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ClinicalTrials.gov public records Last synced Nov 15, 2026, 4:19 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 459 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: CBT alone Clear all

Conditions: Bibliotherapy
Interventions: Doing What Matters in Times of Stress: An Illustrated Guide; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 141 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Bloomington, Indiana

Conditions: Alcohol Use Disorder, Alcohol Dependence, Drug Dependence
Interventions: DynamiCare Motivation Support Program, Untreated or Routine Care Control Group; Combination Product · Other
Lead sponsor: DynamiCare Health; Industry
Eligibility: 18 Years and older
Enrollment: 236 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Pain
Interventions: duloxetine, Web-based Cognitive Behavioral Therapy (CBT), Nurse-delivered Motivational Interviewing; Drug · Behavioral · Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 65 Years
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Tobacco Use Disorder
Interventions: Cognitive Behavioral Therapy (CBT), Cue-based treatment intervention; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Loneliness, Social Isolation, Rural Health
Interventions: Cognitive-Behavioral Therapy for Perceived Social Isolation, Health Education; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Cognitive Behavioral Therapy, Obsessive-Compulsive Disorder, Obsessive-Compulsive Disorder in Children, Obsessive-Compulsive Disorder in Adolescence
Interventions: Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 7 Years to 17 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Obstructive Sleep Apnea (OSA), Insomnia, Restless Leg Syndrome (RLS), Hypersomnia Type; Sleep Disorder, Shift Work Sleep Disorders
Interventions: Sleep VS; Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 1,260 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Fontana, California

Conditions: Suicide and Self-harm
Interventions: Dialectical Behavior Therapy, Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 12 Years to 18 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Stanford, California

Conditions: Major Depressive Disorder
Interventions: MoodGYM; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Anxiety Disorders
Interventions: Supporting Anxious Youth: Strategies for Caregivers; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 18 Years and older
Enrollment: 301 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC), Crohn Disease (CD), Anxiety
Interventions: Distraction VR, VR/AI CBT; Device
Lead sponsor: Brennan Spiegel; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Los Angeles, California • Chicago, Illinois

Conditions: Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Stroke
Interventions: Beating the Blues (BtB), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Usual Care; Behavioral · Drug · Other
Lead sponsor: Indiana University; Other
Eligibility: 50 Years and older
Enrollment: 216 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Autism Spectrum Disorder, Social Anxiety Disorder
Interventions: CBT, VR; Behavioral · Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Rumination Disorder
Interventions: CBT-RD; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 10 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Boston, Massachusetts • Philadelphia, Pennsylvania

Conditions: Sickle Cell Disease, Depression, Anxiety
Interventions: Computerized cognitive behavioral therapy; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Depression
Interventions: Cognitive behavior therapy with social cognitive training (CBT+SCT), CBT-only; Behavioral
Lead sponsor: Vanderbilt University; Other
Eligibility: 12 Years to 17 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Nashville, Tennessee

Conditions: CBT, LGBTQ
Interventions: LGBTQ-Affirmative CBT Training: Materials Only, LGBTQ-Affirmative CBT Training: Direct Training, LGBTQ-Affirmative CBT Training: Local Supervision; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 15 Years and older
Enrollment: 1,379 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Alcohol Dependence
Interventions: Mindfulness Based Relapse Prevention for Alcohol Dependence, "Wait-list" control; Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Obsessive-Compulsive Disorder
Interventions: Serotonin reuptake inhibitors management, Cognitive behavioral therapy by a psychologist, Instructional cognitive behavioral therapy by a psychiatrist; Drug · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 7 Years to 17 Years
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 3
States / cities: Durham, North Carolina • Philadelphia, Pennsylvania • Providence, Rhode Island

Conditions: Low Back Pain
Interventions: Physical Activity, Cognitive Behavioral Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 65 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smokers
Interventions: D-cycloserine, Placebo; Drug
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cancer, Insomnia
Interventions: CBT-I; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Nicotine Addiction, Panic Attack
Interventions: d-cycloserine, Pill Placebo, Nicotine replacement therapy, Panic and Smoking Reduction Treatment; Drug · Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Social Isolation, Suicidal Ideation
Interventions: Brief Cognitive Therapy, Social Prescribing, Enhanced Usual Care; Behavioral · Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Brighton, Michigan • Canton, Michigan

Search by objective public record fields.

Guided Self-help for Common Mental Disorders

Tech-Enabled CM for AUD at Scale

Pain Response Evaluation of a Combined Intervention to Cope Effectively

Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily

Fostering Agricultural Relationships and Meaning - Thriving on Kinship

CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD

Validating the Use of a Subjectively Reported Sleep Vital Sign

Combined Dialectical Behavior Therapy and Digital Cognitive Behavioral Therapy for Insomnia for Adolescents at High Risk for Suicide

Effectiveness and Acceptability of MoodGYM in Treating Depressive Symptoms in Chinese Americans

Parent Key Opinion Leaders to Increase Demand of Effective Treatments for Youth Anxiety

VR Therapies for IBD

eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients

Application of Virtual Reality Technology to Treatment of Social Anxiety

A Pilot Study of Cognitive-Behavioral Therapy for Rumination Disorder (CBT-RD)

Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications

CBT Enhanced With Social Cognitive Training

SGM Evidenced-Based Mental Healthcare Implementation

Mindfulness Meditation for Health

Treatment of Obsessive Compulsive Disorder in Children

Physical Activity for Older Adults Chronic Low Back Pain

D-Cycloserine Enhancement of Exposure-Based CBT for Smoking Cessation (DCSSmoking)

Improving Sleep in Cancer Patients: A Feasibility Trial

Enhancing Panic and Smoking Reduction Treatment With D-Cycloserine

Social Prescribing and Relationship Cognitive Strategies (SPARCS)