Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.
Completed No phase listed Observational Accepts healthy volunteers Results available

Optimizing Prosthetic and Bicycle Fit for Veterans With Transtibial Amputations

NCT03828331
Conditions
Amputation
Interventions
Prosthetic/Bicycle Configuration
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Completed No phase listed Observational Accepts healthy volunteers Results available

Cadence and Intensity in Children and Adolescents (CADENCE-KIDS)

NCT01989104
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
6 Years to 20 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Parkinson Disease
Interventions
Digital music therapeutic, Active-Control
Device · Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
40 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Parkinson Disease
Interventions
Rapid Cadence Cycling on a Solo-Rider Spin Bicycle
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Parkinson Disease
Interventions
Dynamic high-cadence cycling
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
50 Years to 79 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Kent, Ohio
Conditions
Wellness, Self Compassion, Burnout, Anxiety, Depression
Interventions
App-based bundled mental fitness intervention, App-based wellness module collection
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Healthy Aging, Cognitive Benefits, Cardio Respiratory Fitness, Brain Activity
Interventions
High-Intensity Interval Training
Behavioral
Lead sponsor
Colby-Sawyer College
Other
Eligibility
55 Years to 79 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New London, New Hampshire
Conditions
Stress Urinary Incontinence
Interventions
Cadence Increase, Cadence Maintenance
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Parkinson Disease
Interventions
Postural control (weight shift) training, Steady state gait training
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
35 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Adaptive Self-Efficacy-Based AI Coaching for Cycling

NCT07318233
Conditions
Exercise Training, Exercise Behavior, Exercise Adherence Challenges, Motivation for Physical Activity, Motivational Enhancement
Interventions
Group 1: Self-efficacy-based AI coaching, Group 2: Static AI Affirmations
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Coral Gables, Florida
Completed Phase 3 Interventional Results available

A Study Designed to Evaluate Tear Production

NCT06544707
Conditions
Dry Eye Disease
Interventions
0.003% AR-15512 ophthalmic solution
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Newport Beach, California
Completed No phase listed Observational Accepts healthy volunteers

Cadence and Intensity Across the Adult Lifespan

NCT02650258
Conditions
Aging, Walking, Motor Activity, Activities of Daily Living
Interventions
treadmill walking
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
21 Years to 85 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
Multiple Sclerosis
Interventions
Forced Aerobic Exercise (FE), Voluntary Aerobic Exercise (VE)
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Cleveland, Ohio
Conditions
Healthy
Interventions
Cycling Cadence Modulation
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Coronary Artery Disease
Interventions
CADence
Diagnostic Test
Lead sponsor
AUM Cardiovascular, Inc.
Industry
Eligibility
22 Years and older
Enrollment
1,014 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
24
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 18 more
Conditions
Parkinson Disease
Interventions
Rhythmic Auditory Stimulation (RAS)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 89 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Lower Limb Amputation
Interventions
Comprehensive assessment of walking patterns and functional mobility, Comprehensive assessment of eye movements during walking, Questionnaire Assessments completed
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Type 2 Diabetes Mellitus, Walking
Interventions
Not listed
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
40 Years to 65 Years
Enrollment
20 participants
Timeline
2019
U.S. locations
1
States / cities
Amherst, Massachusetts
Conditions
Rheumatoid Arthritis, Degenerative Arthritis, Post Traumatic Arthritis
Interventions
Integra Cadence Total Ankle System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
9
States / cities
San Francisco, California • Sarasota, Florida • Buffalo, New York + 5 more
Conditions
Postmenopausal Disorder, Blood Pressure, Over Weight
Interventions
Basic Intervention, Enhanced Pedometry, Control Group
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
45 Years to 74 Years · Female only
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Lymphoma, Leukemia, Myeloma
Interventions
Resistance Training, Aerobic Exercise, Optional Aerobic Exercise Procedure, Optional In-Person Exercise Sessions
Behavioral · Radiation
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Heart Failure With Reduced Ejection Fraction
Interventions
HekaHeart platform medication management and remote monitoring
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Guilford, Connecticut • New Haven, Connecticut
Conditions
Chronic Pain
Interventions
Intraoperative Parameter Testing, Proprioception Testing During Stimulation, Gait Analysis During Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Parkinson Disease
Interventions
High-Intensity Aerobic Exercise (AE), Usual and Customary Care (UCC)
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Cleveland, Ohio • Salt Lake City, Utah