Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 6, 2026, 7:21 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 561 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: CBT for depression Clear all

Conditions: Immunodeficiency Virus, Human, Depressive Symptoms
Interventions: Cognitive Behavioral Therapy for Adherence and Depression; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 161 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 2
States / cities: Miami, Florida • Boston, Massachusetts

Conditions: Cognitive Impairment, Long COVID
Interventions: Digital cognitive behavioral intervention-RxWell, Amphetamine-Dextroamphetamine; Behavioral · Drug
Lead sponsor: Eva Szigethy; Other
Eligibility: 21 Years to 65 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Insomnia, Primary, Major Depressive Disorder, Rumination
Interventions: digital Cognitive Behavioral Therapy for Insomnia, face-to-face Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education Control; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Enrollment: 1,237 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Novi, Michigan

Conditions: Depression, Anxiety, Transition
Interventions: Adapted Teens Achieving Mastery over Stress (TEAMS) Treatment, Adapted Teens Achieving Mastery over Stress (TEAMS) Prevention, Adapted Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT), Strengthening Families, Virtual psycho-educational discussion groups for caregivers and participants, Maternal Child Health Bureau (MCHB) Care Coordination; Behavioral · Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 13 Years to 20 Years
Enrollment: 780 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Depressive Disorders, Anxiety Disorders, Pulmonary Disease, Chronic Obstructive
Interventions: Cognitive Behavioral Therapy; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 222 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Depression, Anxiety Disorders
Interventions: SilverCloud; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Major Depressive Disorder (MDD)
Interventions: Cognitive therapy for depression; Behavioral
Lead sponsor: University of California, Berkeley; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Acute Coronary Syndrome, Depressive Symptoms
Interventions: Cognitive Behavioral Therapy (CBT), Antidepressant Medication, Standard Care, Depressive symptom screener, No intervention; Other · Drug
Lead sponsor: Columbia University; Other
Eligibility: 21 Years and older
Enrollment: 1,501 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 4
States / cities: Bloomington, Minnesota • New York, New York • Henderson, North Carolina + 1 more

Conditions: Type 1 Diabetes Mellitus, Depressive Symptoms
Interventions: CATCH-IT; Behavioral
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 13 Years to 17 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Depression
Interventions: Cognitive factors, Behavioral factors, Increase engagement of pleasant events; Behavioral
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Chronic Kidney Disease Requiring Hemodialysis
Interventions: Technology Assisted Stepped Collaborative Care, Usual Care Arm; Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 424 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 2
States / cities: Albuquerque, New Mexico • Pittsburgh, Pennsylvania

Conditions: Adolescent Depression, Depression
Interventions: Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 14 Years to 18 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Cancer
Interventions: Acceptance and Commitment Therapy, Questionnaires; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Anxiety, Anxiety Depression, Worry, Depression, Rumination - Thoughts
Interventions: Be Specific, Be Kind, Be Present, Break Habit, Psychoeducation; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Imperial, California

Conditions: Depression
Interventions: Usual Standard of Care, Cognitive Behavioral Therapy Condition (CBT); Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Suicide, Attempted, Suicide, Ideation, Depression, Substance Abuse
Interventions: CBT-RP (relapse prevention) + Enhanced TAU, Enhanced TAU Alone; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 13 Years to 19 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Bipolar Disorder
Interventions: Mindfulness-Based Cognitive Behavioral Therapy or Supportive Psychotherapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Type 1 Diabetes
Interventions: Cognitive behavioral therapy for adherence and depression; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Hypertension
Interventions: Mindfulness-Based Stress Reduction (MBSR; CALM-Chicago Study); Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Anxiety, Depression, Emotional Disorder, Autism
Interventions: Transdiagnostic cognitive behavioral therapy (CBT), Treatment as usual; Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 10 Years to 17 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Substance Use Disorders, Depression, Anxiety, Emotional Disorder, Suicidal Ideation, Suicidal and Self-injurious Behavior
Interventions: Unified Protocol (UP), Treatment as Usual (TAU); Behavioral · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 26 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stress Disorders, Post-Traumatic
Interventions: Cognitive behavioral therapy (CBT), Educational session and treatment as usual; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 2
States / cities: New York, New York • Queens, New York

Conditions: HIV Infections, Depression, Substance-Related Disorders
Interventions: Cognitive Behavioral Therapy, Psychopharmacology; Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 175 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2003
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Depression
Interventions: Cognitive behavior therapy (CBT), Supportive/expressive (S/E) therapy, Bibliotherapy; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 14 Years to 18 Years
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Austin, Texas

Search by objective public record fields.

Effectiveness of Nurse-delivered Care for Adherence/Mood in HIV in South Africa

Addressing Cognitive Fog in Long-COVID-19 Patients

Sleep To Reduce Incident Depression Effectively

BEhavioral Health Stratified Treatment (BEST) Study for Youth With Intellectual and/or Developmental Disabilities (IDD)

A Cognitive-Behavioral Intervention for Depression and Anxiety in COPD

Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II

Improving Depression Outcome by Enhancing Memory for Cognitive Therapy

Comparison of Depression Identification After Acute Coronary Syndrome: Quality of Life and Cost Outcomes

Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms in Adolescents With Type 1 Diabetes Mellitus

Brief Inpatient Psychotherapy for Depression

Technology Assisted Collaborative Care Intervention to Improve Patient-centered Outcomes in Dialysis Patients

Predictors of Response to Treatment for Depression

COMPASS: A Group ACT Program for Cancer Patients Treated at UCSF

Calming Minds Study

Brief CBT for the Treatment of Depression During Inpatient Hospitalization

Relapse Prevention for Suicidal Dually Diagnosed Youths

Mindfulness-Based Cognitive Behavior Therapy for Bipolar Disorder

Cognitive Behavioral Therapy (CBT) for Adherence and Depression in Type 1 Diabetes

Community-based Approach to Lowering Stress Through Mindfulness

Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents

Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders

Safety and Efficacy of Cognitive Behavior Therapy for People With Post-traumatic Stress and Cardiovascular Illness

Cognitive Behavioral Therapy Combined With Antidepressants to Reduce HIV Risk and Drug Relapse Among Depressed Intravenous Drug Users

Depression Prevention Program for Adolescents