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ClinicalTrials.gov public records Last synced Oct 5, 2026, 5:52 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Bupivacaine via epidural Clear all
Recruiting Phase 4 Interventional Accepts healthy volunteers

ED90 of Bupivacaine After Lidocaine Test Dose With DPE and EPL

NCT06146842
View directory record Official record
Conditions
Labor Pain
Interventions
Bupivacaine Hydrochloride
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 5, 2026, 5:52 PM EDT
Completed Phase 1 Interventional Results available

Epidural Neostigmine for Labor Pain

NCT00779467
View directory record Official record
Conditions
Labor Pain
Interventions
Neostigmine, Bupivacaine, fentanyl
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 5, 2026, 5:52 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Analgesic Techniques on Duration of Labor for Induction Patients

NCT01982851
View directory record Official record
Conditions
Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
Interventions
Epidural de novo, CSE
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 11, 2014 · Synced Oct 5, 2026, 5:52 PM EDT
Completed Not applicable Interventional

Comparing the Efficacy of Epidural and Quadratus Lumborum Analgesia After Open Nephrectomy Surgery

NCT03110081
View directory record Official record
Conditions
Open Nephrectomy Surgery
Interventions
Quadratus lumborum block, Epidural analgesia
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 5, 2026, 5:52 PM EDT
Completed Phase 3 Interventional

Effects of Additional Fentanyl to Epidural Bupivacaine for Post-Thoracotomy Pain in Neonates

NCT00286143
View directory record Official record
Conditions
Congenital Cystic Adenomatoid Malformation
Interventions
Fentanyl
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 6 Months
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2009 · Synced Oct 5, 2026, 5:52 PM EDT
Active, not recruiting Phase 3 Interventional

Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery

NCT03214510
View directory record Official record
Conditions
Liver and Intrahepatic Bile Duct Disorder
Interventions
Bupivacaine, Fentanyl, Hydromorphone Hydrochloride, Implanted Medical Device, Liposomal Bupivacaine, Questionnaire
Drug · Device · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 5, 2026, 5:52 PM EDT
Recruiting Phase 2 Interventional

Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

NCT06411795
View directory record Official record
Conditions
Duodenal Neoplasm, Pancreatic Neoplasm
Interventions
Bupivacaine, Hydromorphone, Iopamidol, Liposomal Bupivacaine, Medical Chart Review, Questionnaire Administration, Thoracic Epidural Analgesia, Ultrasound Imaging, X-Ray Imaging
Drug · Other · Procedure
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 5, 2026, 5:52 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Epidural Loading: High Volume, Low Concentration

NCT02803450
View directory record Official record
Conditions
Labor and Delivery
Interventions
Epidural needle, Catheter Administration, Standard of Care Epidural Administration
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 89 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Oct 5, 2026, 5:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty

NCT02121392
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee, Nerve Block
Interventions
Adductor Canal Nerve Block Catheter, Adductor Canal Nerve Block Sham Catheter, Bupivacaine
Device · Drug
Lead sponsor
University of Chicago
Other
Eligibility
Up to 85 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 5, 2026, 5:52 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients

NCT01982838
View directory record Official record
Conditions
Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
Interventions
Epidural de novo, CSE
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 11, 2014 · Synced Oct 5, 2026, 5:52 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Bupivacaine Induced Motor Blockade During the Second Stage of Labor

NCT01621230
View directory record Official record
Conditions
Pregnancy
Interventions
Epidural Bupivacaine plus fentanyl, Epidural fentanyl
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
16 Years to 44 Years · Female only
Enrollment
481 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Oct 5, 2026, 5:52 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Dexamethasone Administered Via the Epidural Catheter as an Adjunct in Patients Undergoing Cesarean Delivery

NCT03877549
View directory record Official record
Conditions
Post Operative Pain
Interventions
Dexamethasone
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 5, 2026, 5:52 PM EDT
Terminated Phase 2 Interventional Results available

Dose Finding Posterolateral Thoracotomy Study

NCT00807209
View directory record Official record
Conditions
Postoperative Pain
Interventions
Low Dose SKY0402, High Dose SKY0402, Placebo, Fentanyl via PCA, Bupivacaine via epidural
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
5
States / cities
Pasadena, California • Orlando, Florida • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated May 15, 2012 · Synced Oct 5, 2026, 5:52 PM EDT
Recruiting Phase 4 Interventional

Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release

NCT07840183
View directory record Official record
Conditions
Ventral Hernia, Ventral Hernia Repair, Postoperative Pain
Interventions
Bupivicaine, Fentanyl, Thoracic epidural analgesia, Hydromorphone, Acetaminophen, Ketorolac, magnesium sulfate, Tramadol, Gabapentin, Cyclobenzaprine, transversus abdominis plane block
Drug · Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 5, 2026, 5:52 PM EDT
Terminated Phase 4 Interventional Results available

Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery

NCT03115151
View directory record Official record
Conditions
Pain
Interventions
Bupivacaine, Hydromorphone, Fentanyl
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 5, 2026, 5:52 PM EDT
Terminated Not applicable Interventional

Epidural Technique: Does it Really Matter to the Patient?

NCT03539796
View directory record Official record
Conditions
Anesthesia
Interventions
Dural puncture epidurals (DPE), Traditional epidurals (EPI), Combined-spinal epidural technique (CSE)
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Oct 5, 2026, 5:52 PM EDT