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Showing 1–24 of 148 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Brief smoking cessation counseling Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Smoking Cessation CM for Veterans With or at Risk for Cancer

NCT06432985
View directory record Official record
Conditions
Tobacco Use Disorder, Substance Use Disorder
Interventions
Focus Group, Contingency Management, Behavioral Counseling (Cognitive Behavioral Therapy, CBT), TUD Treatment as Usual (TAU)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoke-free Home Intervention in Permanent Supportive Housing

NCT04855357
View directory record Official record
Conditions
Smoking Cessation, Second Hand Tobacco Smoke
Interventions
Resident counselling, Staff Training
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Phase 2 Interventional Results available

Proactive Outreach for Smoking Treatment

NCT04988477
View directory record Official record
Conditions
Smoking, Tobacco, Mental Illness
Interventions
Study 3: Chronic care management, Study 2: Pilot trial
Behavioral
Lead sponsor
Sandra Japuntich
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Effectiveness of Pharmacists in Implementing the SCRIPT Protocol

NCT02433860
View directory record Official record
Conditions
Pregnancy
Interventions
pharmacist nicotine cessation counseling using SCRIPT protocol
Behavioral
Lead sponsor
Providence Medical Research Center
Other
Eligibility
18 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Phase 4 Interventional Results available

A Comparative Effectiveness RCT of Optimized Cessation Treatments

NCT02301403
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine patch, in-person counseling and quitline counseling, Preparation Nicotine Mini-Lozenges, Combination NRT (nicotine patch + nicotine mini-lozenges), Intensive In-Person Cessation Counseling, Extended Maintenance Counseling Calls, Automated Adherence Calls
Drug · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
623 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prize Reinforcement for Smoking Cessation

NCT00865254
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Standard Treatment, Traditional Contingency Management, Early Enhanced Contingency Management
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
13 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 27, 2013 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional Results available

A Quit Smoking Study Using Smartphones

NCT02164383
View directory record Official record
Conditions
Smoking Cessation, Smoking, Nicotine Dependence
Interventions
Nicotine patch, Cessation Counseling, Mobile Games
Drug · Behavioral · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 2, 2019 · Synced Sep 28, 2026, 8:58 PM EDT
Terminated Not applicable Interventional

Project QUIT+: Adapting and Testing a Smoking Cessation Intervention for Transgender and Gender Expansive Individuals

NCT06654414
View directory record Official record
Conditions
Smoking Cessation, Depression, Anxiety, Nicotine Dependence, Gender Minority Stress
Interventions
PRIDE QUIT, Enhanced Treatment As Usual (ETAU)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Phase 4 Interventional

Smoking Study With Behavioral Therapy for Hypertensive Patients

NCT00879177
View directory record Official record
Conditions
Cigarette Smoking, Hypertension
Interventions
Varenicline, behavioral therapy
Drug · Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Sep 28, 2026, 8:58 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Integrating Financial Coaching and Smoking Cessation Coaching

NCT05154669
View directory record Official record
Conditions
Smoking
Interventions
Financial counseling, Nicotine Replacement Therapy Agent - Patches, Nicotine Replacement Therapy Agent - Lozenges, Nicotine Replacement Therapy Agent - Gum
Other · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
602 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional Results available

Contingency Management for Smoking in Substance Abusers

NCT00807742
View directory record Official record
Conditions
Substance Abuse
Interventions
Nicotine Replacement Treatment (NRT), Brief Advice, Contingency Management, Non-Contingent Reinforcement
Drug · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional

Smartphone-delivered Automated Video-assisted Smoking Treatment for People Living With HIV

NCT03082482
View directory record Official record
Conditions
Smoking Cessation
Interventions
Self-help materials, nicotine patch, Counseling, Smartphone-delivered automated treatment
Behavioral · Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Long-term Varenicline Treatment for Smoking Cessation

NCT00828113
View directory record Official record
Conditions
Smoking
Interventions
varenicline, Individual smoking cessation counseling
Drug · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Madison, Wisconsin • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional

Electronic Cigarettes as a Harm Reduction Strategy Among People Living With HIV/AIDS

NCT04218708
View directory record Official record
Conditions
Nicotine Addiction
Interventions
Nicotine patch and gum, Minnesota Nicotine Withdrawal Scale (MNWS), ASSIST (the Alcohol, Smoking and Substance Involvement Screening), Counseling, NIDA Standardized Research E-cigarettes (SREC)
Other · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Combining Varenicline and Bupropion for Smoking Cessation

NCT00943618
View directory record Official record
Conditions
Smoking Cessation
Interventions
Varenicline, Bupropion, Placebo, Counseling/Phone Calls
Drug · Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
25 Years to 70 Years
Enrollment
641 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

N-acetylcysteine for Tobacco Use Disorder

NCT02737358
View directory record Official record
Conditions
Nicotine Dependence, Smoking
Interventions
N-acetylcysteine (NAC), Placebo
Drug · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2020 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tobacco Dependence Treatment for Asian Americans

NCT01091363
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Standard, Deep Cultural
Behavioral
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Sep 28, 2026, 8:58 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

A Randomized Clinical Trial Assessing Smoking Cessation Interventions In Dental Clinic Smokers

NCT00591175
View directory record Official record
Conditions
Smoking Cessation
Interventions
Standard Care only, Dental Hygienist provided counseling + Brief Questionnaire, Dental Hygienist provided counseling with personalized risk communication + Brief Questionnaire
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
1,072 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strategies to Promote Cessation in Smokers Who Are Not Ready To Quit

NCT02905656
View directory record Official record
Conditions
Smoking Cessation
Interventions
Brief Advice, Motivational Interviewing, Rate Reduction, Pharmacological, MI+RR
Behavioral · Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
903 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Phase 4 Interventional Results available

Smoking Cessation in Hospitalized Smokers

NCT01289275
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Patches, Telephone Counseling, Brief Hospital Counseling
Drug · Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
1,270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
6
States / cities
Chula Vista, California • Davis, California • La Jolla, California + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional

Motivation and Nicotine Patch Treatment for Under-served Smokers

NCT01684995
View directory record Official record
Conditions
Smoking Cessation
Interventions
Brief physician advice, nicotine patch, Individually Tailored Behavioral Skills training
Behavioral · Drug
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Timeline
1996 – 1999
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 12, 2012 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Phase 4 Interventional

Motivation Project: Testing Intervention Components for the Smoker Who is Unwilling to Quit

NCT02354872
View directory record Official record
Conditions
Smoking, Motivation, Smoking Cessation
Interventions
Nicotine Mini-Lozenge, Behavioral Reduction Counseling, 5Rs Motivation Counseling, Behavioral Activation Counseling, No Treatment
Drug · Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
577 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Smoking Cessation Intervention in Enhancing Cancer Outreach in Low-Income Adult Smokers

NCT00948129
View directory record Official record
Conditions
Cigarette Smoker, Current Every Day Smoker
Interventions
Laboratory Biomarker Analysis, Smoking Cessation Intervention, Telephone-Based Intervention, Tobacco Cessation Counseling
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
626 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2023 · Synced Sep 28, 2026, 8:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrated Smoking Cessation Treatment for Low Income Community Corrections

NCT01257490
View directory record Official record
Conditions
Smoking Cessation
Interventions
counseling vs. advice
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 80 Years
Enrollment
689 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 28, 2026, 8:58 PM EDT