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Conditions: Insomnia
Interventions: Sleep Education Program, Mind-Body Bridging Program, Mindfulness Meditation Program; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 65 Years
Enrollment: 57 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Bipolar Disorder, Sleep Problems, Suicidal Thoughts
Interventions: Brief Sleep Intervention; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Insomnia Disorder, Cognitive Functioning
Interventions: CBTi: Stimulus Control Core, CBTi: Sleep Restriction Core, CBTi: Sleep Compression Core; Behavioral
Lead sponsor: Idaho State University; Other
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Pocatello, Idaho

Conditions: Breast Cancer
Interventions: Exercise Recall Patient Reported Outcomes, Health Behavior Questionnaire (HBQ)30 Patient Reported Outcomes, Functional Assessment of Cancer Therapy-General (FACT-G) Patient Reported Outcomes, Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) Patient Reported Outcomes, Patient Reported Outcomes PROMIS Cognitive Function (Short Form 8a), Patient Reported Outcomes Functional Assessment of Cancer-Gynecology Oncology Group-Neurotoxicity (FACT/GOG-NTX-12), Patient Reported Outcomes PROMIS, Patient Reported Outcomes FACT-Endocrine Symptoms, Patient Reported Outcomes Penn Arthralgia Aging Survey, Patient Reported Outcomes PRO-CTCAE (patient-reported CTCAE), p16 tumor suppressor gene; Behavioral · Diagnostic Test
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 21 Years and older · Female only
Enrollment: 253 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Sleep Disturbance, Fatigue, Inflammatory Bowel Disease
Interventions: Behavioral Counseling, bupropion-SR; Behavioral · Drug
Lead sponsor: Eva Szigethy; Other
Eligibility: 15 Years to 30 Years
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Complex Insomnia
Interventions: eszopiclone, Brief behavioral therapy for insomnia; Drug · Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Orthopedic Trauma, Sleep Quality
Interventions: Standard Postoperative Care, Zolpidem, Melatonin, Sleep Hygiene Education, Actigraph GT3X-BT Actigraph; Other · Drug · Dietary Supplement + 2 more
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Alcohol Use Disorder, Insomnia
Interventions: Daridorexant, Placebo, Brief Counseling, MEMS and Medication Accounting, Contingency Management for Medication Adherence; Drug · Behavioral · Device
Lead sponsor: Sterling McPherson; Other
Eligibility: 18 Years and older
Enrollment: 205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Menopause
Interventions: Cognitive Behavioral Therapy for Insomnia, Sleep Education, Sleep Restriction Therapy; Behavioral
Lead sponsor: Christopher Drake; Other
Eligibility: 45 Years to 65 Years · Female only
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
Interventions: Cognitive Behavioral Therapy; Behavioral
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 3
States / cities: San Antonio, Texas

Conditions: Insomnia, Depression, Suicidal Ideation
Interventions: Sleep Intervention I, Sleep Intervention II; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 2
States / cities: Palo Alto, California • Stanford, California

Conditions: Chronic Insomnia
Interventions: Brief behavioral treatment for insomnia, Healthy Eating Control; Behavioral
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 2
States / cities: Buffalo, New York

Conditions: Asthma, Sleep, Asthma in Children
Interventions: MAST - Managing Asthma & Sleep in Teens, ASMA - Asthma Self-Management for Adol, Information & Referral Control Group; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 13 Years to 17 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: New York, New York • Providence, Rhode Island

Conditions: Nocturia, Insomnia
Interventions: Integrated Behavioral Therapy Program, Health Education Program; Behavioral
Lead sponsor: Atlanta VA Medical Center; Federal
Eligibility: 60 Years and older
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 2
States / cities: Los Angeles, California • Atlanta, Georgia

Conditions: Moderate to Severe Insomnia
Interventions: Transcranial alternating current stimulator; Device
Lead sponsor: Nexalin Technology; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: TBI
Interventions: Sildenafil citrate, Functional Near Infared Spectroscopy, Hypercapnia Challenge; Drug · Device · Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obesity, Insufficient Sleep
Interventions: sleep extension intervention, contact control intervention; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 21 Years to 75 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Depression, Insomnia
Interventions: Cognitive Behavioral Therapy for insomnia and depression; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 12 Years to 20 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Berkeley, California • Portland, Oregon

Conditions: Insomnia, Alcohol Use, Marijuana Use
Interventions: Brief Behavioral Therapy for Insomnia (BBTI), Brief Alcohol Screening and Intervention for College Students (BASICS), Attention Control; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 29 Years
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Gastrointestinal Cancer
Interventions: My Sleep Our Sleep (MSOS) Program, Brief Behavioral Treatment for Insomnia (BBTI); Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 152 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Coral Gables, Florida • Pittsburgh, Pennsylvania

Conditions: Pain Related to Cancer, Cancer of Head and Neck
Interventions: Hypnosis, Mindfulness; Behavioral
Lead sponsor: VA Puget Sound Health Care System; Federal
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Sleep Disturbance, Insomnia
Interventions: Remote Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Insomnia, Cognition, Aging, HIV
Interventions: BBTI, BMT; Behavioral
Lead sponsor: University of Alabama, Tuscaloosa; Other
Eligibility: 50 Years to 99 Years
Enrollment: 214 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 2
States / cities: Birmingham, Alabama • Tuscaloosa, Alabama

Conditions: Insomnia, End Stage Renal Disease
Interventions: Cognitive Behavioral Therapy for Insomnia, Trazodone, Placebo; Behavioral · Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

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Sleep Management in Cancer Survivors

Brief Sleep Intervention for Bipolar Disorder

Assessing Modified CBTi in Adults With Insomnia Disorder

Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment

Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease

Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD

Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients

Daridorexant for People With Insomnia and Alcohol Use Disorder Study

Behavioral Treatment of Menopausal Insomnia; Sleep and Daytime Outcomes

Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings

A Brief Behavioral Sleep Intervention for Depression Among Military Veterans

Brief Behavioral Treatment for Insomnia in Cancer Survivors

Sleep Quality in High School Students With Asthma - II

Multi-center Trial to Improve Nocturia and Sleep in Older Adults

HALO Clarity™ Cranial Alternating Current Stimulation Therapy for Adults With Moderate-to-Severe Insomnia

Non-invasive Measurement of Cerebrovascular Reactivity After Traumatic Brain Injury

Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

Young Adult and Teen Sleep Study

Brief Interventions to Reduce Comorbid Alcohol and Cannabis Misuse and Sleep Impairment in Young Adults (Rest-Up RCT)

Dyadic Sleep Study

Hypnosis and Meditation for Cancer Pain

Brief Telehealth CBT-I Intervention in the Context of the COVID-19 Pandemic

The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV

Short and Long-Term Effectiveness of Existing Insomnia Therapies for Patients Undergoing Hemodialysis