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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Trauma Resilience and Recovery Program
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Washington, Virginia
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Depression, Post-Traumatic Stress Disorder, Functional Status
Interventions
Vets Prevail
Behavioral
Lead sponsor
Prevail Health Solutions, LLC
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Completed No phase listed Observational Accepts healthy volunteers

Brain Injury Outcomes (BIO) Study

NCT00724607
Conditions
Brain Concussion, Posttraumatic Stress Disorder, Dementia
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 59 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2024
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder, Stimulant Use & Co-occuring Opioid Use Disorders, Co-occurring Mental and Substance Use Disorders, Medications for Opioid Use Disorder
Interventions
Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Little Rock, Arkansas
Completed Not applicable Interventional Accepts healthy volunteers

Transforming Opioid Prescribing in Primary Care

NCT01909076
Conditions
Chronic Pain, Opioid-Related Disorders
Interventions
Electronic decision support tools, Enhanced patient education materials, Nurse care management, Electronic Patient Registry, Academic detailing
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

Addressing the Health Concerns of VA Women With Sexual Trauma

NCT02957747
Conditions
Stress Disorders, Post-Traumatic, Intimate Partner Violence, Alcohol-Related Disorders
Interventions
SHE
Behavioral
Lead sponsor
VISN 17 Center of Excellence
Federal
Eligibility
18 Years to 65 Years · Female only
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Temple, Texas • Waco, Texas
Completed Not applicable Interventional Results available

Primary Care Treatment Integrating Motivation and Exposure

NCT03812146
Conditions
Stress Disorders, Post-Traumatic, Alcohol-Related Disorders
Interventions
PC-TIME, PC-TAU
Behavioral
Lead sponsor
Syracuse VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Buffalo, New York • Syracuse, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Behavioral Health for Caregivers and Children After Pediatric Injury

NCT06856057
Conditions
Quality of Life, PTSD, Depression Not Otherwise Specified, Child Externalizing Behavior
Interventions
Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
348 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
4
States / cities
Los Angeles, California • Lexington, Kentucky • Ann Arbor, Michigan + 1 more
Conditions
Substance Use Disorders, Posttraumatic Stress Disorder, Opioid Use Disorder, Violence, Sexual, Violence, Gender-Based, Violence, Domestic
Interventions
Screening/Referral and Prevention
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Greenville, South Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

PTSD Screening in Pregnant Black Women

NCT06522022
Conditions
Pregnancy Early, PTSD
Interventions
Culturally Responsive SBIRT for OB, Brief Screening for PTSD
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
804 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Atlanta, Georgia • Kansas City, Missouri
Conditions
Traumatic Brain Injury (TBI), Post Traumatic Stress Disorder (PTSD)
Interventions
Driving Behavior Interview, Fitness-to-Drive Screening Measure, Clinical Driving Assessment, Propensity for Angry Driving Scale, Community Integration Questionnaire, Satisfaction with Life Questionnaire, Driving simulator evaluation, Focus Group Discussion Interview Guide
Behavioral · Other · Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Conditions
Stress Disorder, Biofeedback
Interventions
The StressEraser, Breathe2Relax, Reminder text messages
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
6 Years to 11 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Written Exposure Therapy
Interventions
Written Exposure Therapy (WET)
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Recruiting Phase 2 Interventional Accepts healthy volunteers

Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV

NCT02560805
Conditions
Stress Disorders, Post-Traumatic
Interventions
Microneurography, Combat virtual reality video clip, Handgrip Exercise, Cold Pressor Test (CPT), Sodium Nitroprusside (SNP), Phenylephrine, Losartan, Atenolol, Transcutaneous Vagal Nerve Stimulation (tVNS), Sham Transcutaneous Vagal Nerve Stimulation (tVNS)
Procedure · Behavioral · Drug + 1 more
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Decatur, Georgia