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ClinicalTrials.gov public records Last synced Oct 30, 2026, 1:35 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 107 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: CHD Clear all
Withdrawn No phase listed Observational

Hematologic Ratios in Postoperative Acute Kidney Injury

NCT03658148
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Cardiac Surgery with Cardiopulmonary Bypass
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
0 Days to 31 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 6, 2024 · Synced Oct 30, 2026, 1:35 AM EDT
Withdrawn Phase 1 Interventional

Nitric Oxide During CPB to Reduce AKI in Neonates

NCT03946462
View directory record Official record
Conditions
Congenital Heart Disease, Acute Kidney Injury
Interventions
NO gas delivered during cardiac surgery, placebo gas delivered during cardiac surgery
Drug · Other
Lead sponsor
Fabio Savorgnan
Other
Eligibility
Up to 30 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 30, 2026, 1:35 AM EDT
Recruiting No phase listed Observational

Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD)

NCT06575270
View directory record Official record
Conditions
Hypoxemia, Skin Pigment, Congenital Heart Disease
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Up to 18 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 30, 2026, 1:35 AM EDT
Active, not recruiting No phase listed Observational

Congenital Heart Disease GEnetic NEtwork Study (CHD GENES)

NCT01196182
View directory record Official record
Conditions
Congenital Heart Defects
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 99 Years
Enrollment
32,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2032
U.S. locations
14
States / cities
Los Angeles, California • Palo Alto, California • San Francisco, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 30, 2026, 1:35 AM EDT
Not yet recruiting Not applicable Interventional

UltraTrac for Cardiac Output Monitoring in Congenital Heart Disease

NCT07866573
View directory record Official record
Conditions
Congenital Heart Disease, Cardiac Output, Hemodynamic Monitoring, Pediatric Heart Disease
Interventions
UltraTrac
Device
Lead sponsor
University of Minnesota
Other
Eligibility
0 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 30, 2026, 1:35 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Safety and Efficacy of APL180 in Healthy Volunteers and Patients With Coronary Heart Disease (CHD)

NCT00568594
View directory record Official record
Conditions
Coronary Heart Disease
Interventions
APL180, Placebo
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years to 75 Years
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 24, 2020 · Synced Oct 30, 2026, 1:35 AM EDT
Completed Phase 2 Interventional Results available

A Study of RO4607381 in Patients With Coronary Heart Disease (CHD) or a CHD Risk Equivalent.

NCT00353522
View directory record Official record
Conditions
Coronary Heart Disease
Interventions
Placebo, dalcetrapib
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 75 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
10
States / cities
Chicago, Illinois • Indianapolis, Indiana • Iowa City, Iowa + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 30, 2026, 1:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Using Digital Data to Predict CHD

NCT04574882
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Survey
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 74 Years
Enrollment
781 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 30, 2026, 1:35 AM EDT
Recruiting Phase 3 Interventional

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

NCT07136012
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Olpasiran, Placebo
Drug
Lead sponsor
Amgen
Industry
Eligibility
50 Years to 105 Years
Enrollment
11,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
205
States / cities
Alexander City, Alabama • Birmingham, Alabama • Daphne, Alabama + 170 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 30, 2026, 1:35 AM EDT
Active, not recruiting Not applicable Interventional

Improving Patient and Family Health Using Family-Centered Outcomes and Shared Decision-Making

NCT04437069
View directory record Official record
Conditions
Patient Decision Aids, Congenital Heart Disease, Congenital Heart Defect
Interventions
Decision Aid, Values Clarification Exercise
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 30, 2026, 1:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Analyzing How Genetics May Affect Response to High Blood Pressure Medications

NCT00563901
View directory record Official record
Conditions
Hypertension, Coronary Disease, Cerebrovascular Accident
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
37,939 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
2
States / cities
Minneapolis, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2014 · Synced Oct 30, 2026, 1:35 AM EDT
Recruiting Not applicable Interventional

Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment

NCT03891160
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
3D model of heart
Other
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
6
States / cities
Palo Alto, California • Gainesville, Florida • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 30, 2026, 1:35 AM EDT
Not listed Not applicable Interventional

The Sequencing for Detection in Congenital Heart Disease (SD-CHD) Study

NCT06244940
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Whole Genome Sequencing (WGC) from subject samples
Diagnostic Test
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Oct 30, 2026, 1:35 AM EDT
Recruiting No phase listed Observational

