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ClinicalTrials.gov public records Last synced Oct 25, 2026, 4:13 AM EDT

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Showing 433–456 of 1,579 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: CEASE Clear all
Active, not recruiting Phase 2 Interventional

A Phase II Trial of PD-L1 Therapy Combined With Anti-VEGF Therapy in Unresectable or Metastatic Melanoma

NCT04356729
View directory record Official record
Conditions
Clinical Stage III Cutaneous Melanoma AJCC v8, Stage IV Melanoma, Unresectable Stage III Cutaneous Melanoma, Unresectable Stage IV Cutaneous Melanoma
Interventions
Atezolizumab, Bevacizumab
Drug
Lead sponsor
F. Stephen Hodi, MD
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Not applicable Interventional

A Mindfulness Based Application for Smoking Cessation

NCT01982110
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Mindfulness based smoking cessation, Behavioral Smoking Cessation intervention
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 99 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke

NCT00307203
View directory record Official record
Conditions
Tobacco-Use Disorder, Schizophrenia, Psychotic Disorders
Interventions
bupropion SR, Cognitive Behavioral Group Therapy, nicotine replacement therapy
Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing the Efficacy of Smoking Quit Line in the Military (AFIII Renewal)

NCT02201810
View directory record Official record
Conditions
Initial Efficacy of Quit Line, Efficacy of Secondary Reengagement Intervention
Interventions
Rate reduction intervention, Recycling Group, Choice Group, Proactive QL
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
614 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Lackland Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Oct 25, 2026, 4:13 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examination of the Dynamic Relationships of Sleep, Physical Activity, and Circadian Rhythmicity With Neurobehavioral Heterogeneity in ADHD

NCT06810180
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder (ADHD), Sleep, Physical Activity
Interventions
Go/No-Go Task, Delay discounting task, Mirror Tracing Persistence Task, Spatial Span, Stop Signal Task, Flanker task
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
8 Years to 12 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Phase 1 Interventional

Vitamin D Testing and Treatment for COVID 19

NCT04407286
View directory record Official record
Conditions
Covid 19, Vitamin D Deficiency
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 30, 2021 · Synced Oct 25, 2026, 4:13 AM EDT
Active, not recruiting Phase 1 Interventional

A Feasibility Trial of Tazemetostat Plus CAR T Cell Therapy in B-cell Lymphomas

NCT05934838
View directory record Official record
Conditions
Follicular Lymphoma, B-Cell Lymphoma, Mantle Cell Lymphoma, Diffuse Large B Cell Lymphoma
Interventions
Tazemetostat Pill
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 25, 2026, 4:13 AM EDT
Recruiting Phase 2 Interventional

Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

NCT04363164
View directory record Official record
Conditions
Castration Resistant Metastatic Prostate Cancer
Interventions
Testosterone cypionate, Enzalutamide, Testosterone enanthate
Drug
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 90 Years · Male only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
6
States / cities
San Diego, California • Baltimore, Maryland • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Facilitating Smoking Cessation With Reduced Nicotine Cigarettes

NCT02796391
View directory record Official record
Conditions
Smoking Cessation
Interventions
Very Low Nicotine Content (VLNC) Cigarettes, One on One Counseling
Drug · Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Environments as Smoking Cues: Imaging Brain Substrates, Developing New Treatments (CameraCue)

NCT01840111
View directory record Official record
Conditions
Smoking, Healthy
Interventions
Quit Smoking 6 hours, Quit Smoking 24 hours
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 25, 2026, 4:13 AM EDT
Recruiting Phase 1Phase 2 Interventional

Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma

NCT07479979
View directory record Official record
Conditions
Relapse Multiple Myeloma, Refractory Multiple Myeloma
Interventions
Selinexor, Carfilzomib, Isatuximab, Isatuximab SC Wearable Injection System, Dexamethasone
Drug · Device
Lead sponsor
Natalie Callander
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Phase 2 Interventional Results available

A Study of a New Combination and Schedule of Chemotherapy Drugs for the Treatment of Head and Neck Cancer

NCT00148122
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Docetaxel, Capecitabine
Drug
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2014 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Does Capnography Prevent Hypoxemia During Endoscopic Retrograde Cholangiopancreatography and Endoscopic Ultrasound?

