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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:22 AM EST

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Showing 73–96 of 98 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Brief stop-smoking intervention Clear all
Completed Not applicable Interventional

Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings

NCT05030272
View directory record Official record
Conditions
Tobacco Use Disorder, Mental Illness, Recurring Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, Persistent Depressive Disorder
Interventions
Quit on the Go App (formerly "Learn to Quit " App), Brief advice, Nicotine patch, Smartphone coaching, Nicotine gum, Nicotine Lozenges
Device · Behavioral · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Buffalo, New York • Durham, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 9, 2026 · Synced Nov 15, 2026, 6:22 AM EST
Completed No phase listed Observational

Tobacco Assessment and Intervention With Low-Income Persons Living With HIV-AIDS (PLWHA) in Community-Based AIDS Service Organizations

NCT01482923
View directory record Official record
Conditions
Tobacco Cessation, HIV, AIDS
Interventions
Treatment as usual, AIR (Aspirations, Inspiration, Respiration)
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Nov 15, 2026, 6:22 AM EST
Not listed Not applicable Interventional

Smoking Cessation Following Psychiatric Hospitalization

NCT02204956
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Sustained Care, Usual Care
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Nov 15, 2026, 6:22 AM EST
Completed Phase 4 Interventional Results available

A Text Messaging Program for Smokers in Primary Care

NCT03174158
View directory record Official record
Conditions
Smoking Cessation
Interventions
Mailed nicotine replacement therapy, Text messaging, Brief advice
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Nov 15, 2026, 6:22 AM EST
Terminated Phase 2 Interventional Results available

Pre to Postoperative Smoking Cessation

NCT02683161
View directory record Official record
Conditions
Cigarette Smoking, Obesity
Interventions
Varenicline, Contingency Management, Behavioral Counseling
Drug · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Nov 15, 2026, 6:22 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of Biomarkers in Children to Help Parents Quit Tobacco

NCT04832659
View directory record Official record
Conditions
Tobacco Dependence
Interventions
CEASE, CEASE + BIO
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
865 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Nov 15, 2026, 6:22 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implementation of Genomics in Substance Use Disorder Treatment

NCT04768114
View directory record Official record
Conditions
Tobacco Use Disorder, Smoking Cessation, Tobacco Use Cessation
Interventions
Genetically-Informed RiskProfile, Brief Cessation Advice
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 3, 2024 · Synced Nov 15, 2026, 6:22 AM EST
Completed Phase 4 Interventional Results available

The END Perioperative Smoking Pilot Study

NCT02482233
View directory record Official record
Conditions
Smoking, Nicotine Addiction, Surgery
Interventions
ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling, brief advice, brochure
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Nov 15, 2026, 6:22 AM EST
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Maintaining Nonsmoking: Older Smokers - 1

NCT00086385
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Nicotine polacrilex, Bupropion
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2015 · Synced Nov 15, 2026, 6:22 AM EST
Not listed Phase 3 Interventional

Motivating Smokers With Mobility Impairments to Quit Smoking

NCT01585610
View directory record Official record
Conditions
Smoking
Interventions
DVD Intervention, Standard Care Printed Materials
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
560 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 14, 2015 · Synced Nov 15, 2026, 6:22 AM EST
Active, not recruiting Not applicable Interventional

Comparing an Opt-out to an opt-in Approach for Smoking Cessation in VA Primary Care Clinics

NCT03477435
View directory record Official record
Conditions
Tobacco Use
Interventions
Staff training and academic detailing
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
1,365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Nov 15, 2026, 6:22 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Hospitalized Smokers

NCT01305928
View directory record Official record
Conditions
Hospitalized Smokers
Interventions
Warm Hand-off, Fax
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,054 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2016 · Synced Nov 15, 2026, 6:22 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Drug /Cue Interactions In Alcohol-Tobacco Comorbidity

NCT00816231
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Tobacco, Alcoholic Beverage, Placebo
Behavioral · Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
244 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Nov 15, 2026, 6:22 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

E-cigarette Switching Older Adults

NCT06534905
View directory record Official record
Conditions
Tobacco Use, Opioid Use Disorder, Tobacco-Related Disorders
Interventions
E-cigarette, Control/Standard Advice
Other · Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Nov 15, 2026, 6:22 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Tobacco Quit Line Re-enrollments for the Underserved

NCT01260597
View directory record Official record
Conditions
Smoking
Interventions
IVR intervention, IVR control
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
18 Years and older
Enrollment
2,985 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 11, 2015 · Synced Nov 15, 2026, 6:22 AM EST
Completed Phase 2 Interventional Results available

Targeted Interventions for Weight-Concerned Smokers

NCT00105482
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Naltrexone, Transdermal nicotine replacement, Behavioral counseling
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Nov 15, 2026, 6:22 AM EST
Completed Not applicable Interventional

Smoking Relapse-Prevention Intervention for Cancer Patients

NCT01630161
View directory record Official record
Conditions
Smoking Cessation
Interventions
Usual Care, Smoking Relapse Prevention for Cancer Patients (SRP-CaP)
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
441 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Nov 15, 2026, 6:22 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Impact of CONNECT in a Multilingual Population

NCT07111936
View directory record Official record
Conditions
Smoking Cessation, Smoking Cessation Counseling Ability and Practice, Smoking Cessation Counselling, Lung Cancer Screening
Interventions
CONNECT Intervention for multilingual populations, Saliva Sample, Interview
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years to 80 Years
Enrollment
439 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Nov 15, 2026, 6:22 AM EST
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility of Delivering VergeRx at FQHCs

NCT06161675
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
QuitAid, SmokefreeTXT, Nicotine Replacement Therapy Patch, Nicotine lozenge
Behavioral · Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Nov 15, 2026, 6:22 AM EST
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

CONNECTing to LungCare

NCT06213532
View directory record Official record
Conditions
Smoking Cessation, Cigarette Smoking-Related Carcinoma, Lung Carcinoma
Interventions
Smoking Cessation Intervention, Saliva Collection, Survey Administration
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 9, 2026 · Synced Nov 15, 2026, 6:22 AM EST
Completed Not applicable Interventional Results available

A Quit Smoking Study Using Smartphones

NCT02164383
View directory record Official record
Conditions
Smoking Cessation, Smoking, Nicotine Dependence
Interventions
Nicotine patch, Cessation Counseling, Mobile Games
Drug · Behavioral · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 3, 2019 · Synced Nov 15, 2026, 6:22 AM EST
Completed Phase 4 Interventional Results available

Engagement With an Adaptive Mobile Health Smoking Cessation Intervention

NCT04020718
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Brief telephone advice plus tailored text messages, Mailed nicotine replacement therapy, Proactive telephone coaching
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Nov 15, 2026, 6:22 AM EST
Completed Phase 2 Interventional Results available

Effect of Galantamine on Short-term Abstinence

NCT01669538
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Galantamine, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Nov 15, 2026, 6:22 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Chicago Community Health Study

NCT04460417
View directory record Official record
Conditions
Smoking
Interventions
Enhanced Care, TAU
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Nov 15, 2026, 6:22 AM EST