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Showing 1–24 of 75 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Brief Intervention (SBIRT) Clear all
Completed Not applicable Interventional

Alcohol Drinking as a Vital Sign

NCT01135654
View directory record Official record
Conditions
Unhealthy Drinking, Alcohol Dependence
Interventions
Training & Tech Support for Delivery of Alcohol Screening, Brief Intervention, and Referral To Treatment
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
639,613 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Results available

An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients

NCT02531594
View directory record Official record
Conditions
Smoking Cessation
Interventions
SBIRT, HHC
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
770 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

To Reach Unrestricted Services for Transgender Women

NCT03877497
View directory record Official record
Conditions
Transgender Women, Substance Abuse, Hiv
Interventions
Adapted SBIRT-T for transgender women
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years and older · Male only
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Miami, Florida • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional

Screening, Brief Intervention, and Referral to Treatment for Offenders

NCT01683643
View directory record Official record
Conditions
Substance Use, HIV Infections
Interventions
SBIRT, Control Group
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 100 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional

Technologically-Augmented Referrals to Mitigate Addiction Consequences

NCT04401215
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Technology Augmented Treatment for Screening, Brief Intervention, Referral, and Treatment (SBIRT)
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
21 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Spokane Valley, Washington
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Sep 23, 2026, 6:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

NCT06005298
View directory record Official record
Conditions
Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
Interventions
Screening, Brief Intervention, Referral to Treatment (SBIRT)
Behavioral
Lead sponsor
Shirish S Barve
Other
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 21, 2024 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Results available

Feasibility of SBIRT-PN

NCT03057119
View directory record Official record
Conditions
Substance Use, HIV/AIDS, Older Adults, Behavioral Intervention, Infectious Disease
Interventions
Psycho-educational content (5 Minutes), Readiness Assessment (10 minutes), Goal-Setting (5 minutes), Identifying and prioritizing needs (5 minutes), Explanation of Peer Navigator and Session wrap (5 minutes)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 85 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida • Lake City, Florida
Source: ClinicalTrials.gov public record
Updated Sep 10, 2023 · Synced Sep 23, 2026, 6:10 AM EDT
Withdrawn Phase 1Phase 2 Interventional

cSBIRT to Reduce Teen Tobacco, Alcohol and Drug Use

NCT01275391
View directory record Official record
Conditions
Tobacco Abuse, Alcohol Abuse, Drug Abuse
Interventions
Computer Screening, Brief Intervention, Referral toTreatment
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Phase 3 Interventional Results available

Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps)

NCT03512418
View directory record Official record
Conditions
HIV Infections, Substance Use Disorders
Interventions
PrEPsteps, Digital pill, Truvada
Behavioral · Device · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Boylston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of an Evidence-based Stepped Care System for Alcohol and Other Drug Use Problems Among Congolese Refugees in Zambia

NCT05471921
View directory record Official record
Conditions
Alcohol and Substance-Related Mental Disorders
Interventions
SBIRT, Treatment as usual
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
15 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Effectiveness of the FaCES Adolescent SBIRT Intervention

NCT04097964
View directory record Official record
Conditions
Adolescent Health Services, Adolescent Behavior
Interventions
brief intervention, treatment as usual
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
12 Years to 17 Years
Enrollment
1,226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
4
States / cities
Lordsburg, New Mexico • Silver City, New Mexico • Adamsville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Choices4Health: Intervention to Prevent Substance-exposed Pregnancy

NCT03633149
View directory record Official record
Conditions
Prenatal Alcohol Exposure, Prenatal Tobacco Exposure, Prenatal Marijuana Exposure
Interventions
Computer tablet-delivered C4H, Person-delivered C4H, Brief Advice
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care

NCT04935606
View directory record Official record
Conditions
Drug Use
Interventions
Usual Care, QUIT Intervention (doctor brief advice, video doctor, health coaching sessions at 2- and 6-weeks), QUIT-Mobile (QUIT Intervention plus weekly mobile-web app or text message weekly self-monitoring, automated feedback over 12 months)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
457 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
5
States / cities
Long Beach, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Results available

Pragmatic RCT of SBIRT-PM

NCT04062214
View directory record Official record
Conditions
Substance Use Disorders, Pain
Interventions
SBIRT-PM
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 100 Years
Enrollment
1,101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
9
States / cities
New Haven, Connecticut • West Haven, Connecticut • Augusta, Maine + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Phase 1 Interventional Results available

Computer-delivered Screening and Brief Intervention for Alcohol Use in Pregnancy

NCT01643044
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Nutrition time control/placebo intervention, Computer-delivered, brief intervention on alcohol use
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 31, 2014 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Results available

Treating Low-Income Smokers in the Hospital Emergency Department

NCT01328431
View directory record Official record
Conditions
Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
Interventions
Brief Intervention with NRT Initiation
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 3, 2014 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Results available

Screening Brief Intervention Referral to Treatment (SBIRT) in New Mexico

NCT01131520
View directory record Official record
Conditions
Drug Abuse, HIV Risk Behavior
Interventions
Computerized brief intervention, Counselor delivered brief intervention
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 11, 2017 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Share Health Study: Teen Social Connections and Health (Phase 2)

NCT03842540
View directory record Official record
Conditions
Contraception
Interventions
SpeakOut, PartyWise
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years to 20 Years · Female only
Enrollment
1,099 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional

Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments

NCT01207791
View directory record Official record
Conditions
Drug Abuse
Interventions
screening, assessment, referral, Brief intervention, booster sessions
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
1,285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
7
States / cities
Miami, Florida • Boston, Massachusetts • Albuquerque, New Mexico + 4 more
Source: ClinicalTrials.gov public record
Updated May 23, 2013 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional

Impact of Personalized Feedback Alone on Substance Use Behaviors

NCT01501318
View directory record Official record
Conditions
Substance Abuse
Interventions
Personalized feedback report, Personalized feedback report plus education
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 105 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer-Assisted Tobacco Interventions in Dental Offices

NCT01584882
View directory record Official record
Conditions
Smoking
Interventions
CATI Tool
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 100 Years
Enrollment
548 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Sep 23, 2026, 6:10 AM EDT
Completed Phase 2 Interventional

Screening and Brief Intervention in the ED Among Mexican-origin Young Adults

NCT02056535
View directory record Official record
Conditions
Problem Drinking, Alcohol Dependence
Interventions
Brief Motivational Intervention
Behavioral
Lead sponsor
Public Health Institute, California
Other
Eligibility
18 Years to 30 Years
Enrollment
698 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2014 · Synced Sep 23, 2026, 6:10 AM EDT
Terminated Not applicable Interventional

Mobile Technologies Extending Reach of Primary Care for Substance Use Disorders

NCT06208839
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
SBIRT/eIntervention for those with moderate risk drug or alcohol use, SBIRT/eIntervention those assessed with high risk., SBIRT/TAU for those with moderate risk drug or alcohol use, SBIRT/TAU for those assessed with high risk.
Device · Other
Lead sponsor
Chess Mobile Health
Industry
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 23, 2026, 6:10 AM EDT
Completed No phase listed Observational

Implementation and Evaluation of SBIRT

NCT03560076
View directory record Official record
Conditions
Substance Use Disorders
Interventions
SBIRT Training and Implementation Strategies
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
2,562 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Sep 23, 2026, 6:10 AM EDT