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Showing 25–48 of 67 matching trials from the live ClinicalTrials.gov search.
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating the Bioavailability of Broccoli Extract Supplements

NCT07564674
Conditions
Diet, Healthy
Interventions
Avmacol Extra Strength with coating - 1 tablet, Avmacol chewable wafer - 2 tablets, Avmacol Extra Strength with coating - 2 tablets
Dietary Supplement
Lead sponsor
Oregon State University
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Corvallis, Oregon
Completed Not applicable Interventional Accepts healthy volunteers

Bioavailability of Phytonutrients From Novel Preparations of Broccoli

NCT03773497
Conditions
Healthy Volunteers
Interventions
Common Snack Combination, Cheesy Broccoli Snack, Cheesy Broccoli with Daikon Radish Snack, Uncooked Broccoli Snack
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
21 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Beltsville, Maryland
Conditions
Type 1 Diabetes
Interventions
NUTRI-Beta Counseling, Standard dietary counseling, Free weekly produce foods
Other · Dietary Supplement
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
6 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Hershey, Pennsylvania
Completed Phase 2 Interventional Results available

Sulforaphane to Reduce Symptoms of Schizophrenia

NCT02810964
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Sulforaphane Nutraceutical, Identical-appearing Placebo
Drug
Lead sponsor
Sheppard Pratt Health System
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Towson, Maryland
Conditions
Healthy Adult Volunteers
Interventions
Supplement A followed by Supplement B, Supplement B followed by Supplement A
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Blueberries in Older Adults

NCT05358210
Conditions
Blood Pressure, Orthostatic Hypotension, Vascular Diseases
Interventions
Blueberry Consumption, Dried Date Consumption
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
70 Years to 100 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Brookline, Massachusetts • Dedham, Massachusetts
Conditions
Smoking
Interventions
Broccoli sprout homogenate, Alfalfa sprout homogenate
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 40 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Phase 2 Interventional Results available

Sulforaphane-rich Broccoli Sprout Extract for Autism

NCT01474993
Conditions
Autism
Interventions
Sulforaphane-rich Broccoli Sprout Extract, Placebo
Drug
Lead sponsor
Andrew Zimmerman
Other
Eligibility
13 Years to 30 Years · Male only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Lexington, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Fermented Vegetables on Gut Microflora and Inflammation in Women

NCT03407794
Conditions
Inflammation, Women's Health, Gastrointestinal Microbiome
Interventions
Fermented vegetable, Non-fermented vegetable
Other
Lead sponsor
University of North Florida
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder

NCT05902754
Conditions
Alcohol Use Disorder
Interventions
Generally Recognized as Safe - Sulforaphane, Placebo
Dietary Supplement
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
50 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Diet, Healthy
Interventions
Standard Process Hemp Oil Complex
Dietary Supplement
Lead sponsor
Standard Process Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Kannapolis, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dietary Assessment Study Via Digital Images

NCT03267004
Conditions
Diet Habit
Interventions
Dietary Assessment of Meal A using images taken by Sony Smarteyeglass, Dietary Assessment of Meal B using Images taken by Sony Smarteyeglass
Device
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Knoxville, Tennessee
Completed Not applicable Interventional Results available

Effects of Whole Sprouts on Airway Allergic Inflammation

NCT01522703
Conditions
Allergic Rhinitis, Asthma, Allergy
Interventions
Broccoli Sprouts, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm, Occupational Malignant Neoplasm
Interventions
Acetaminophen, Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Placebo Administration, Questionnaire Administration, Training
Drug · Procedure · Dietary Supplement + 1 more
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol ES

NCT05408559
Conditions
Diastolic Dysfunction, Systolic Dysfunction, Diastolic Heart Failure
Interventions
Sulforaphane
Drug
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
60 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Lubbock, Texas
Conditions
Autism Spectrum Disorder, Autistic Disorder, Neurodevelopmental Disorder, Childhood Developmental Disorders, Pervasive
Interventions
Sulforaphane, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
13 Years to 30 Years · Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Carrboro, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Broccoli Sprouts Homogenate on SS RBC

NCT01715480
Conditions
Sickle Red Blood Cell, Fetal Hemoglobin, Oxidative Stress
Interventions
Broccosprouts® (Brassica Protection Products LLC) homogenate
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Nitrate-rich Fruit and Vegetable Supplement on Blood Pressure

NCT03486145
Conditions
High Blood Pressure, Flow Mediated Dilation
Interventions
fruit and vegetable juice supplement, Placebo
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 40 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Cardiovascular Diseases, Coronary Disease, Coronary Artery Disease, Heart Diseases, Myocardial Ischemia
Interventions
cardiac catheterization, coronary artery bypass graft surgery, percutaneous coronary intervention, Lifestyle, Medication
Procedure · Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
5,179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
109
States / cities
Birmingham, Alabama • Yuma, Arizona • Beverly Hills, California + 82 more
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Kale Consumption on Human Xenobiotic Metabolizing Enzymes

NCT03449849
Conditions
Healthy Volunteers
Interventions
Base Diet, Kale Treatment
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
21 Years to 75 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Beltsville, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Treatment Strategy to Enhance Nrf2 Signaling in Older Adults

NCT04848792
Conditions
Aging Problems
Interventions
Sulforaphane, Placebo capsules
Dietary Supplement
Lead sponsor
Northern Arizona University
Other
Eligibility
60 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Flagstaff, Arizona
Completed Phase 1 Interventional Accepts healthy volunteers

Glucobrassicin-Brussel Sprout Effect on D10 Phe Metabolism

NCT02999399
Conditions
Smoking
Interventions
Brussel Sprouts, Deuterated Phenanthrene
Other · Drug
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years to 99 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Obesity and Overweight, Breast Cancer Survivorship
Interventions
Broccoli microgreen (BMG)
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Autism, Autistic Disorder, Autism Spectrum Disorder, Autistic Behavior
Interventions
Sulforaphane, Placebo
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
13 Years to 30 Years · Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Piscataway, New Jersey