Canandaigua, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional

Hypertension With Unsatisfactory Sleep Health

NCT02508129
View directory record Official record
Conditions
Insomnia, Hypertension
Interventions
Brief Behavioral Treatment for Insomnia, Sleep Healthy Using the Internet, Enhanced Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 100 Years
Enrollment
542 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts

NCT03603717
View directory record Official record
Conditions
Insomnia, Suicidal Ideation
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Buffalo, New York • Canandaigua, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2024 · Synced Sep 10, 2026, 4:40 PM EDT
Completed No phase listed Observational Results available

Enhancing Access to Insomnia (EASI) Care in VA PCMHI Clinics

NCT04350866
View directory record Official record
Conditions
Chronic Insomnia
Interventions
Expert Recommendations for Implementing Change bundle of strategies, Brief Behavioral Treatment for Insomnia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
277,920 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 10, 2026, 4:40 PM EDT