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Showing 1–24 of 557 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: CBT for depression Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations

NCT01093053
View directory record Official record
Conditions
Stress Disorders, Post Traumatic, Brain Injuries, Depressive Disorder, Anxiety Disorders, Anger
Interventions
Mind-Body Skills Groups, Standard Treatment
Behavioral · Other
Lead sponsor
The Center for Mind-Body Medicine
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 28, 2014 · Synced Sep 19, 2026, 9:03 AM EDT
Recruiting Not applicable Interventional

Amplification of Positivity for Alcohol Use

NCT06030154
View directory record Official record
Conditions
Alcohol Use Disorder, Anxiety, Depression
Interventions
Cognitive Behavioral Therapy, Amplification of Positivity Therapy, Surveys and Interviews
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Neural Circuit Biomarkers of Major Depression Response to CCBT

NCT03096886
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Depressive Disorder, Depression, Unipolar
Interventions
Computer-Augmented Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional Results available

IMPAACT 2002: Cognitive Behavioral Therapy and Medication Management for Treatment of Depression in US Youth With HIV

NCT02939131
View directory record Official record
Conditions
HIV, Depression
Interventions
Health and Wellness Combined Cognitive Behavioral Therapy and a Medication Management Algorithm, Enhanced Standard of Care
Behavioral
Lead sponsor
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Network
Eligibility
12 Years to 24 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
13
States / cities
Alhambra, California • La Jolla, California • Los Angeles, California + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Sep 19, 2026, 9:03 AM EDT
Terminated Not applicable Interventional

Project QUIT+: Adapting and Testing a Smoking Cessation Intervention for Transgender and Gender Expansive Individuals

NCT06654414
View directory record Official record
Conditions
Smoking Cessation, Depression, Anxiety, Nicotine Dependence, Gender Minority Stress
Interventions
PRIDE QUIT, Enhanced Treatment As Usual (ETAU)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Phase 3 Interventional

Optimal Treatment Strategies for Sexually Abused Children

NCT00073684
View directory record Official record
Conditions
Child Abuse, Sexual
Interventions
Trauma focused cognitive behavioral therapy (TF-CBT), Brief abuse-focused treatment, Brief coping skills treatment, Extended abuse-focused treatment, Extended coping skills treatment
Behavioral
Lead sponsor
Rowan University
Other
Eligibility
4 Years to 11 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Stratford, New Jersey
Source: ClinicalTrials.gov public record
Updated May 7, 2014 · Synced Sep 19, 2026, 9:03 AM EDT
Completed No phase listed Observational

COMPASS: A Group ACT Program for Cancer Patients Treated at UCSF

NCT04636346
View directory record Official record
Conditions
Cancer
Interventions
Acceptance and Commitment Therapy, Questionnaires
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional Results available

Internet-based CBT After Stroke Pilot

NCT03615079
View directory record Official record
Conditions
Stroke, Depression
Interventions
Cognitive behavioral therapy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 10, 2021 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Improving Depression Via E-Health Access (IDEA) Study

NCT04689568
View directory record Official record
Conditions
Depression
Interventions
Moodkit, Moodgym, University of Michigan Depression Center Toolkit
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Sep 19, 2026, 9:03 AM EDT
Recruiting Not applicable Interventional

Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults

NCT06060860
View directory record Official record
Conditions
Autism Spectrum Disorder, Depression, Anxiety
Interventions
Cognitive-Behavioral Therapy (CBT), Mindfulness-Based Cognitive Therapy (MBCT)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mood and Diabetes Empowerment & Improvement Training

NCT02010684
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Empowerment and CBT Classes
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 31, 2015 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional

The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions

NCT04245423
View directory record Official record
Conditions
Opioid-use Disorder, Mental Health Conditions
Interventions
Collaborative Care for Opioid Use Disorders and Mental Health Conditions, Augmented Usual Care, Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
567 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Phase 4 Interventional Results available