The Co-Op @ HeartWorks

NCT06469918
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Not listed
Lead sponsor
HeartWorks, Inc.
Other
Eligibility
0 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2050
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 30, 2026, 1:35 AM EDT
Recruiting Not applicable Interventional

Congenital Heart Disease Physical Activity Lifestyle Study V.2

NCT06003023
View directory record Official record
Conditions
Heart Defects, Congenital, Cardiovascular Disease Other
Interventions
Physical Activity Monitoring, Tailored Exercise Prescription, Healthy Lifestyle Education, Physical Activity Lifestyle Intervention Informed by the Theory of Planned Behavior
Behavioral
Lead sponsor
Jamie Jackson
Other
Eligibility
15 Years to 25 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 30, 2026, 1:35 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Evaluating Dysphagia in Neonates With CHD

NCT03045757
View directory record Official record
Conditions
Dysphagia of Newborn
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
1 Day to 3 Months
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Oak Lawn, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 30, 2026, 1:35 AM EDT
Completed No phase listed Observational Results available

Inflammatory Cytokine Quantification in Infants

NCT01155830
View directory record Official record
Conditions
Sepsis, Congenital Diaphragmatic Hernia, Neonatal Cardiopulmonary Failure
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 2 Months
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 4, 2015 · Synced Oct 30, 2026, 1:35 AM EDT
Completed Phase 3 Interventional

A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease

NCT01516541
View directory record Official record
Conditions
Cardiovascular Disease, Coronary Heart Disease, Dyslipidemia, Peripheral Arterial Disease (PAD)
Interventions
Background care, Placebo, dalcetrapib
Other · Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
45 Years and older
Enrollment
2,220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
121
States / cities
Birmingham, Alabama • Huntsville, Alabama • Anaheim, California + 112 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Oct 30, 2026, 1:35 AM EDT
Enrolling by invitation No phase listed Observational

Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

NCT06823115
View directory record Official record
Conditions
Acute Kidney Injury, Fluid Overload, Prematurity Complications, Risk Factors, Epidemiology, Chronic Kidney Disease(CKD), Hypertension
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
0 Minutes to 2 Weeks
Enrollment
8,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
53
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Palo Alto, California + 48 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2026 · Synced Oct 30, 2026, 1:35 AM EDT
Completed No phase listed Observational Results available

Pharmacokinetics of Acetaminophen in Pediatric Patients With Congenital Heart Disease

NCT04278625
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Acetaminophen
Drug
Lead sponsor
Peter Winch
Other
Eligibility
2 Years to 6 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 30, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Training Intensity on the CHD Risk Factors in Postmenopausal Women

NCT00000108
View directory record Official record
Conditions
Cardiovascular Diseases, Coronary Disease
Interventions
Exercise
Behavioral
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
50 Years to 65 Years · Female only
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 30, 2026, 1:35 AM EDT
Terminated Phase 2 Interventional Results available

Erythropoietin to Prevent Unnecessary Transfusions In Patients With Cyanotic CHD - A Prospective Control Trial

NCT02564796
View directory record Official record
Conditions
Cyanotic Congenital Heart Disease, Anemia, Cyanosis, Congenital Heart Disease
Interventions
Epoetin Alfa and Iron, Iron
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
Up to 8 Weeks
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Oct 30, 2026, 1:35 AM EDT
Completed No phase listed Observational

Genomic Basis of Neurodevelopmental and Brain Outcomes in Congenital Heart Disease (CHD Brain and Genes)

NCT03070197
View directory record Official record
Conditions
Heart Disease Congenital
Interventions
Exposure of interest: Brain MRI, Exposure of interest: neurodevelopmental assessments
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
8
States / cities
Los Angeles, California • San Francisco, California • New Haven, Connecticut + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Oct 30, 2026, 1:35 AM EDT
Completed Phase 3 Interventional Results available

12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe

NCT00525824
View directory record Official record
Conditions
Hypercholesterolemia, Coronary Heart Disease, Atherosclerosis
Interventions
Rosuvastatin (Crestor), Ezetimibe, Simvastatin
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years and older
Enrollment
1,743 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Brentwood, Tennessee
Source: ClinicalTrials.gov public record
Updated May 13, 2011 · Synced Oct 30, 2026, 1:35 AM EDT