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ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:26 PM EST

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Showing 25–48 of 138 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Bupivicaine Clear all

Conditions: Post-Mastectomy Chronic Pain Syndrome (Disorder)
Interventions: Cryoablation, Therapeutic Peripheral Nerve Block (tPNB) Injection; Procedure
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 4
States / cities: Atlanta, Georgia • Johns Creek, Georgia

Conditions: Hot Flashes, Hot Flushes, Vasomotor Symptoms
Interventions: Stellate Ganglion Block Injection with Bupivicaine, Saline injection; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 40 Years to 70 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Video Assisted Thoracoscopic Surgery, Pain, Postoperative, Pain, Acute
Interventions: US Guided Single Shot Paravertebral Block (0.2% ropivicaine infusion), US Guided Paravertebral Catheter (0.2% ropivicaine bolus), Thoracic Epidural (0.125% bupivicaine/hydromorphone); Drug
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 147 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Endodontic Disease, Post Operative Pain, Symptomatic Irreversible Pulpitis
Interventions: Local anesthetic; Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Hysterectomy
Interventions: Bupivacaine, Liposomal bupivacaine, Saline; Drug
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Pain, Postoperative, Opioid Use
Interventions: Bupivacaine; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Baltimore, Maryland • Columbia, Maryland

Conditions: Post Operative Pain
Interventions: 0.25% bupivicaine will be injected at the study port site prior to incision, Saline will be injected at the study port site prior to incision, Saline will be in injected into the port site prior to closure, 0.25% bupivicaine will be injected into the port site prior to closure; Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 21 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Pelvic Organ Prolapse
Interventions: pudendal block, no pudendal block; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Post Minimally Invasive Thorascopic Surgical Pain
Interventions: Bupivacaine and Dexamethasone, Placebo; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Post-operative Pain, Colon Cancer, Diverticulitis
Interventions: Bupivacaine, Bupivacaine liposome suspension; Drug
Lead sponsor: Des Moines University; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Des Moines, Iowa

Conditions: Laparoscopic Appendectomy
Interventions: Bupivacaine, Placebos; Drug
Lead sponsor: Metro Health, Michigan; Other
Eligibility: 18 Years and older
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Wyoming, Michigan

Conditions: Pain Following Thoracotomy Surgery
Interventions: Epidural, Intercostal Bupivicaine (Exparel); Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Amputation, Anesthesia, Local, Opioid Use
Interventions: Liposomal bupivacaine; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Post Operative Pain
Interventions: Group A-Paravertebral block, Group B- No block; Drug · Other
Lead sponsor: Loyola University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2021
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Postoperative Pain
Interventions: Bupivicaine Infusion; Drug
Lead sponsor: Chang, Steve S., M.D.; Individual
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Post Operative Pain, Appendicitis
Interventions: Pre Incisional Local Anesthetic, Pre-Incisional Saline, Post-Closure Local Anesthetic, Post-Closure Saline; Drug · Other
Lead sponsor: Valley Anesthesiology Consultants; Other
Eligibility: 9 Years to 17 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: ACL Surgery
Interventions: ACB within true AC with bupivacaine 0.5% 20cc, ACB proximal to true AC with bupivacaine 0.5% 20cc; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 75 Years
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Pain, Postoperative, Opioid Use
Interventions: Exparel, Saline infiltration; Drug · Other
Lead sponsor: Wright State University; Other
Eligibility: 18 Years to 45 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Dayton, Ohio

Conditions: Ventral Hernia, Ventral Hernia Repair, Postoperative Pain
Interventions: Bupivicaine, Fentanyl, Thoracic epidural analgesia, Hydromorphone, Acetaminophen, Ketorolac, magnesium sulfate, Tramadol, Gabapentin, Cyclobenzaprine, transversus abdominis plane block; Drug · Device · Procedure
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Postoperative Pain
Interventions: pre-operative carbohydrate drink, Acetaminophen, Gabapentin, Bupivacaine, Ambulation; Dietary Supplement · Drug · Other
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Trauma, Trauma Injury, Pain, Acute
Interventions: Bupivacaine Liposome Injection, Bupivacaine; Drug
Lead sponsor: Chadrick Evans; Other
Eligibility: 18 Years and older
Enrollment: 258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Peoria, Illinois

Conditions: Acute Pain, Surgery, Regional Anesthesia
Interventions: Epidural, TAP Block; Drug
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Retinal Detachment, Proliferative Vitreoretinopathy, Retinoschisis
Interventions: Triamcinolone, Bupivicaine Hydrochloride; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Labor Pain
Interventions: Combined Spinal-epidural, Continuous Lumbar epidural; Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 16 Years to 44 Years · Female only
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Dallas, Texas

Search by objective public record fields.

Cryoablation for Post Mastectomy Pain Syndrome

Stellate Ganglion Blockade in Post-Menopausal Women

Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.

Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment

Mixture of Liposomal Bupivacaine and Bupivacaine for TAP Block for Open Hysterectomy

Intra-operative Uterosacral Ligament Bupivacaine Injection During Minimally Invasive Hysterectomy

Study to Compare Reduction in Pain After Surgery With and Without Local Anesthesia During Laparoscopy

Use of Pre-Emptive Pudendal Nerve Block for Pelvic Reconstructive Surgery

The Effect of Dexamethasone on the Duration and Functionality of Bupivacaine Intercostal Nerve Blockade

The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery

A Study to Determine the Effectiveness of Utilizing Intraperitoneal Bupivacaine

Study of Exparel Versus Epidural for Pain Control After Thoracotomy

Use of Long-acting Bupivacaine In Lower Extremity Amputation

Paravertebral Block for Percutaneous Nephrolithotomy

Bupivicaine to Reduce Postoperative Pain in Laparoscopic Ventral Hernia Repair

Evaluation of Local Anesthetic at Incision Site

Optimal Location of Nerve Block to Minimize Perioperative Opioid Administration in ACL Surgery: Comparing True Adductor Canal to Proximal Block

Liposomal Bupivacaine After Cesarean Delivery

Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release

Enhanced Recovery After Surgery (ERAS) in Live Donor Kidney Transplant Recipients

Liposomal Bupivacaine Intercostal Nerve Block vs Thoracic Epidural for Regional Analgesia in Multiple Rib Fractures

Comparison of Epidural and TAP Block in Abdominal Surgery

Postoperative Pain Control Following Vitreoretinal Surgery

Pain Relief Effects on Length of Labor