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Conditions: Methicillin-resistant Staphylococcus Aureus, Methicillin-Sensitive Staphylococcus Aureus Infection
Interventions: 4-day systematic oral hygiene, Standard of Care oral care; Procedure · Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Malignant Pleural Mesothelioma
Interventions: E-Nose testing, Research blood; Diagnostic Test
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 30 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Dental Caries
Interventions: Toothpaste & Telephone Support; Behavioral
Lead sponsor: Advantage Dental Services, LLC; Industry
Eligibility: 6 Months to 20 Years
Enrollment: 21,731 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Redmond, Oregon

Conditions: Healthy
Interventions: Listerine Experimental Mouthwash, Colgate Cavity Protection Toothpaste, Listerine Total Care Zero, Listerine Cool Mint Zero; Drug · Other
Lead sponsor: Johnson & Johnson Consumer Inc. (J&JCI); Industry
Eligibility: 18 Years and older
Enrollment: 163 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Bacteremia
Interventions: Effect of Amoxicillin on bacteremia following a single-tooth extraction; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 290 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Staphylococcal Skin Infections, Abscesses, Furunculosis, Staphylococcus Aureus, MRSA Infection
Interventions: 2% Mupirocin Ointment, 4% Chlorhexidine liquid soap, Hygiene protocol; Drug · Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 6 Months to 21 Years
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Type II Diabetes, Periodontal Disease
Interventions: Triclosan containing toothpaste, Non-triclosan containing toothpaste; Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 70 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Healthy
Interventions: Brush Only, Brush / Rinse (Jolly Rancher Prototype), Brush / Rinse (LISTERINE® Total Care Zero Alcohol); Other
Lead sponsor: Johnson & Johnson Consumer and Personal Products Worldwide; Industry
Eligibility: 6 Years to 11 Years
Enrollment: 161 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Dental Caries
Interventions: C16G2 Gel, Placebo; Drug · Other
Lead sponsor: Armata Pharmaceuticals, Inc.; Industry
Eligibility: 12 Years to 75 Years
Enrollment: 135 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 10
States / cities: Imperial Beach, California • Indianapolis, Indiana • Boston, Massachusetts + 6 more

Conditions: Ventilator Associated Pneumonia
Interventions: Toothbrushing only, Chlorhexidine only, Toothbrushing and Chlorhexidine; Procedure
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 547 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Dental Caries, Dry Mouth, Periodontal Diseases, Bleeding Gum
Interventions: EHR Changes, Medical Staff EHR Training, Clinician CSM theory-based didactic education and skills training, Standard ADA Oral Health Training; Behavioral
Lead sponsor: Case Western Reserve University; Other
Eligibility: 55 Years and older
Enrollment: 929 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Dental Caries
Interventions: C16G2 Varnish, Placebo Varnish; Drug
Lead sponsor: Armata Pharmaceuticals, Inc.; Industry
Eligibility: 12 Years to 75 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 3
States / cities: Kalispell, Montana • Bedford, Texas • Irving, Texas

Conditions: Pulmonary Lesions, Pulmonary Nodules, Pulmonary Mass
Interventions: Standard FB with fluoroscopy, R-EBUS with ultrathin bronchoscope; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 22 Years and older
Enrollment: 339 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 5
States / cities: Washington D.C., District of Columbia • Gainesville, Florida • Baltimore, Maryland + 2 more

Conditions: Esophagogastric Cancer
Interventions: Survey, Intra-oral camera, Optional Salvia sample; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 174 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: HPV, HPV - Anogenital Human Papilloma Virus Infection
Interventions: Mia by XytoTest, Rovers Cervex-Brush; Diagnostic Test
Lead sponsor: Mel Mont Medical; Industry
Eligibility: 25 Years to 65 Years · Female only
Enrollment: 260 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 11
States / cities: Phoenix, Arizona • Sherman Oaks, California • Lake Worth, Florida + 8 more

Conditions: Gingivitis, Plaque, Dental, Periodontal Diseases
Interventions: Cetylpyridinium Chloride (CPC) 0.09% + Xylitol chewing gum, Xylitol only chewing gum; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Depression, Suicide
Interventions: ketamin; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 50 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Oral Hygiene
Interventions: Experimental Dentifrice 1, Experimental Dentifrice 2, Reference Dentifrice; Drug
Lead sponsor: HALEON; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 280 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Melbourne, Florida

Conditions: Dental Plaque
Interventions: Fluoride, Triclosan/Fluoride; Drug
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 53 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: New York, New York

Conditions: Epiretinal Membrane, Vitreomacular Traction
Interventions: using ILM forceps alone, Breaking and peeling with end-grasping forceps; Procedure
Lead sponsor: Michael E. DeBakey VA Medical Center; Federal
Eligibility: 19 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Dentin Sensitivity, Oral Hygiene
Interventions: Test Dentifrice, Reference Dentifrice (Aquafresh Cavity Protection); Drug
Lead sponsor: HALEON; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Dental Disease, Behavioral Changes
Interventions: Personalized Digital Oral Health Coaching; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 80 Years
Enrollment: 230 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Petaluma, California • Santa Cruz, California

Conditions: Keratoconus
Interventions: Riboflavin-5-phosphate, Sham cross-linking; Drug
Lead sponsor: University at Buffalo; Other
Eligibility: 16 Years to 35 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Amherst, New York • Buffalo, New York

Conditions: Dental Plaque, Gingivitis
Interventions: Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste, Cetylpyridinium chloride mouthwash, Fluoride only mouthwash; Drug
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 179 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Cedar Knolls, New Jersey

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A Systematic Oral Care Program in Post-Mechanically Ventilated, Post-Intensive Care Patients

Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural Mesothelioma

Everybody Brush: A Community-wide Toothpaste Distribution Campaign

A Two-Week Study of an Anticavity Low pH Mouthwash

Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing

Staphylococcus Aureus Decolonization Study

Periodontal Treatment Response in Type II Diabetic Patients

Determination of the Oral Irritation Potential of a Fluoride Rinse in Children

Phase 2 Study to Evaluate the Microbiology and Safety of C16G2 Administered to Adult and Adolescent Dental Subjects

Strategies to Prevent Pneumonia (SToP Pneumonia)

Oral Health Intervention in Adult Primary Care

A Study to Evaluate the Safety and Microbiology of C16G2 Varnish Administered in Multiple Doses to Dental Subjects

Ultrathin Bronchoscope and Radial Endobronchial Ultrasound (R-EBUS) With Fluoroscopy Versus Standard Fiberoptic Bronchoscopy (FB) (P00029233 )

A Study of Tooth Erosion in People With Esophagogastric Cancer

Comparative Self-collection for Cervical Cancer Screening Pivotal Study

Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis

Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome

Clinical Study to Investigate the Tooth Stain Removal Efficacy of Two Experimental Toothpastes Compared to a Standard Toothpaste When Used Twice Daily for 8 Weeks

Clinical Study to Compare Dental Plaque Control

Comparison of Two Techniques for Epiretinal or Internal Limiting Membrane Peel

A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching

Personalized Digital Coaching for Oral Hygiene Adherence: Randomized Controlled Trial.

Treatment of Keratoconus Using Collagen Cross-Linking

Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)