DECIFER: Depression and Citalopram In First Episode Recovery

NCT01041274
View directory record Official record
Conditions
Schizophrenia, Schizophreniform Disorder
Interventions
Citalopram, Placebo, Psychoeducation, Cognitive Behavioral Therapy (CBT), Functional Magnetic Resonance Imaging (fMRI)
Drug · Behavioral · Radiation
Lead sponsor
NYU Langone Health
Other
Eligibility
16 Years to 40 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors

NCT01929720
View directory record Official record
Conditions
Anxiety Disorder, Worry, Uncertainty, Sleep Disorders, Insomnia, Fatigue, Pain, Depression, Cognitive-behavioral Therapy, Psychological Intervention, Esophageal Cancer, Pancreatic Cancer, Leukemia, Lung Cancer, Multiple Myeloma, Ovarian Neoplasm, Stage III or IV Cervical or Uterine Cancer, Stage IIIB, IIIC, or IV Breast Cancer, Glioblastoma Multiforme, Relapsed Lymphoma, Stage III or IV Colorectal Cancer, Stage IIIC or IV Melanoma
Interventions
Cognitive-behavioral therapy for worry, uncertainty & insomnia
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

FASTLANE II: Reducing Sex, Drug, and Mental Health Risk

NCT04109014
View directory record Official record
Conditions
Methamphetamine Abuse, HIV/AIDS, Depression, Sex, Unsafe
Interventions
FASTLANE II
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2022 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy

NCT03691792
View directory record Official record
Conditions
Seasonal Affective Disorder
Interventions
Cognitive-Behavioral Therapy (CBT-SAD), Light Therapy
Behavioral · Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Sep 19, 2026, 9:03 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The DC Mother-Infant Behavioral Wellness Program

NCT05345834
View directory record Official record
Conditions
Perinatal Depression, Perinatal Anxiety, Prenatal Stress
Interventions
Patient Navigation, Adapted Cognitive-Behavioral Therapy
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 19, 2026, 9:03 AM EDT
Active, not recruiting Not applicable Interventional

Matching Adults to Treatments for Chronic Pain (MATCH) Study

NCT05699252
View directory record Official record
Conditions
Chronic Pain
Interventions
Cognitive Behavioral Therapy (CBT), Hypnotic Cognitive Therapy (HYP-CT), Mindfulness-Based Cognitive Therapy (MBCT)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Seattle, Washington • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Microcurrent Neurofeedback as an Adjunct to Standard Care for Substance Use Disorders

NCT07737652
View directory record Official record
Conditions
Depression, Anxiety, Substance Use Disorder (SUD), Post Traumatic Stress Disorder
Interventions
Microcurrent Neurofeedback (MCN), Standard Care for Substance Use Disorder
Device · Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II

NCT05555875
View directory record Official record
Conditions
Depression, Anxiety Disorders
Interventions
SilverCloud
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Combined Interventions for Treating Depression and Chronic Back Pain

NCT00158275
View directory record Official record
Conditions
Back Pain, Depression
Interventions
Cognitive behavioral therapy, Antidepressants, Problem solving therapy
Behavioral · Drug
Lead sponsor
Kaiser Permanente
Other
Eligibility
25 Years to 74 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 19, 2026, 9:03 AM EDT
Recruiting Not applicable Interventional

Valuation in Depressed Mood, Anhedonia, and Anxiety

NCT05384158
View directory record Official record
Conditions
Neurobehavioral Components of Reward and Loss Valuation
Interventions
cognitive behavioral therapy, valuation with instruction, valuation without instruction
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
25 Years to 50 Years
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional

Reducing Residual Depressive Symptoms With Web-based Mindful Mood Balance

NCT02190968
View directory record Official record
Conditions
Major Depressive Disorder, Recurrent, in Remission, Depressive Symptoms
Interventions
Usual Depression Care, Mindful Mood Balance
Behavioral
Lead sponsor
University of Toronto
Other
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 27, 2019 · Synced Sep 19, 2026, 9:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Thrive, a Computerized Cognitive Behavior Therapy Program to Treat Depression

NCT03244878
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Thrive
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years and older
Enrollment
464 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Sep 19, 2026, 9:03 AM EDT