NCT00675415
View directory record Official record
Conditions
Hypoxemia
Interventions
Capnography
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
263 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 28, 2017 · Synced Oct 25, 2026, 4:13 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Knee Osteoarthritis Rehabilitation Through Rotational Inertia

NCT07424352
View directory record Official record
Conditions
Knee Arthritis, Osteoarthritis
Interventions
Eccentric resistance training
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pilot Text Messaging Intervention to Reduce Smoking in Office-based Buprenorphine and Inpatient Detoxification Patients

NCT02665208
View directory record Official record
Conditions
Smoking Cessation
Interventions
Treatment As Usual (TAU), Nicotine Replacement Therapies, Text Message Intervention (TMI)
Other · Drug · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Oct 25, 2026, 4:13 AM EDT
Active, not recruiting Not applicable Interventional

Unilateral vs Bilateral Application of Muscle Energy Techniques in Pelvic Somatic Dysfunction

NCT06266650
View directory record Official record
Conditions
Pelvic Somatic Dysfunction
Interventions
Osteopathic Treatment Technique- Muscle Energy Treatment
Other
Lead sponsor
The Touro College and University System
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Harlem, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Phase 1 Interventional

Smoking Cessation and Sexual Health in Men

NCT00833404
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine transdermal patch
Drug
Lead sponsor
University of Texas at Austin
Other
Eligibility
23 Years to 60 Years · Male only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 12, 2011 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Varenicline in Smokers With Cardiovascular Disease Who Wish to Quit Smoking

NCT00282984
View directory record Official record
Conditions
Smoking Cessation
Interventions
placebo, Varenicline
Drug
Lead sponsor
Pfizer
Industry
Eligibility
35 Years to 75 Years
Enrollment
714 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
3
States / cities
Hartford, Connecticut • Boston, Massachusetts • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Probiotic Administration on Mood

NCT05343533
View directory record Official record
Conditions
Depression, Sleep, Stress, Anxiety, Mood Disorders
Interventions
Probiotic
Dietary Supplement
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 50 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Short Messaging Service Program to Help Quit Smoking During Perioperative Period.

NCT03839043
View directory record Official record
Conditions
Tobacco Use Cessation, Perioperative/Postoperative Complications, Tobacco Smoking
Interventions
Brief behavioral intervention, SMS Program
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2021 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of a Tobacco Control Intervention in African-American Families

NCT01164306
View directory record Official record
Conditions
Tobacco Prevention, Environmental Tobacco Smoke Exposure, Tobacco Cessation
Interventions
LifeSkills Training, Healthy Lifestyle Behavior Choices, NRT and Motivational Interviewing (MI)
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
8 Years and older
Enrollment
688 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 2, 2015 · Synced Oct 25, 2026, 4:13 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Low Systemic/High Local Exercise Load in Peds SCD

NCT06387758
View directory record Official record
Conditions
Sickle Cell Anemia in Children
Interventions
Low systemic strength training, Moderate systemic exercise
Behavioral
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 25, 2026, 4:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Inappropriate Benzodiazepine Use Among Older Adults

NCT03405298
View directory record Official record
Conditions
Long Term Use of Benzodiazepine
Interventions
Educational Material, Supplemental Collaborative Care
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced Oct 25, 2026, 4:13 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Palbociclib After CDK and Endocrine Therapy (PACE)

NCT03147287
View directory record Official record
Conditions
Metastatic Breast Cancer
Interventions
Palbociclib, Fulvestrant, Avelumab
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
22
States / cities
Miami, Florida • Atlanta, Georgia • Chicago, Illinois + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 25, 2026, 4:13 AM EDT