- Conditions
- Tobacco-Use Disorder, Schizophrenia, Psychotic Disorders
- Interventions
- bupropion SR, Cognitive Behavioral Group Therapy, nicotine replacement therapy
- Drug · Behavioral
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 51 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1998 – 2004
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 33
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Smoking, Tobacco Use Disorder
- Interventions
- Bupropion SR & Varenicline
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 38 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Tobacco Dependence, Smoking
- Interventions
- Active bupropion + counseling, Active bupropion, No counseling, Placebo medication + counseling, Placebo medication, No counseling
- Drug
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 463 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2001 – 2003
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Methamphetamine Use Disorder
- Interventions
- bupropion SR
- Drug
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 2
- States / cities
- Omaha, Nebraska
- Conditions
- Depression
- Interventions
- Bupropion
- Drug
- Lead sponsor
- Uma Rao
- Other
- Eligibility
- 12 Years to 50 Years
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2014
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Tobacco Use Disorder, Smoking Cessation
- Interventions
- Bupropion, Varenicline, Placebo, Smoking Cessation Counseling
- Drug · Behavioral
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 646 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2019
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Smoking, Nicotine Dependence
- Interventions
- Naltrexone, Bupropion
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2005
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Smoking Cessation
- Interventions
- Bupropion
- Drug
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Kansas City, Missouri
- Conditions
- Smoking
- Interventions
- bupropion, placebo
- Drug · Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2007
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Tobacco Dependence
- Interventions
- bupropion + nicotine gum, Active bupropion-Placebo gum, Placebo bupropion-Placebo gum
- Drug
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 608 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2001 – 2002
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Smoking Cessation
- Interventions
- Nicotine patch, Varenicline Tartrate, Bupropion
- Drug
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 392 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Kansas City, Missouri
- Conditions
- Methamphetamine Dependence
- Interventions
- Bupropion, Placebo
- Drug · Other
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 12
- States / cities
- Los Angeles, California • San Diego, California • San Francisco, California + 9 more
- Conditions
- Marijuana Abuse, Substance-Related Disorders
- Interventions
- Bupropion
- Drug
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Nicotine Dependence
- Interventions
- Chantix, Zyban, Nicotine patches
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 65 Years · Male only
- Enrollment
- 376 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 4
- States / cities
- Charlotte, North Carolina • Durham, North Carolina • Raleigh, North Carolina + 1 more
- Conditions
- Nicotine Dependence
- Interventions
- Varenicline, Bupropion, Nicotine patches, Placebo varenicline, Placebo bupropion, Placebo patch
- Drug · Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 282 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 2
- States / cities
- Durham, North Carolina • Raleigh, North Carolina
- Conditions
- Pancreatitis, Chronic, Pancreatitis, Acute, Recurrent Acute Pancreatitis, Smoking (Tobacco) Addiction
- Interventions
- Standard Varenicline Dosing (1 mg BID), Bupropion 150 mg twice daily, Increased Varenicline Dosing (1mg TID)
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Head And Neck Cancer
- Interventions
- Placebo, Armodafinil, Minocycline, Bupropion
- Other · Drug
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Major Depressive Disorder, Treatment Resistant Depression
- Interventions
- AXS-05, Bupropion SR
- Drug
- Lead sponsor
- Axsome Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 312 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Cigarette Smoking, Marijuana Abuse
- Interventions
- bupropion, transdermal nicotine patch, Nicotine polacrilex, nicotine lozenge, counseling for marijuana and smoking cessation, mobile contingency management
- Drug · Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Smoking Cessation, Pregnancy
- Interventions
- Bupropion SR, placebo, smoking cessation counseling
- Drug · Behavioral
- Lead sponsor
- Watching Over Mothers & Babies Foundation
- Other
- Eligibility
- 18 Years to 45 Years · Female only
- Enrollment
- 135 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2001 – 2004
- U.S. locations
- 1
- States / cities
- Tucson, Arizona
- Conditions
- Tobacco Cessation
- Interventions
- Tailored behavioral counseling, Tobacco cessation pharmacotherapy
- Behavioral · Drug
- Lead sponsor
- Iowa City Veterans Affairs Medical Center
- Federal
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Pregnancy Related, Tobacco Use Disorder
- Interventions
- Bupropion SR, Smoking Cessation Counseling, Placebo
- Drug · Behavioral
- Lead sponsor
- The University of Texas Medical Branch, Galveston
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 1
- States / cities
- Galveston, Texas
- Conditions
- Major Depression, End Stage Renal Disease
- Interventions
- Fluoxetine, Bupropion
- Drug
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 30 Years to 70 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Adverse Effect of Drug Therapy Metabolism Medications (Diagnosis)
- Interventions
- Bupropion
- Drug
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana