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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: CBT4CBT program Clear all
Completed Early Phase 1 Interventional Results available

Galantamine and CBT4CBT Pilot to Prevent Relapse.

NCT03547622
View directory record Official record
Conditions
Methadone or Buprenorphine Detoxoxification
Interventions
MAT taper with galantamine, MAT taper with placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Phase 1 Interventional

Computer-Based Training in Cognitive Behavior Therapy (CBT4CBT)

NCT01406899
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Computer Based Treatment
Behavioral
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Newington, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 22, 2014 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional

Preventing Premature Death in Patients With Serious Opioid-related Infection

NCT03999450
View directory record Official record
Conditions
Opioid Use
Interventions
brief motivational intervention (BMI), cognitive behavioral therapy
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional

Computer Based Training in CBT in Primary Care

NCT03013478
View directory record Official record
Conditions
Substance Abuse
Interventions
Standard Treatment As Usual (TAU), CBT4CBT program
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional Results available

Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders

NCT02742246
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Individual clinician-provided CBT, CBT4CBT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Bridgeport, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional

An Integrated Intervention Involving Recovery Coaching and Cognitive Behavioral Therapy for Opioid Use Disorder

NCT06102200
View directory record Official record
Conditions
Standard of Care, Standard of Care + CBT4CBT, Standard of Care + CBT4CBT + RC
Interventions
CBT4CBT, RC, Sandard of care
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional

Integration of Neurofunctional Phenotyping Into Investigation of CBT4CBT for AUD

NCT06190236
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Use Disorder
Interventions
Stand-alone web-based cognitive behavioral therapy (CBT4CBT) for alcohol use disorder
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 7, 2025 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional

CBT for Spanish Speakers

NCT02043210
View directory record Official record
Conditions
Substance Use
Interventions
Standard Treatment as Usual, CBT4CBT plus Standard treatment as usual
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
4
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Phase 1Phase 2 Interventional

Computer Based Training in Cognitive Behavioral Therapy Web-based

NCT01442597
View directory record Official record
Conditions
Substance Abuse
Interventions
Standard Treatment As Usual (TAU), Individual clinician-provided CBT, CBT4CBT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional Results available

CBT4CBT With Spanish Alcohol Users

NCT03474588
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Standard treatment (ST) PLUS web-based CBT4CBT, Standard Treatment (ST)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
5
States / cities
Bridgeport, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced Sep 3, 2026, 1:08 AM EDT
Active, not recruiting Not applicable Interventional

Black Church Treatment Study

NCT04580810
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
CBT4CBT in the Black Church
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 3, 2026, 1:08 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Social Functioning in Opioid Use Disorder

NCT07044466
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
CBT4CBT-Buprenorphine
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional

CBT4CBT for Women in Residential Treatment for Substance Use Disorders

NCT03678051
View directory record Official record
Conditions
Substance Use Disorders, Drug Abuse, Drug Addiction, Substance Abuse, Drug Use Disorders, Drug Dependence, Substance Addiction
Interventions
Treatment as Usual (TAU), TAU+CBT4CBT
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CBT4CBT-Buprenorphine + Recovery Coach for Office-based Buprenorphine

NCT04824404
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
CBT4CBT-Buprenorphine + Recovery Coach
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Sep 3, 2026, 1:08 AM EDT
Active, not recruiting Not applicable Interventional

Promoting Alcohol Treatment Engagement Post-hospitalization

NCT05338151
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Brief Negotiated Interview (BNI), BNI+facilitated provision of MAUD, Brief Negotiated Interview BNI+facilitated provision of MAUD+CBT4CBT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Phase 1Phase 2 Interventional

CBT4CBT for Office Based Buprenorphine

NCT03580902
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
CBT4CBT-Buprenorphine, Buprenorphine/naloxone
Behavioral · Drug
Lead sponsor
CBT4CBT, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional Results available

Feasibility of Providing Computerized CBT in the Black Church

NCT03579290
View directory record Official record
Conditions
Substance Abuse
Interventions
CBT4CBT program
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Sep 3, 2026, 1:08 AM EDT
Completed Not applicable Interventional

Web-based CBT4CBT for Alcohol

NCT01615497
View directory record Official record
Conditions
Alcohol Abuse or Dependence
Interventions
Standard Treatment as Usual (TAU), Web-based CBT4CBT for alcohol plus TAU, Web-based CBT with minimal clinical contact
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 8, 2020 · Synced Sep 3, 2026, 1:08 AM EDT
Recruiting Not applicable Interventional

Virtual Incentive Treatment for Alcohol

NCT06265506
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
Interventions
Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Sep 3, 2026, 1:08 AM EDT