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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: CBT-I Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

The Effects of Modafinil on Waking Function and on Sleep in Individuals With Primary Insomnia

NCT00124384
View directory record Official record
Conditions
Primary Insomnia
Interventions
CBT-I, modafinil
Behavioral · Drug
Lead sponsor
University of Rochester
Other
Eligibility
25 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2008 · Synced Sep 24, 2026, 1:56 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adaptation and Initial Evaluation of Transdiagnostic CBT for Anxious and Depressed Smokers

NCT03920137
View directory record Official record
Conditions
Smoking Cessation
Interventions
UP-ST Therapy, Standard Therapy, Nicotine Patch
Behavioral · Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional

A Trial of Parent-coached Exposure Therapy for Children With Anxiety Disorders and OCD

NCT05777161
View directory record Official record
Conditions
Anxiety Disorders, Obsessive-Compulsive Disorder
Interventions
Parent Coached Exposure Therapy - Individualized, Cognitive Behavior Therapy, Parent Coached Exposure Therapy - Group (removed from study)
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
7 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional

Mobile Intervention to Improve Functional Health and Community Engagement of Post-9/11 Veterans With Chronic Insomnia

NCT03305354
View directory record Official record
Conditions
Chronic Insomnia
Interventions
CBTI app intervention, Physical Activity intervention
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
21 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 24, 2026, 1:56 PM EDT
Recruiting Not applicable Interventional

Artificial Intelligence-Powered Support For Quality Of Life Improvement In Participants With Cancer

NCT07167056
View directory record Official record
Conditions
Cancer
Interventions
Standard of Care Psychotherapy, WYSA App
Behavioral
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Recruiting Not applicable Interventional

CBT-I in Older African American Adults

NCT06791356
View directory record Official record
Conditions
Older Adults (65 Years and Older)
Interventions
Cognitive-behavioral therapy for insomnia, Sleep hygiene education
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional

Comparative Effectiveness Feasibility Trial for Insomnia Among Breast Cancer Survivors

NCT03328169
View directory record Official record
Conditions
Breast Cancer Female, Insomnia
Interventions
Mindfulness-Based Therapy, Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 24, 2026, 1:56 PM EDT
Active, not recruiting Not applicable Interventional

The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients

NCT05226078
View directory record Official record
Conditions
Chronic Insomnia, Cancer-related Problem/Condition, Cancer-Related Syndrome
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
25 Years to 85 Years · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional Results available

Research on Expecting Moms and Sleep Therapy

NCT02805998
View directory record Official record
Conditions
Insomnia
Interventions
Web-based CBT-I, Treatment as Usual
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced Sep 24, 2026, 1:56 PM EDT
Active, not recruiting Not applicable Interventional

The Study in Outpatient Medicine Using Nudges to Improve Sleep

NCT06640023
View directory record Official record
Conditions
Inappropriate Prescribing
Interventions
Z-drug Default Quantity, Redirection + Accountable Justification
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers

NCT03012425
View directory record Official record
Conditions
Insomnia, Related Distress Among Cancer Caregivers
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Acupuncture, questionnaires, Diurnal Cortisol
Behavioral · Procedure · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
3
States / cities
Irvine, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2021 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Phase 2 Interventional

Fatigue Interventions in Cancer (Exercise Intervention)

NCT03421782
View directory record Official record
Conditions
Sedentary Lifestyle, Stage III Prostate Cancer AJCC v7, Stage IV Prostate Cancer AJCC v7
Interventions
Cognitive Behavior Therapy, Exercise Intervention
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
Not listed
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional Results available

mHealth for Breast Cancer Survivors With Insomnia

NCT05233800
View directory record Official record
Conditions
Breast Cancer Survivor, Insomnia
Interventions
Faster Asleep Smart Speaker Program, Faster Asleep Website
Behavioral
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional Results available

Treatment of Insomnia Secondary to Chronic Pain

NCT00127790
View directory record Official record
Conditions
Insomnia, Pain
Interventions
CBT for Insomnia (CBT-I), CBT for Pain (CBT-P)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
35 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2012 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional Results available

RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts

NCT03603717
View directory record Official record
Conditions
Insomnia, Suicidal Ideation
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Buffalo, New York • Canandaigua, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2024 · Synced Sep 24, 2026, 1:56 PM EDT
Recruiting Not applicable Interventional

Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety: R33 Phase

NCT07818876
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Cognitive Bias Modification for Interpretations (CBM-I), Cognitive Restructuring (CR)
Other
Lead sponsor
University of Denver
Other
Eligibility
10 Years to 17 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Phase 3 Interventional Results available

Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery

NCT00324805
View directory record Official record
Conditions
Stage IB Lung Non-Small Cell Carcinoma AJCC v7, Stage IIA Lung Non-Small Cell Carcinoma AJCC v7, Stage IIB Lung Non-Small Cell Carcinoma AJCC v7, Stage IIIA Lung Non-Small Cell Cancer AJCC v7
Interventions
Bevacizumab, Cisplatin, Docetaxel, Gemcitabine Hydrochloride, Laboratory Biomarker Analysis, Pemetrexed Disodium, Questionnaire Administration, Vinorelbine Tartrate
Biological · Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
1,501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2025
U.S. locations
1139
States / cities
Anniston, Alabama • Huntsville, Alabama • Mobile, Alabama + 712 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Active, not recruiting Not applicable Interventional

Radiation Therapy in Treating Patients With Recurrent Brain Tumors Who Have Undergone Previous Radiation Therapy

NCT02698254
View directory record Official record
Conditions
Recurrent Brain Neoplasm
Interventions
Bevacizumab, Quality-of-Life Assessment, Radiation Therapy
Biological · Other · Radiation
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional Results available

Preventing Persistent Post-Surgical Pain and Dysfunction

NCT03965897
View directory record Official record
Conditions
Pain, Function, Anxiety, Depression, Arthroplasty, Replacement, Knee, Veterans
Interventions
Acceptance and Commitment Therapy (ACT), Attention Control (AC)
Behavioral · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional

Chronic Insomnia and CSF Markers of Dementia - Effects of Treatment

NCT04073992
View directory record Official record
Conditions
Insomnia Chronic
Interventions
cognitive behavioral treatment of insomnia
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 50 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 16, 2023 · Synced Sep 24, 2026, 1:56 PM EDT
Terminated Not applicable Interventional

Brief Versus Standard Cognitive Behavioral Therapy for Insomnia in Veterans

NCT05724498
View directory record Official record
Conditions
Insomnia
Interventions
Brief CBT-I, Standard CBT-I
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
San Diego, California • Canandaigua, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional

Treatment for Depression Among HIV-Infected Youth

NCT01049789
View directory record Official record
Conditions
HIV, Depression, HIV Infections
Interventions
COMB - Combination Cognitive Behavioral Therapy and Medication Management, TAU - Treatment as Usual
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 24 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
4
States / cities
Tampa, Florida • The Bronx, New York • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Sep 24, 2026, 1:56 PM EDT
Active, not recruiting Not applicable Interventional

Treatments in Women Veterans With Insomnia and PTSD

NCT05683132
View directory record Official record
Conditions
Insomnia, PTSD, Women Veterans
Interventions
Trauma-Informed CBT-I, PTSD Psychoeducation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 24, 2026, 1:56 PM EDT
Completed Not applicable Interventional

Subjective Sleep Quality of Patients With Chronic Insomnia

NCT06550388
View directory record Official record
Conditions
Insomnia Chronic
Interventions
Nutritional Education, Physical Activity
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 24, 2026, 1:56 PM EDT